Catalog No.
PHF11401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ADAR/IFI4 (Asn503-Val885).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Double-stranded RNA-specific adenosine deaminase,G1P1,IFI-4,ADAR,K88DSRBP,DRADA,ADAR1,IFI4,Interferon-inducible protein 4,p136,136 kDa double-stranded RNA-binding protein,DSRAD
Purification
Purified by antigen affinity column.
Accession
P55265
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
3'UTR RNA editing driven by ADAR1 modulates MDM2 expression in breast cancer cells., PMID:40381037
ADARp110 promotes hepatocellular carcinoma progression via stabilization of CD24 mRNA., PMID:39808660
Predicting graft survival in paediatric kidney transplant recipients using machine learning., PMID:39150523
Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer's disease by capillary western blotting., PMID:38299128
Immunologic and Protective Properties of Subunit- vs. Whole Toxoid-Derived Anti-Botulinum Equine Antitoxin., PMID:36146601
IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation., PMID:35935998
Single-cell RNA Sequencing Analysis Reveals New Immune Disorder Complexities in Hypersplenism., PMID:35865544
Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells., PMID:35731225
Not "If", but "When" and "How": Testing Antibody-Drug Conjugates in Patients with Non-muscle-invasive Bladder Cancer., PMID:34838351
Evaluation of a downstream process for the recovery and concentration of a Cell-Culture-Derived rVSV-Spike COVID-19 vaccine candidate., PMID:34756612
Host Immune Response Driving SARS-CoV-2 Evolution., PMID:32992592
Clinical and serological features of dermatomyositis and systemic lupus erythematosus patients with autoantibodies to ADAR1., PMID:32907776
Host immune response driving SARS-CoV-2 evolution., PMID:32839723
RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia., PMID:32728184
MS2-TRIBE Evaluates Both Protein-RNA Interactions and Nuclear Organization of Transcription by RNA Editing., PMID:32674054
RNA editing as a therapeutic approach for retinal gene therapy requiring long coding sequences., PMID:31991730
Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies., PMID:31658304
RNA editing in the forefront of epitranscriptomics and human health., PMID:31547885
AKT-dependent phosphorylation of the adenosine deaminases ADAR-1 and -2 inhibits deaminase activity., PMID:31095429
Comparative safety and effectiveness of tumor necrosis factor α antagonists and vedolizumab in elderly IBD patients: a multicentre study., PMID:30773667
Illuminating spatial A-to-I RNA editing signatures within the Drosophila brain., PMID:30659150
APOBEC and ADAR deaminases may cause many single nucleotide polymorphisms curated in the OMIM database., PMID:29957488
ADAR1-mediated regulation of melanoma invasion., PMID:29855470
Integrative Analysis of Immunological Data to Explore Chronic Immune T-Cell Activation in Successfully Treated HIV Patients., PMID:28046052
REPLY: Treatment with oxLDL antibody reduces cathepsin S expression in atherosclerosis via down-regulating ADAR1-mediated RNA editing., PMID:28003044
Treatment with oxLDL antibody reduces cathepsin S expression in atherosclerosis via down-regulating ADAR1-mediated RNA editing., PMID:27956316
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation., PMID:27595325
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins., PMID:27040499
The Importance of Intestinal Eotaxin-1 in Inflammatory Bowel Disease: New Insights and Possible Therapeutic Implications., PMID:26874691
A Phase III Study of Balugrastim Versus Pegfilgrastim in Breast Cancer Patients Receiving Chemotherapy With Doxorubicin and Docetaxel., PMID:26668251
A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme., PMID:26338962
Single nucleotide polymorphisms/haplotypes associated with multiple rubella-specific immune response outcomes post-MMR immunization in healthy children., PMID:26329766
Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-Controlled Trial., PMID:25876706
Stability of the parainfluenza virus 5 genome revealed by deep sequencing of strains isolated from different hosts and following passage in cell culture., PMID:24453358
Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study., PMID:24183309
Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells., PMID:22236001
Genetic polymorphisms in host antiviral genes: associations with humoral and cellular immunity to measles vaccine., PMID:21939710
Non-ST Elevation Myocardial Infraction after High Dose Intravenous Immunoglobulin Infusion., PMID:20182639
Cholestatic jaundice induced by atorvastatin: a possible association with antimitochondrial antibodies., PMID:19911499
Adalimumab-induced autoimmune hepatitis., PMID:19593165
A universal epitope-based influenza vaccine and its efficacy against H5N1., PMID:19356612
ADAR1 and ADAR2 expression and editing activity during forebrain development., PMID:19325227
Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs., PMID:18515351
ICAM1 and VCAM1 polymorphisms, coronary artery calcium, and circulating levels of soluble ICAM-1: the multi-ethnic study of atherosclerosis (MESA)., PMID:18420209
A method to find tissue-specific novel sites of selective adenosine deamination., PMID:16257978
Identification of new targets of Drosophila pre-mRNA adenosine deaminase., PMID:15522950
Contribution of immunological memory to protective immunity conferred by a Bacillus anthracis protective antigen-based vaccine., PMID:15155654
Characterization and application of Raman labels for confocal Raman microspectroscopic detection of cellular proteins in single cells., PMID:14596828
Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3., PMID:12842902
A model for the generation of multiple A to G transitions in the human respiratory syncytial virus genome: predicted RNA secondary structures as substrates for adenosine deaminases that act on RNA., PMID:12029160
For research use only. Not for human or drug use.
