Catalog No.
RHA49302
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
INPP4B, Inositol polyphosphate 4-phosphatase type II, Type II inositol 3,4-bisphosphate 4-phosphatase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N171/17
Plausible role of INPP4A dysregulation in idiopathic pulmonary fibrosis., PMID:38720166
Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b., PMID:37389566
Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment., PMID:32778095
IRF2-INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells., PMID:30876449
Secretory Inositol Polyphosphate 4-Phosphatase Protects against Airway Inflammation and Remodeling., PMID:30335467
Inhibitory receptor FcγRIIb mediates the effects of IgG on a phagosome acidification and a sequential dephosphorylation system comprising SHIPs and Inpp4a., PMID:28409542
Prognostic value of INPP4B protein immunohistochemistry in ovarian cancer., PMID:26189250
INPP4B overexpression is associated with poor clinical outcome and therapy resistance in acute myeloid leukemia., PMID:25736236
An integrative analysis of PIK3CA mutation, PTEN, and INPP4B expression in terms of trastuzumab efficacy in HER2-positive breast cancer., PMID:25542038
INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival., PMID:25284366
Transcriptional CCND1 expression as a predictor of poor response to neoadjuvant chemotherapy with trastuzumab in HER2-positive/ER-positive breast cancer., PMID:25200445
The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol., PMID:10097090
For research use only. Not for human or drug use.
