Catalog No.
RHE87001
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
CLCK2, Chloride transporter ClC-5, ClC-5, CLCN5, H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N237/8
Genetic and pathological findings in a boy with psoriasis and C3 glomerulonephritis: A case report and literature review., PMID:32725812
Osteogenic role of endosomal chloride channels in MC3T3-E1 cells., PMID:20473779
Clcn5 knockout mice exhibit novel immunomodulatory effects and are more susceptible to dextran sulfate sodium-induced colitis., PMID:20181886
Disruption of clc-5 leads to a redistribution of annexin A2 and promotes calcium crystal agglomeration in collecting duct epithelial cells., PMID:16429322
ClC-5: role in endocytosis in the proximal tubule., PMID:15942052
A boy with Japanese Dent's disease exhibiting abnormal calcium metabolism and osseous disorder of the spine: defective megalin expression at the brushborder of renal proximal tubules., PMID:15524062
Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells., PMID:15489223
Biophysical and pharmacological characterization of hypotonically activated chloride currents in cortical astrocytes., PMID:15095372
Examination of megalin in renal tubular epithelium from patients with Dent disease., PMID:15052463
Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5., PMID:14675051
Coexpression of complementary fragments of ClC-5 and restoration of chloride channel function in a Dent's disease mutation., PMID:13679301
Expression of voltage-gated chloride channels in human glioma cells., PMID:12843258
The chloride channel ClC-4 contributes to endosomal acidification and trafficking., PMID:12746443
Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM., PMID:12475763
Human ClC-3 is not the swelling-activated chloride channel involved in cell volume regulation., PMID:11278960
Cellular and subcellular immunolocalization of ClC-5 channel in mouse kidney: colocalization with H+-ATPase., PMID:10600943
Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease., PMID:9931332
A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption., PMID:8969232
For research use only. Not for human or drug use.
