Catalog No.
PHF11001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CASP9/Caspase 9 (Lys100-Thr270).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CASP9,ICE-like apoptotic protease 6,Apoptotic protease Mch-6,APAF-3,CASP-9,MCH6,Apoptotic protease-activating factor 3,Caspase-9,ICE-LAP6
Purification
Purified by antigen affinity column.
Accession
P55211
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting., PMID:38767611
Variants of the CASP9 gene as candidate markers for primary response to anti-TNF therapy in Crohn's disease patients., PMID:37658984
The Qi Yin San Liang San decoction enhances anti-CD19 CAR-T cell function in the treatment of B-cell lymphomas., PMID:37657771
Mucin 1 as a Molecular Target of a Novel Diisoquinoline Derivative Combined with Anti-MUC1 Antibody in AGS Gastric Cancer Cells., PMID:34770912
LOX-1 Regulates Neutrophil Apoptosis and Fungal Load in A. Fumigatus Keratitis., PMID:34264144
Anti-cancer effect of combined action of anti-MUC1 and rosmarinic acid in AGS gastric cancer cells., PMID:33930385
Enhanced Caspase-Mediated Abrogation of Autophagy by Temozolomide-Loaded and Panitumumab-Conjugated Poly(lactic-co-glycolic acid) Nanoparticles in Epidermal Growth Factor Receptor Overexpressing Glioblastoma Cells., PMID:33079558
The soluble VEGF receptor sFlt-1 contributes to endothelial dysfunction in IgA nephropathy., PMID:32790760
The expression profiles of apoptosis-related genes induced usnic acid in SK-BR-3 breast cancer cell., PMID:32508146
Occurrence of Retinal Ganglion Cell Loss via Autophagy and Apoptotic Pathways in an Autoimmune Glaucoma Model., PMID:31935132
RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones., PMID:30850627
Ginkgetin inhibits proliferation of human leukemia cells via the TNF-α signaling pathway., PMID:28902633
TNF-α Mediates the Intrinsic and Extrinsic Pathway in Propofol-Induced Neuronal Apoptosis Via PI3K/Akt Signaling Pathway in Rat Prefrontal Cortical Neurons., PMID:28540664
Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment., PMID:27886059
Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors., PMID:27548616
A benchmark testing ground for integrating homology modeling and protein docking., PMID:27172383
Casp8p41 and HIV., PMID:26309081
Apoptosis inhibitor TRIAP1 is a novel effector of drug resistance., PMID:25998939
Synergistic induction of apoptosis by mapatumumab and anthracyclines in human bladder cancer cells., PMID:25483927
The decreased expression of thioredoxin-1 in brain of mice with experimental autoimmune myasthenia gravis., PMID:24878227
Anti-cadherin-17 antibody modulates beta-catenin signaling and tumorigenicity of hepatocellular carcinoma., PMID:24039755
Tumor necrosis factor-α mediates JNK activation response to intestinal ischemia-reperfusion injury., PMID:23946597
The BH3-only protein Bim(L) overrides Bcl-2-mediated apoptosis resistance in melanoma cells., PMID:23402819
Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression., PMID:23384561
Neural nitric oxide synthase participates in pemphigus vulgaris acantholysis through upregulation of Rous sarcoma, mammalian target of rapamycin and focal adhesion kinase., PMID:23362871
Potential apoptotic effect of ultraviolet-A irradiation during cross-linking: a study on ex vivo cultivated limbal epithelial cells., PMID:22942165
[Effects of neuroactive steroid allopregnanolone on the damage of cortical neurons]., PMID:21845865
ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists., PMID:21695558
Inhibition of cellular FLICE-like inhibitory protein abolishes insensitivity to interferon-α and death receptor stimulation in resistant variants of the human U937 cell line., PMID:21562857
Anti-cancer activity of anti-p185HER-2 ricin A chain immunotoxin on gastric cancer cells., PMID:20594254
Fas apoptosis inhibitory molecule regulates T cell receptor-mediated apoptosis of thymocytes by modulating Akt activation and Nur77 expression., PMID:20178987
Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases., PMID:19911005
Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells., PMID:19318910
The oral anti-diabetic agent, gliclazide, inhibits oxidized LDL-mediated LOX-1 expression, metalloproteinase-9 secretion and apoptosis in human aortic endothelial cells., PMID:18801483
Pathways involved in testicular germ cell apoptosis in immature rats after FSH suppression., PMID:18372230
Photodynamic therapy induces caspase-dependent apoptosis in rat CNV model., PMID:17898299
Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells., PMID:17452973
Anaplasma phagocytophilum delays spontaneous human neutrophil apoptosis by modulation of multiple apoptotic pathways., PMID:16922860
Chlamydia heat shock protein 60 induces trophoblast apoptosis through TLR4., PMID:16818785
Involvement of caspase 1 and its activator Ipaf upstream of mitochondrial events in apoptosis., PMID:16817903
Pioglitazone induces apoptosis of macrophages in human adipose tissue., PMID:16799131
Autoantibodies from Sjögren's syndrome induce activation of both the intrinsic and extrinsic apoptotic pathways in human salivary gland cell line A-253., PMID:16797160
Activation of caspases in human spermatozoa during cryopreservation--an immunoblot study., PMID:16732410
Cardiomyoblast apoptosis induced by insulin-like growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II., PMID:16699953
Activation of peroxisome proliferator-activated receptor alpha enhances apoptosis in the mouse liver., PMID:16687391
Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine., PMID:16630893
Glucocorticoid modulatory element-binding protein 1 binds to initiator procaspases and inhibits ischemia-induced apoptosis and neuronal injury., PMID:16497673
Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes., PMID:16449966
Protection of human and murine hepatocytes against Fas-induced death by transferrin and iron., PMID:16374550
Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers., PMID:16322111
For research use only. Not for human or drug use.
