Anti-PSD-95 Antibody (K28/74)

Catalog No.

RHB78602

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

DLGAP3, SAPAP3, SAP90/PSD-95-associated protein 3, PSD-95/SAP90-binding protein 3, DAP3, Disks large-associated protein 3, DAP-3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

K28/74

High-affinity detection of biotinylated endogenous neuroligin-1 at excitatory and inhibitory synapses using a tagged knock-in mouse., PMID:40424132

Combining nanobody labeling with STED microscopy reveals input-specific and layer-specific organization of neocortical synapses., PMID:40184426

Input-Specific Localization of NMDA Receptor GluN2 Subunits in Thalamocortical Neurons., PMID:40123534

eSylites: Synthetic Probes for Visualization and Topographic Mapping of Single Excitatory Synapses., PMID:40111234

Anti-NMDAR1 antibody impairs dendritic branching in immature cultured neurons., PMID:39434510

Targeting TrkB-PSD-95 coupling to mitigate neurological disorders., PMID:38886937

A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm., PMID:38110034

Autoimmune receptor encephalitis in ApoE‑/‑ mice induced by active immunization with NMDA1., PMID:37921064

Activation of the CD200/CD200R1 axis attenuates neuroinflammation and improves postoperative cognitive dysfunction via the PI3K/Akt/NF-κB signaling pathway in aged mice., PMID:37902837

Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept., PMID:37842184

Visualizing the triheteromeric N-methyl-D-aspartate receptor subunit composition., PMID:37292368

Flow Cytometry of Synaptoneurosomes (FCS) Reveals Increased Ribosomal S6 and Calcineurin Proteins in Activated Medial Prefrontal Cortex to Nucleus Accumbens Synapses., PMID:37160369

Simple and Highly Efficient Detection of PSD95 Using a Nanobody and Its Recombinant Heavy-Chain Antibody Derivatives., PMID:37108454

Effect of 3D Synthetic Microscaffold Nichoid on the Morphology of Cultured Hippocampal Neurons and Astrocytes., PMID:35805092

Microglial synaptic pruning on axon initial segment spines of dentate granule cells: Sexually dimorphic effects of early-life stress and consequences for adult fear response., PMID:33890333

Levetiracetam and N-Cadherin Antibody Alleviate Brain Pathology Without Reducing Early Epilepsy Development After Focal Non-convulsive Status Epilepticus in Rats., PMID:33716930

CaMKII Phosphorylation Regulates Synaptic Enrichment of Shank3., PMID:33568460

Anti-Lingo-1 antibody ameliorates spatial memory and synapse loss induced by chronic stress., PMID:32965038

CD44 Can Compensate for IgSF11 Deficiency by Associating with the Scaffold Protein PSD-95 during Osteoclast Differentiation., PMID:32290171

Inhibition of steroid receptor coactivator-1 in the hippocampus impairs the consolidation and reconsolidation of contextual fear memory in mice., PMID:32006528

Expression of GluA2-containing calcium-impermeable AMPA receptors on dopaminergic amacrine cells in the mouse retina., PMID:31819340

Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels., PMID:31651360

Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain., PMID:31625608

Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules., PMID:31586061

Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes., PMID:31558769

Bisphenol-A exposure induced neurotoxicity in glutamatergic neurons derived from human embryonic stem cells., PMID:30953815

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis., PMID:30881339

Caffeine inhibits hypoxia-induced nuclear accumulation in HIF-1α and promotes neonatal neuronal survival., PMID:30822423

Mouse model of anti-NMDA receptor post-herpes simplex encephalitis., PMID:30697582

High-resolution Immunoelectron Microscopy Techniques for Revealing Distinct Subcellular Type 1 Cannabinoid Receptor Domains in Brain., PMID:33654890

Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography., PMID:30581381

The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons., PMID:30385274

The Protective Effects and the Involved Mechanisms of Tanshinone IIA on Sepsis-Induced Brain Damage in Mice., PMID:30255286

3D imaging of PSD-95 in the mouse brain using the advanced CUBIC method., PMID:30208945

Phosphorylation of synaptic GTPase-activating protein (synGAP) by polo-like kinase (Plk2) alters the ratio of its GAP activity toward HRas, Rap1 and Rap2 GTPases., PMID:30049443

Chronic Toxoplasma gondii Infection Induces Anti-N-Methyl-d-Aspartate Receptor Autoantibodies and Associated Behavioral Changes and Neuropathology., PMID:30037790

Blocking of BDNF-TrkB signaling inhibits the promotion effect of neurological function recovery after treadmill training in rats with spinal cord injury., PMID:30002472

Increased Neuroligin 2 Levels in the Postsynaptic Membrane in Spinal Dorsal Horn may Contribute to Postoperative Pain., PMID:29715511

[Efficient discovery and capturing of nNOS-PSD-95 uncouplers from Trifolium pratense]., PMID:29600650

Novel surface imprinted magnetic mesoporous silica as artificial antibodies for efficient discovery and capture of candidate nNOS-PSD-95 uncouplers for stroke treatment., PMID:32254217

Assembly of Taurine Transporter (Slc6a6) with Na+-H+ Exchanger Regulatory Factor 1 (Slc9a3r1) Improves GABA Transport Activity by Increasing the Maximum Transport Velocity., PMID:29491210

Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice., PMID:28412140

Down-Regulated Drebrin Aggravates Cognitive Impairments in a Mouse Model of Alzheimer's Disease., PMID:28398234

Somatic and neuritic spines on tyrosine hydroxylase-immunopositive cells of rat retina., PMID:28035673

MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density., PMID:27756895

Mapping the connectivity of serotonin transporter immunoreactive axons to excitatory and inhibitory neurochemical synapses in the mouse limbic brain., PMID:27485750

Neuropilin-1 (NRP-1)/GIPC1 pathway mediates glioma progression., PMID:27481513

GluA2-Containing AMPA Receptors Distinguish Ribbon-Associated from Ribbonless Afferent Contacts on Rat Cochlear Hair Cells., PMID:27257620

A novel recombinant 6Aβ15-THc-C chimeric vaccine (rCV02) mitigates Alzheimer's disease-like pathology, cognitive decline and synaptic loss in aged 3 × Tg-AD mice., PMID:27255752

A Novel Aβ B-Cell Epitope Vaccine (rCV01) for Alzheimer's Disease Improved Synaptic and Cognitive Functions in 3 × Tg-AD Mice., PMID:27147259

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