Catalog No.
DHC15401
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
PLAP-1, ALPP, Placental alkaline phosphatase 1, PLAP, Alkaline phosphatase Regan isozyme, Alkaline phosphatase, placental type, Placental alkaline phosphatase-like, PLAP-like, ALPPL2, Alkaline phosphatase, placental-like, ALP-1, GCAP, Germ cell alkaline phosphatase, ALPPL, Alkaline phosphatase Nagao isozyme, ALPG, Alkaline phosphatase, germ cell type
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05187, P10696
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SGN-ALPV
Affinity enrichment of placental extracellular vesicles from minimally processed maternal plasma with magnetic nanowires., PMID:40172922
Altered Spike Immunoglobulin G Fc N-Linked Glycans Are Associated With Hyperinflammatory State in Adult Coronavirus Disease 2019 and Multisystem Inflammatory Syndrome in Children., PMID:39494457
Customizing EV-CATCHER to Purify Placental Extracellular Vesicles from Maternal Plasma to Detect Placental Pathologies., PMID:38791142
Transcriptome and chromatin landscape changes associated with trastuzumab resistance in HER2+ breast cancer cells., PMID:34224831
SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models., PMID:33910981
PLAP -CAR T cells mediate high specific cytotoxicity against colon cancer cells., PMID:32472757
Immunolocalization of DMRTB1 in human testis with normal and impaired spermatogenesis., PMID:30920770
Placental exosomes profile in maternal and fetal circulation in intrauterine growth restriction - Liquid biopsies to monitoring fetal growth., PMID:29626979
Membrane Fusion Mediated Targeted Cytosolic Drug Delivery Through scFv Engineered Sendai Viral Envelopes., PMID:25941820
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer., PMID:25710561
Ectoenzyme switches the surface of magnetic nanoparticles for selective binding of cancer cells., PMID:25586118
Nature of immobilization surface affects antibody specificity to placental alkaline phosphatase., PMID:25321174
A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer., PMID:24247025
A study of α5 chain of collagen IV, caldesmon, placental alkaline phosphatase and smoothelin as immunohistochemical markers of gastrointestinal smooth muscle neoplasms., PMID:24043717
Identification of a region within the placental alkaline phosphatase mRNA that mediates p180-dependent targeting to the endoplasmic reticulum., PMID:24019514
Injured kidney endothelium is only marginally repopulated by cells of extrarenal origin., PMID:23884147
[Primary seminoma in external auditory canal: report of a case]., PMID:23611279
A highly sensitive and specific chemiluminescent enzyme immunoassay for placental alkaline phosphatase in the cerebrospinal fluid of patients with intracranial germinomas., PMID:23429277
Expression of an antibody-enzyme complex by the L-chain fusion method., PMID:23415663
Comparison of candidate serologic markers for type I and type II ovarian cancer., PMID:21704359
Indication of intraoperative immunohistochemistry for accurate pathological diagnosis of brain tumors., PMID:21416251
Specificity and sensitivity of differentiation antigens in superficial soft tissue tumors: comparison of SMA, calponin, H-caldesmon, C-kit, PLAP and HPL., PMID:21033622
Canine classical seminoma: a specific malignant type with human classifications is highly correlated with tumor angiogenesis., PMID:20509912
Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina., PMID:20394057
Trans-splicing as a novel method to rapidly produce antibody fusion proteins., PMID:19409879
Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)., PMID:18700980
Classical and spermatocytic seminoma in the dog: histochemical and immunohistochemical findings., PMID:17629966
Construction and purification of a covalently linked divalent tandem single-chain Fv antibody against placental alkaline phosphatase., PMID:17044780
Mammalian alkaline phosphatase catalysis requires active site structure stabilization via the N-terminal amino acid microenvironment., PMID:16893177
MR imaging of lineage-restricted neural precursors following transplantation into the adult spinal cord., PMID:16764862
A phage antibody to the active site of human placental alkaline phosphatase with higher affinity to the enzyme-substrate complex., PMID:16600380
Raft partitioning and dynamic behavior of human placental alkaline phosphatase in giant unilamellar vesicles., PMID:15895991
Double immunolabeling by the RBM and the PLAP markers for identifying intratubular (in situ) germ cell neoplasia of the testis., PMID:12598912
Preparation and functional characterization of villous cytotrophoblasts free of syncytial fragments., PMID:11945084
Isolation of antibody to human placental alkaline phosphatase (PLAP) from extracts of human placentae., PMID:11506080
Efficient gene transfer in mouse neural precursors with a bicistronic retroviral vector., PMID:11494355
Mapping a heparin binding site on ErbB-3 epidermal growth factor receptor., PMID:11322758
Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane., PMID:10980698
Passive immunotherapy of mice bearing Ehrlich ascites tumor expressing human, membrane-bound placental alkaline phosphatase., PMID:10754465
Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells., PMID:10704449
Association of stomatin with lipid-protein complexes in the plasma membrane and the endocytic compartment., PMID:10604657
HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism., PMID:9529327
Immunohistochemistry in the diagnosis of the gestational trophoblastic disease., PMID:8906012
[Detection of placental alkaline phosphatase in ovarian cancer]., PMID:8758806
Bispecific antibody-mediated lysis of placental and germ cell alkaline phosphatase targeted solid tumors in immunocompetent mice., PMID:7671251
Use of a novel human immunodeficiency virus type 1 reporter virus expressing human placental alkaline phosphatase to detect an alternative viral receptor., PMID:7769729
Maternal serum placental alkaline phosphatase level and risk for preterm delivery., PMID:7631677
Separation of the two most closely related isoenzymes of alkaline phosphatase by two-dimensional electrophoresis., PMID:7498177
Targeting of tumours with murine and reshaped human monoclonal antibodies against placental alkaline phosphatase: immunolocalisation, pharmacokinetics and immune response., PMID:7880616
Placental serum alkaline phosphatase, defined by monoclonal antibody C2, in non-malignant diseases and in non-germinal tumors., PMID:8138665
For research use only. Not for human or drug use.
