Catalog No.
YVV29801
Expression system
E. coli
Species
Human metapneumovirus (strain CAN97-83) (HMPV)
Protein length
Met1-Met294
Predicted molecular weight
34.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8B9Q8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phosphoprotein, Protein P, P
Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus., PMID:37993464
Specific Residues in the C-Terminal Domain of the Human Metapneumovirus Phosphoprotein Are Indispensable for Formation of Viral Replication Centers and Regulation of the Function of the Viral Polymerase Complex., PMID:37092993
Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies., PMID:35536005
Interactions between the Nucleoprotein and the Phosphoprotein of Pneumoviruses: Structural Insight for Rational Design of Antivirals., PMID:34960719
Characterization of the Interaction Domains between the Phosphoprotein and the Nucleoprotein of Human Metapneumovirus., PMID:34730389
Induction of Protective Immunity by a Single Low Dose of a Master Cell Bank cGMP-rBCG-P Vaccine Against the Human Metapneumovirus in Mice., PMID:34268134
Structures of the Mononegavirales Polymerases., PMID:32847861
Respiratory Syncytial Virus and Human Metapneumovirus Infections in Three-Dimensional Human Airway Tissues Expose an Interesting Dichotomy in Viral Replication, Spread, and Inhibition by Neutralizing Antibodies., PMID:32759319
N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I., PMID:32015498
Structure of the human metapneumovirus polymerase phosphoprotein complex., PMID:31698413
Biochemical characterization of the respiratory syncytial virus N0-P complex in solution., PMID:30626736
Recombinant BCG Vaccines Reduce Pneumovirus-Caused Airway Pathology by Inducing Protective Humoral Immunity., PMID:30581437
RNAi Targeting of Human Metapneumovirus P and N Genes Inhibits Viral Growth., PMID:30145592
Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering., PMID:29093501
Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription., PMID:28978704
Human Metapneumovirus M2-2 Protein Acts as a Negative Regulator of Alpha Interferon Production by Plasmacytoid Dendritic Cells., PMID:28768858
Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread., PMID:27683250
Role of hydrogen sulfide in paramyxovirus infections., PMID:25740991
Impact and regulation of lambda interferon response in human metapneumovirus infection., PMID:25355870
IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice., PMID:24726644
Immunization with a recombinant bacillus Calmette-Guerin strain confers protective Th1 immunity against the human metapneumovirus., PMID:24319265
Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus., PMID:24224051
The characterization of monoclonal antibodies to human metapneumovirus and the detection of multiple forms of the virus nucleoprotein and phosphoprotein., PMID:22585723
Recombinant expression and immunological characterisation of proteins derived from human metapneumovirus., PMID:21920812
Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein., PMID:20042593
Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation., PMID:18931065
Chimeric recombinant human metapneumoviruses with the nucleoprotein or phosphoprotein open reading frame replaced by that of avian metapneumovirus exhibit improved growth in vitro and attenuation in vivo., PMID:16306583
Use of the P gene to genotype human metapneumovirus identifies 4 viral subtypes., PMID:15529254
High genetic diversity of the attachment (G) protein of human metapneumovirus., PMID:15297475
Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus., PMID:12904367
Sequence analysis of the N, P, M and F genes of Canadian human metapneumovirus strains., PMID:12727342
Subtype B avian metapneumovirus resembles subtype A more closely than subtype C or human metapneumovirus with respect to the phosphoprotein, and second matrix and small hydrophobic proteins., PMID:12686426
For research use only. Not for human or drug use.
