Catalog No.
PHF56501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAC1 (Met1-Leu192).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ras-related C3 botulinum toxin substrate 1,Ras-like protein TC25,TC25,p21-Rac1,Cell migration-inducing gene 5 protein,RAC1
Purification
Purified by antigen affinity column.
Accession
P63000
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1., PMID:40225568
E-Cadherin Is Important in the In Vitro Postnatal Development and Function of Pig Islets., PMID:40149603
Inclusion of ΑVβ3 integrin into extracellular vesicles in a caveolin-1 tyrosine-14- phosphorylation dependent manner and subsequent transfer to recipient melanoma cells promotes migration, invasion and metastasis., PMID:40098186
Trastuzumab Decreases the Expression of G1/S Regulators and Syndecan-4 Proteoglycan in Human Rhabdomyosarcoma., PMID:40076757
Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration., PMID:40053038
RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs., PMID:39992626
Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer., PMID:39900574
In Situ Proefferocytosis Microspheres as Macrophage Polarity Converters Accelerate Osteoarthritis Treatment., PMID:39780612
aPKC/Par3/Par6 polarity complexes regulate podocyte motility and crescent formation in the progression of ANCA-associated vasculitis., PMID:39700430
Beta cell-specific PAK1 enrichment ameliorates diet-induced glucose intolerance in mice by promoting insulin biogenesis and minimising beta cell apoptosis., PMID:39404845
DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress., PMID:39224830
Significance of RCC2, Rac1 and p53 Expression in Breast Infiltrating Ductal Carcinoma; An Immunohistochemical Study., PMID:39118792
The Roles of RAC1 and RAC1B in Colorectal Cancer and Their Potential Contribution to Cetuximab Resistance., PMID:39001533
Radiation-induced eCIRP impairs macrophage bacterial phagocytosis., PMID:38920274
Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor., PMID:38849345
Novel mechanisms of Anshen Dingzhi prescription against PTSD: Inhibiting DCC to modulate synaptic function and inflammatory responses., PMID:38848974
KIF1C and new Huntingtin-interacting protein 1 binding proteins regulate rheumatoid arthritis fibroblast-like synoviocytes' phenotypes., PMID:38726004
The Crosstalk between N-Formyl Peptide Receptors and uPAR in Systemic Sclerosis: Molecular Mechanisms, Pathogenetic Role and Therapeutic Opportunities., PMID:38542130
Clinical and functional spectrum of RAC2-related immunodeficiency., PMID:38194689
Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6., PMID:38159849
SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages., PMID:38135024
A personalized network framework reveals predictive axis of anti-TNF response across diseases., PMID:38118442
LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress., PMID:37540188
Effects of Simvastatin on RBL-2H3 Cell Degranulation., PMID:37394638
miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto's thyroiditis., PMID:37280674
3,5,3'-Triiodo-L-Thyronine Regulates Actin Cytoskeleton Dynamic in The Differentiated PC-12 Cells during Hypoxia through An αvβ3 Integrin., PMID:37210645
Peritoneal autoantibody profiling identifies p53 as an autoantibody target in endometriosis., PMID:36828054
B cell receptor-induced IL-10 production from neonatal mouse CD19+CD43- cells depends on STAT5-mediated IL-6 secretion., PMID:36735294
RAC1, a Potential Diagnostic and Prognostic Marker for Diffuse Large B Cell Lymphoma., PMID:36552804
Recent topics and advanced therapies in chronic granulomatous disease., PMID:36534309
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage., PMID:36229446
Single-cell RNA sequencing of CSF reveals neuroprotective RAC1+ NK cells in Parkinson's disease., PMID:36211372
A report on the potential of Rac1/pSTAT3 protein levels in T lymphocytes to assess the pharmacodynamic effect of thiopurine therapy in Inflammatory Bowel Disease patients., PMID:36138194
Annexin A2 and Kidney Diseases., PMID:36120574
Tripartite split-GFP assay to identify selective intracellular nanobody that suppresses GTPase RHOA subfamily downstream signaling., PMID:36059552
Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone., PMID:35927428
Adaptation and Changes in Actin Dynamics and Cell Motility as Early Responses of Cultured Mammalian Cells to Altered Gravitational Vector., PMID:35682810
CARD9 Mediates Pancreatic Islet Beta-Cell Dysfunction Under the Duress of Hyperglycemic Stress., PMID:35362297
Pro-Inflammatory Cytokines Trigger the Overexpression of Tumour-Related Splice Variant RAC1B in Polarized Colorectal Cells., PMID:35326545
Clinical utility of PDX cohorts to reveal biomarkers of intrinsic resistance and clonal architecture changes underlying acquired resistance to cetuximab in HNSCC., PMID:35260570
Impaired p47phox phosphorylation in neutrophils from patients with p67phox-deficient chronic granulomatous disease., PMID:35108370
Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target., PMID:34611509
HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson's disease models., PMID:34593974
Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics., PMID:34582006
Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor., PMID:34575873
The brain-derived neurotrophic factor prompts platelet aggregation and secretion., PMID:34546355
The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualizing stimulus define the cells' potential for decidualization success., PMID:34524461
RAGE and αVβ3-integrin are essential for suPAR signaling in podocytes., PMID:34166766
MFG-E8 Regulates Vascular Smooth Muscle Cell Migration Through Dose-Dependent Mediation of Actin Polymerization., PMID:34041925
The anti-Rac1-GTP antibody and the detection of active Rac1: a tool with a fundamental flaw., PMID:33910489
For research use only. Not for human or drug use.
