Comparative evaluation of antitumor effects of TNF superfamily costimulatory ligands delivered by mesenchymal stem cells., PMID:37995568
Lung transcriptomics of K18-hACE2 mice highlights mechanisms and genes involved in the MVA-S vaccine-mediated immune response and protection against SARS-CoV-2 infection., PMID:37992765
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy., PMID:37337107
Blocking the GITR-GITRL pathway to overcome resistance to therapy in sarcomatoid malignant pleural mesothelioma., PMID:34312483
Immune-related genes and gene sets for predicting the response to anti-programmed death 1 therapy in patients with primary or metastatic non-small cell lung cancer., PMID:34084219
Characterization of the Cell Surface Phenotype and Regulatory Activity of B-Cell IgD Low (BDL) Regulatory B Cells., PMID:33479901
Induction of Antigen-Independent Proliferation of Regulatory T-Cells by TNF Superfamily Ligands OX40L and GITRL., PMID:33185867
Effects of protein-protein interface disruptors at the ligand of the glucocorticoid-induced tumor necrosis factor receptor-related gene (GITR)., PMID:32569630
HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality., PMID:31324216
Mature IgDlow/- B cells maintain tolerance by promoting regulatory T cell homeostasis., PMID:30643147
Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases., PMID:28275260
A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist., PMID:28069723
Blockade of Glucocorticoid-Induced Tumor Necrosis Factor-Receptor-Related Protein Signaling Ameliorates Murine Collagen-Induced Arthritis by Modulating Follicular Helper T Cells., PMID:27106763
GITRL is associated with increased autoantibody production in patients with rheumatoid arthritis., PMID:27098050
GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis., PMID:26657118
Authentic GITR Signaling Fails To Induce Tumor Regression unless Foxp3+ Regulatory T Cells Are Depleted., PMID:26423152
Expression and purification of the mGITR-Fc fusion protein and its effect on CD4⁺ T cells and dendritic cells in vitro., PMID:26018202
Macrophage-T cell interactions mediate neuropathic pain through the glucocorticoid-induced tumor necrosis factor ligand system., PMID:25787078
GITRL as a genetic adjuvant enhances enterovirus 71 VP1 DNA vaccine immunogenicity., PMID:25772201
Porphyromonas gingivalis B cell Antigen Epitope Vaccine, pIRES-ragB'-mGITRL, Promoted RagB-Specific Antibody Production and Tfh Cells Expansion., PMID:25689343
Anti-GITR agonist therapy intrinsically enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus (LCMV), thereby circumventing LCMV-induced downregulation of costimulatory GITR ligand on APC., PMID:25281716
Secreted and transmembrane 1A is a novel co-stimulatory ligand., PMID:24039998
Enhancing specific-antibody production to the ragB vaccine with GITRL that expand Tfh, IFN-γ(+) T cells and attenuates Porphyromonas gingivalis infection in mice., PMID:23560053
Correlation of circulating glucocorticoid-induced TNFR-related protein ligand levels with disease activity in patients with systemic lupus erythematosus., PMID:23251213
[Construction, expression and immunogenicity of EV71 multiepitope-mGITRL eukaryotic plasmid]., PMID:22863582
An in vivo immunotherapy screen of costimulatory molecules identifies Fc-OX40L as a potent reagent for the treatment of established murine gliomas., PMID:22781551
[Construction of eukaryotic co-expression vector of Porphyromonas gingivalis outer membrane protein ragB and glucocorticoid-induced tumor necrosis factor receptor ligand (GITRL) and its immunogenic analysis]., PMID:22691349
Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF-α: implications for atopic dermatitis., PMID:22417213
A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand., PMID:22368274
Pharmacological modulation of GITRL/GITR system: therapeutic perspectives., PMID:22029729
Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells., PMID:22028176
HLA-G level on monocytoid dendritic cells correlates with regulatory T-cell Foxp3 expression in liver transplant tolerance., PMID:21423069
Dendritic cells engineered to express GITRL enhance therapeutic immunity in murine Lewis lung carcinoma., PMID:21186078
Gene expression analysis of HUVEC in response to TF-binding., PMID:21186047
GITR ligand-mediated local expansion of regulatory T cells and immune privilege of corneal allografts., PMID:20702832
Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival., PMID:20148423
Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice., PMID:20107429
Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target., PMID:19936238
[Expression and analysis of the extracellular domain of human glucocorticoid-induced tumor necrosis factor receptor ligand in Escherichia coli]., PMID:19670639
Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours., PMID:19604302
Trimer stabilization, oligomerization, and antibody-mediated cell surface immobilization improve the activity of soluble trimers of CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand., PMID:19596991
Interaction of T-cell and antigen presenting cell co-stimulatory genes in childhood IgE., PMID:19574333
Regression of established AB1 murine mesothelioma induced by peritumoral injections of CpG oligodeoxynucleotide either alone or in combination with poly(I:C) and CD40 ligand plasmid DNA., PMID:19550243
Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation., PMID:19536139
The glucocorticoid-induced TNF receptor-related protein (GITR)-GITR ligand pathway acts as a mediator of cutaneous dendritic cell migration and promotes T cell-mediated acquired immunity., PMID:19234165
Co-immunization of mice with a retroviral DNA vaccine and GITRL-encoding plasmid augments vaccine-induced protection against retrovirus infection., PMID:19115935
Localized expression of GITR-L in the tumor microenvironment promotes CD8+ T cell dependent anti-tumor immunity., PMID:19018533
Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta., PMID:18924213
GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells., PMID:18346459
Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer., PMID:18223234
For research use only. Not for human or drug use.
