Anti-TrpA1 Antibody (N433/73)

Catalog No.

RHB30201

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Transformation-sensitive protein p120, TRPA1, Transient receptor potential cation channel subfamily A member 1, Ankyrin-like with transmembrane domains protein 1, ANKTM1, Wasabi receptor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N433/73

TRPV1 Defends the Healthy Murine Cornea against Staphylococcus aureus Adhesion Independently of Sensory Nerve Firing., PMID:40291673

Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine., PMID:40036725

Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1., PMID:39746519

The Expression of Cannabinoid and Cannabinoid-Related Receptors on the Gustatory Cells of the Piglet Tongue., PMID:39407543

Hyperalgesic Effect Evoked by il-16 and its Participation in Inflammatory Hypernociception in Mice., PMID:39152360

High humidity and NO2 co-exposure exacerbates allergic asthma by increasing oxidative stress, inflammatory and TRP protein expressions in lung tissue., PMID:38759746

Correlation of TRPA1 RNAscope and Agonist Responses., PMID:38725415

Transient Receptor Potential Ankyrin 1-dependent Activation of Extracellular Signal-regulated Kinase 2 in the Cerebral Cortices Contributes to Cortical Spreading Depolarization., PMID:38417540

Transient receptor potential ankyrin 1 (TRPA1) and transient receptor potential melastatin 8 (TRPM8) in human odontoblast-like cells participate in lipopolysaccharide-induced immune response., PMID:37683373

Zhenxin Anshen formula ameliorates atopic der-matitis-like skin dysfunction in mice and regulation of transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 in Neural pathways., PMID:37679976

PIEZO1 promotes ATP release from periodontal ligament cells following compression force., PMID:37632763

Enhanced production of IL-2 from anti-CD3 antibody-stimulated mouse spleen cells by caffeic acid phenethyl ester, a major component of Chinese propolis., PMID:37595745

Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure., PMID:36371551

Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems., PMID:36232883

Cannabinoid receptors in the inflammatory cells of canine atopic dermatitis., PMID:36187821

Cannabidiol: Influence on B Cells, Peripheral Blood Mononuclear Cells, and Peripheral Blood Mononuclear Cell/Rheumatoid Arthritis Synovial Fibroblast Cocultures., PMID:35920857

Distribution of Cannabinoid Receptors in Keratinocytes of Healthy Dogs and Dogs With Atopic Dermatitis., PMID:35873682

Study on the antipruritic mechanism of Zanthoxylum bungeanum and Zanthoxylum schinifolium volatile oil on chronic eczema based on H1R and PAR-2 mediated GRPR pathway., PMID:35789407

Enhanced production of IL-2 from anti-CD3 antibody-stimulated mouse spleen cells by artepillin C, a major component of Brazilian green propolis., PMID:35667586

Peptidergic neurons of the Edinger-Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in humans who died by suicide., PMID:35508327

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine., PMID:35325034

Functional Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Ion Channels Are Overexpressed in Human Oral Squamous Cell Carcinoma., PMID:35163843

The PACAP pathway is independent of CGRP in mouse models of migraine: possible new drug target?, PMID:35136961

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice., PMID:35115501

Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain., PMID:35077502

TRPA1-Mediated Src Family Kinases Activity Facilitates Cortical Spreading Depression Susceptibility and Trigeminovascular System Sensitization., PMID:34830154

Identification of Trigeminal Sensory Neuronal Types Innervating Masseter Muscle., PMID:34580157

H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc., PMID:34506603

CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine., PMID:34407650

Pain Control by Targeting Oxidized Phospholipids: Functions, Mechanisms, Perspectives., PMID:33569042

Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum., PMID:33494452

A basophil-neuronal axis promotes itch., PMID:33450207

Expression of cannabinoid and cannabinoid-related receptors in the oral mucosa of healthy cats and cats with chronic gingivostomatitis., PMID:33174485

Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine., PMID:33131305

Effects of activation of skin ion channels TRPM8, TRPV1, and TRPA1 on the immune response. Comparison with effects of cold and heat exposure., PMID:33077140

TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3., PMID:32863706

Exposure to formaldehyde at low temperatures aggravates allergic asthma involved in transient receptor potential ion channel., PMID:32798733

TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3., PMID:38860239

Developmental studies on the acquisition of perception conducting pathways via TRP channels in rat molar odontoblasts using immunohistochemistry and RT-qPCR., PMID:31848975

Validation of antibodies for the specific detection of human TRPA1., PMID:31811235

Aging of mouse intervertebral disc and association with back pain., PMID:30936040

ROS/TRPA1/CGRP signaling mediates cortical spreading depression., PMID:30841847

Repeated exposure to temperature variation exacerbates airway inflammation through TRPA1 in a mouse model of asthma., PMID:30440113

Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma., PMID:29975347

Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines., PMID:29864146

TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia., PMID:29754249

The Transient Receptor Potential Ankyrin Type 1 Plays a Critical Role in Cortical Spreading Depression., PMID:29719223

Antinociception by the anti-oxidized phospholipid antibody E06., PMID:29679953

The effect of neutralization of nerve growth factor (NGF) on bladder and urethral dysfunction in mice with spinal cord injury., PMID:29516546

Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats., PMID:28824373

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