Catalog No.
PHF86201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RELB (Asp248-Asp492).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RELB,Transcription factor RelB,I-Rel
Purification
Purified by antigen affinity column.
Accession
Q01201
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion., PMID:39992708
CD40 induces PIR-A+ macrophages to promote chronic allograft rejection., PMID:39954660
B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection., PMID:39082968
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages., PMID:38594444
Effect of glutamine on the systemic innate immune response in broiler chickens challenged with Salmonella pullorum., PMID:38102601
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency., PMID:37938781
Vitamin D3 mitigates autoimmune inflammation caused by activation of myeloid dendritic cells in SLE., PMID:37702410
Functionalized Parylene Films for Enhancement of Antibody Production by Hybridoma Cells., PMID:37647153
BET inhibition targets ABC-DLBCL constitutive B-cell receptor signaling through PAX5., PMID:37184294
Tuning the expression of the bacterial relBE toxin-antitoxin system in Saccharomyces cerevisiae allows characterizing the subsequent growth inhibition., PMID:36722160
Sustained activation of non-canonical NF-κB signalling drives glycolytic reprogramming in doxorubicin-resistant DLBCL., PMID:36446947
Uncovering Novel Prognostic Factors of Sudden Sensorineural Hearing Loss by Whole-Genome Sequencing of Cell-Free DNA., PMID:36349665
Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa., PMID:35916405
Functional analysis of Escherichia coli K12 toxin-antitoxin systems as novel drug targets using a network biology approach., PMID:35853597
Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis., PMID:35543875
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity., PMID:35148840
Cyclic Helix B Peptide Prolongs Skin Allograft Survival via Inhibition of B Cell Immune Responses in a Murine Model., PMID:34054874
Noncanonical NF-κB Signaling Pathway in Liver Diseases., PMID:33604258
Quantitative assessment of NFκB transcription factor activity., PMID:33388338
Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against Candida albicans., PMID:32765468
Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice., PMID:30877171
Integrated RNA-seq and ChIP-seq analysis reveals a feed-forward loop regulating H3K9ac and key labor drivers in human placenta., PMID:30642670
Immature lung TNFR2- conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo., PMID:30327534
A systems medicine approach reveals disordered immune system and lipid metabolism in multiple sclerosis patients., PMID:29194580
RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation., PMID:28960101
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation., PMID:28837798
Parthenolide reduces gene transcription of prosurvival mediators in U937 cells., PMID:28361855
Bacterial Genome Editing via a Designed Toxin-Antitoxin Cassette., PMID:28094982
Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development., PMID:27457956
Functional characterization of RelBE toxin-antitoxin system in probiotic Bifidobacterium longum JDM301., PMID:27451444
Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases., PMID:27137501
Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling., PMID:26799990
The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition., PMID:26502963
Classical and alternative NF-κB signaling cooperate in regulating adipocyte differentiation and function., PMID:26403432
The effects of RelB deficiency on lymphocyte development and function., PMID:26385063
The AhR and NF-κB/Rel Proteins Mediate the Inhibitory Effect of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on the 3' Immunoglobulin Heavy Chain Regulatory Region., PMID:26377645
Potential Cross-Talk between Alternative and Classical NF-κB Pathways in Prostate Cancer Tissues as Measured by a Multi-Staining Immunofluorescence Co-Localization Assay., PMID:26186215
Methods to assess the activation of the alternative (noncanonical) NF-κB pathway by non-death TNF receptors., PMID:25736746
DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity., PMID:25362179
Imipramine exploits histone deacetylase 11 to increase the IL-12/IL-10 ratio in macrophages infected with antimony-resistant Leishmania donovani and clears organ parasites in experimental infection., PMID:25217162
Pathological activation of canonical nuclear-factor κB by synergy of tumor necrosis factor α and TNF-like weak inducer of apoptosis in mouse acute colitis., PMID:25022957
Transcription factors involved in prostate gland adaptation to androgen deprivation., PMID:24886974
Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2., PMID:24768114
Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB., PMID:24524692
Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR., PMID:24409185
NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens., PMID:24242887
Established thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development., PMID:24086471
RelB, together with RelA, sustains cell survival and confers proteasome inhibitor sensitivity of chronic lymphocytic leukemia cells from bone marrow., PMID:24042463
[Distribution of genes of toxin-antitoxin systems of mazEF and relBE families in bifidobacteria from human intestinal microbiota]., PMID:23755531
The chemotherapeutic agent topotecan differentially modulates the phenotype and function of dendritic cells., PMID:23666509
For research use only. Not for human or drug use.
