Catalog No.
PHF70601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CXCL6/GCP-2 (Val40-Asn114).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
C-X-C motif chemokine 6,SCYB6,Small-inducible cytokine B6,CXCL6,CKA-3,Chemokine alpha 3,Granulocyte chemotactic protein 2,GCP2,GCP-2
Purification
Purified by antigen affinity column.
Accession
P80162
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting Deltex E3 Ubiquitin Ligase 2 Inhibits Tumor-associated Neutrophils and Sensitizes Hepatocellular Carcinoma Cells to Immunotherapy., PMID:39733452
Circulating cytokine associations with clinical outcomes in melanoma patients treated with combination nivolumab plus ipilimumab., PMID:39699928
Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI., PMID:39374793
Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization of Flare Treatment in EFFISAYIL 1., PMID:39004117
Cx1Mab-1: A Novel Anti-mouse CXCR1 Monoclonal Antibody for Flow Cytometry., PMID:38593439
Acid-sensing receptor GPR4 plays a crucial role in lymphatic cancer metastasis., PMID:38410865
Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology., PMID:38405760
Spatial characterization of interface dermatitis in cutaneous lupus reveals novel chemokine ligand-receptor pairs that drive disease., PMID:38260617
Local analgesia of electroacupuncture is mediated by the recruitment of neutrophils and released β-endorphins., PMID:37027145
Mirikizumab Regulates Genes Involved in Ulcerative Colitis Disease Activity and Anti-TNF Resistance: Results From a Phase 2 Study., PMID:36881820
Integrative characterisation of secreted factors involved in intercellular communication between prostate epithelial or cancer cells and fibroblasts., PMID:36608258
Effects of aspirin, vitamin D3, and progesterone on pregnancy outcomes in an autoimmune recurrent spontaneous abortion model., PMID:34133541
Transforming growth factor-β1 inhibits interleukin-1β-induced expression of inflammatory genes and Cathepsin S activity in human vascular smooth muscle cells., PMID:33683760
Pristane/Hypoxia (PriHx) Mouse as a Novel Model of Pulmonary Hypertension Reflecting Inflammation and Fibrosis., PMID:32522898
Assessment of pulmonary tissue responses in pigs challenged with PRRSV Lena strain shows better protection after immunization with field than vaccine strains., PMID:30827397
Cytokines and chemokines expression in serum of patients with neuromyelitis optica., PMID:30718956
CXCL6 is an important paracrine factor in the pro-angiogenic human cardiac progenitor-like cell secretome., PMID:28970523
Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis., PMID:28012239
CXCL16 regulates renal injury and fibrosis in experimental renal artery stenosis., PMID:27496882
Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16., PMID:25683115
The chemokine ligand CXCL16 is an indicator of bacterial infection in necrotizing pancreatitis., PMID:25661686
Pharmacological inhibition of the chemokine CXCL16 diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury., PMID:25372401
HIF-1α plays a role in the chemotactic migration of hepatocarcinoma cells through the modulation of CXCL6 expression., PMID:25323032
A homeostatic function of CXCR2 signalling in articular cartilage., PMID:25135253
oxLDL-induced lipid accumulation in glomerular podocytes: role of IFN-γ, CXCL16, and ADAM10., PMID:24752304
The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases., PMID:24678812
Tumor-conditioned Gr-1(+)CD11b(+) myeloid cells induce angiogenesis through the synergistic action of CCL2 and CXCL16 in vitro., PMID:24388986
Molecular profiling of acute and chronic rejections of renal allografts., PMID:24302958
Regulation of the development of the hepatic B cell compartment during Schistosoma mansoni infection., PMID:24038090
CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model., PMID:23975892
Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells., PMID:23150618
Nonstructural Nipah virus C protein regulates both the early host proinflammatory response and viral virulence., PMID:22837207
Psoriasis: rationale for targeting interleukin-17., PMID:22716185
CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNS., PMID:22378888
TWEAK (tumor necrosis factor-like weak inducer of apoptosis) activates CXCL16 expression during renal tubulointerstitial inflammation., PMID:22278019
Sjögren's syndrome autoantibodies provoke changes in gene expression profiles of inflammatory cytokines triggering a pathway involving TACE/NF-κB., PMID:22157716
SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation., PMID:21471570
Mycobacterium tuberculosis lipoarabinomannan enhances LPS-induced TNF-α production and inhibits NO secretion by engaging scavenger receptors., PMID:21419839
Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity., PMID:21279329
Isotypic neutralizing antibodies against mouse GCP-2/CXCL6 inhibit melanoma growth and metastasis., PMID:21236563
CXCL16 contributes to neutrophil recruitment to cerebrospinal fluid in pneumococcal meningitis., PMID:20874518
Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation., PMID:20848509
Elevated expression of CXC chemokines in pediatric osteosarcoma patients., PMID:20806347
Expression and function of CXCL16 in a novel model of gout., PMID:20506383
Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts., PMID:20219013
Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer., PMID:19826039
"Reverse degradomics", monitoring of proteolytic trimming by multi-CE and confocal detection of fluorescent substrates and reaction products., PMID:19621364
Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production., PMID:19575365
CXCL16 and oxLDL are induced in the onset of diabetic nephropathy., PMID:19426159
Gonadotropin-releasing hormone-regulated chemokine expression in human placentation., PMID:19369450
For research use only. Not for human or drug use.
