Catalog No.
PHF69601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CCL20/MIP-3-alpha (Ser28-Met96).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Beta-chemokine exodus-1,SCYA20,LARC,C-C motif chemokine 20,Liver and activation-regulated chemokine,Small-inducible cytokine A20,MIP-3-alpha,CCL20,MIP3A,Macrophage inflammatory protein 3 alpha,CC chemokine LARC
Purification
Purified by antigen affinity column.
Accession
P78556
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Therapeutic Intervention of an Intranasally Administered Monoclonal Antibody Targeting the SARS-CoV-2 Omicron Spike Protein Against SARS-CoV-2 Omicron Infection in Mice., PMID:40465408
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma., PMID:40374617
Validation of an Automated Cell Counter Method for HLA-DR and CD3 Expression in Cells Obtained from Low Volume Human Tears., PMID:40361942
CCL20-CCR6 signaling in tumor microenvironment: Functional roles, mechanisms, and immunotherapy targeting., PMID:40348067
Correlation among ocular surface changes and systemic hematologic indexes and disease activity in primary Sjögren's syndrome: a cross-sectional study., PMID:40329232
Novel Vaccines Targeting the Highly Conserved SARS-CoV-2 ORF3a Ectodomain Elicit Immunogenicity in Mouse Models., PMID:40266087
Persistence of dysfunctional immune response 12 months after SARS-CoV-2 infection and their relationship with pulmonary sequelae and long COVID., PMID:40247373
Enhanced mucosal immune response through nanoparticle delivery system based on chitosan-catechol and a recombinant antigen targeted towards M cells., PMID:40010449
MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination., PMID:39877094
Infant respiratory infections modulate lymphocyte homing to breast milk., PMID:39867906
Galectin-1-Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs., PMID:39853961
Group B Streptococcal Membrane Vesicles Induce Proinflammatory Cytokine Production and Are Sensed in an NLRP3 Inflammasome-Dependent Mechanism in a Human Macrophage-like Cell Line., PMID:39761308
Innate immune response after BNT162b2 COVID-19 vaccination associates with reactogenicity., PMID:39734394
Progress of CCL20-CCR6 in the airways: a promising new therapeutic target., PMID:39731176
CCL20 chemokine and other proinflammatory markers after Ad26.COV2.S vaccination., PMID:39435167
Elevated serum IL-17 A and CCL20 levels as potential biomarkers in major psychotic disorders: a case-control study., PMID:39394574
Chiral Intranasal Nanovaccines as Antivirals for Respiratory Syncytial Virus., PMID:39221522
Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients with locally advanced and metastatic cutaneous squamous cell carcinoma., PMID:39206096
Serum Concentrations of Chemokines CCL20, CXCL8 and CXCL10 in Relapsing-Remitting Multiple Sclerosis and Their Association with Presence of Antibodies against Epstein-Barr Virus., PMID:39125633
DDR2/STAT3 Positive Feedback Loop Mediates the Immunosuppressive Microenvironment by Upregulating PD-L1 and Recruiting MDSCs in Oxaliplatin-Resistant HCC., PMID:38969205
Targeting IL-1 controls refractory pityriasis rubra pilaris., PMID:38959302
Novel Therapies for ANCA-associated Vasculitis: Apilimod Ameliorated Endothelial Cells Injury through TLR4/NF-κB Pathway and NLRP3 Inflammasome., PMID:38910483
Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization., PMID:38852736
Immunological Signatures in Blood and Urine in 80 Individuals Hospitalized during the Initial Phase of COVID-19 Pandemic with Quantified Nicotine Exposure., PMID:38612525
AMPK activation modulates IL-36-induced inflammatory responses by regulating IκBζ expression in the skin., PMID:38532634
Status of B-Lymphocyte Subsets and Their Homing Markers in Patients With Post-Kala-Azar Dermal Leishmaniasis., PMID:38527908
Serum levels of CXCL5 are decreased and correlate with circulating platelet counts in systemic lupus erythematosus., PMID:38439196
Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921
The functional role of CST1 and CCL26 in asthma development., PMID:38270326
Expression of Inflammatory Genes in Murine Lungs in a Model of Experimental Pulmonary Hypertension: Effects of an Antibody-Based Targeted Delivery of Interleukin-9., PMID:38247549
Role of the CCL20/CCR6 axis in tubular epithelial cell injury: Kidney-specific translational insights from acute kidney injury to chronic kidney disease., PMID:38197598
Increased gene expression of CCR6 and RORγt in peripheral blood cells of rheumatoid arthritis patients and their correlation with anti-cyclic citrullinated peptide and disease activity., PMID:38156398
Microbiota promotes recruitment and pro-inflammatory response of caecal macrophages during E. tenella infection., PMID:38098020
High-dimensional single-cell proteomics analysis of esophageal squamous cell carcinoma reveals dynamic alterations of the tumor immune microenvironment after neoadjuvant therapy., PMID:38016720
What Is New in Cutaneous T Cell Lymphoma?, PMID:37874473
Role of CD23 Activated ERK Signaling Pathway in the Pathogenesis of Eosinophilic Chronic Sinusitis with Nasal Polyps., PMID:37678868
GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity., PMID:37554323
Application of spatial transcriptomics analysis using the Visium system for the mouse nasal cavity after intranasal vaccination., PMID:37545501
Infiltrated IL-17A-producing gamma delta T cells play a protective role in sepsis-induced liver injury and are regulated by CCR6 and gut commensal microbes., PMID:37475963
Establishment of a Novel Anti-Human CCR6 Monoclonal Antibody C6Mab-19 with the High Binding Affinity in Flow Cytometry., PMID:37428612
Elevated nuclear PIGL disrupts the cMyc/BRD4 axis and improves PD-1 blockade therapy by dampening tumor immune evasion., PMID:37280393
Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C6Mab-13) Using 1× Alanine Scanning., PMID:37218898
The necroptosis related gene LGALS3 can be used as a biomarker for the adverse progression from chronic HBV infection to HCC., PMID:37180150
Atlas of the anatomical localization of atypical chemokine receptors in healthy mice., PMID:37159457
CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases., PMID:37092451
Cell-matrix interactions control biliary organoid polarity, architecture, and differentiation., PMID:36972396
The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis., PMID:36924892
A modified ELISA assay differentiates CCL20 locked dimers from wild-type monomers., PMID:36863695
Targeting LAYN inhibits colorectal cancer metastasis and tumor-associated macrophage infiltration induced by hyaluronan oligosaccharides., PMID:36805871
Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis., PMID:36788737
For research use only. Not for human or drug use.
