Catalog No.
RHE25201
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Adenylyl cyclase 8, Adenylate cyclase type VIII, AC8, ADCY8, Adenylate cyclase type 8, Ca(2+)/calmodulin-activated adenylyl cyclase, ATP pyrophosphate-lyase 8
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N208/15
Complex patterns on HEp-2 indirect immunofluorescence assay in a large sample referred for anti-cell autoantibodies detection., PMID:38283335
Phage display technology for fabricating a recombinant monoclonal ScFv antibody against tetanus toxin., PMID:37663798
Clinical Significance of Antinucleolar Antibodies: Biomarkers for Autoimmune Diseases, Malignancies, and others., PMID:35258843
A new diagnostic algorithm for pattern-oriented autoantibody testing according to the ICAP nomenclature: A pilot study., PMID:32540447
The AC8 IgG3 monoclonal anti-cholesterol antibody modulates uptake and presentation of antigens for T cell activation., PMID:22305930
Ocular distribution, spectrum of activity, and in vivo viral neutralization of a fully humanized anti-herpes simplex virus IgG Fab fragment following topical application., PMID:22203590
Some new faces of membrane microdomains: a complex confocal fluorescence, differential polarization, and FCS imaging study on live immune cells., PMID:18163467
Ca2+-stimulated adenylyl cyclase isoform AC1 is preferentially expressed in guinea-pig sino-atrial node cells and modulates the I(f) pacemaker current., PMID:17540702
Distinct regional and subcellular localization of adenylyl cyclases type 1 and 8 in mouse brain., PMID:17335981
Ethanol induces apoptotic death of developing beta-endorphin neurons via suppression of cyclic adenosine monophosphate production and activation of transforming growth factor-beta1-linked apoptotic signaling., PMID:16326933
Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa., PMID:12950106
Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome., PMID:12213643
Overexpression of Gs proteins and adenylyl cyclase in normal and diabetic islets., PMID:12142742
Localization of adenylyl cyclase proteins in the rodent retina., PMID:12007833
Adenylyl cyclase isoform expression in non-diabetic and diabetic Goto-Kakizaki (GK) rat pancreas. Evidence for distinct overexpression of type-8 adenylyl cyclase in diabetic GK rat islets., PMID:10766260
Positive cooperative effects between receptors induced by an anti-human growth hormone allosteric monoclonal antibody., PMID:10724449
Monoclonal antibodies to human growth hormone modulate its biological properties., PMID:7753048
Allosteric effects of monoclonal antibodies on human growth hormone., PMID:7531816
Low-molecular weight B cell growth factor (BCGF-12KD) as an autocrine growth factor in B cell chronic lymphocytic leukemia., PMID:1623931
Radiolabeled anti-CD45 monoclonal antibodies target lymphohematopoietic tissue in the macaque., PMID:1832994
Monoclonal antibodies as probes to study the human growth hormone-binding domain to lactogenic rat liver receptors., PMID:1696878
Relationship between the antigenic topography and the structure of human growth hormone., PMID:1696877
Monoclonal antibodies to human growth hormone induce an allosteric conformational change in the antigen., PMID:2473953
Production and preliminary characterization of murine monoclonal antibodies to Ichthyophthirius multifiliis, a protozoan parasite of fish., PMID:2431637
Two human IgM myeloma proteins with unusual specificities for streptococcal carbohydrate-associated epitopes., PMID:2579417