Anti-CASP7 Polyclonal Antibody

Catalog No.

PHF10901

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CASP7 (Ala24-Asp198).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CASP7,ICE-LAP3,CASP-7,MCH3,Caspase-7,CMH-1,ICE-like apoptotic protease 3,Apoptotic protease Mch-3

Purification

Purified by antigen affinity column.

Accession

P55210

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

The Qi Yin San Liang San decoction enhances anti-CD19 CAR-T cell function in the treatment of B-cell lymphomas., PMID:37657771

Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity., PMID:31940267

Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways., PMID:31730855

Acute pulmonary effects of aerosolized nicotine., PMID:30358437

G-quartet oligonucleotide mediated delivery of functional X-linked inhibitor of apoptosis protein into retinal cells following intravitreal injection., PMID:29864441

Zoledronic acid overcomes chemoresistance by sensitizing cancer stem cells to apoptosis., PMID:29300112

Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model., PMID:28783166

Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia., PMID:27283740

Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death., PMID:27133385

Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 and -7-dependent., PMID:26504199

Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice., PMID:25366368

Targeted elimination of activated hepatic stellate cells by an anti-epidermal growth factor-receptor single chain fragment variable antibody-tumor necrosis factor-related apoptosis-inducing ligand (scFv425-sTRAIL)., PMID:25088657

Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis., PMID:24574456

Myocilin regulates cell proliferation and survival., PMID:24563482

Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock., PMID:24456467

Loss of caspase 7 expression is associated with poor prognosis in renal cell carcinoma clear cell subtype., PMID:23920448

Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics., PMID:23867459

BH3 mimetics reduce adhesion and migration of hepatoblastoma and hepatocellular carcinoma cells., PMID:23416067

REST is up-regulated by epidermal growth factor in HeLa cells and inhibits apoptosis by influencing histone H3 acetylation., PMID:22668508

[Role of NF-κB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells]., PMID:22340043

Staurosporine-induced differentiation of the RGC-5 cell line leads to apoptosis and cell death at the lowest differentiating concentration., PMID:22222923

HDAC inhibitors potentiate the apoptotic effect of enzastaurin in lymphoma cells., PMID:21667043

Amyloid beta-mediated cell death of cultured hippocampal neurons reveals extensive Tau fragmentation without increased full-length tau phosphorylation., PMID:21482827

Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner., PMID:20872776

ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis., PMID:20213810

Chemotherapy-induced thrombin generation via procoagulant endothelial microparticles is independent of tissue factor activity., PMID:17922809

Secretory phospholipase A2 induces apoptosis through TNF-alpha and cytochrome c-mediated caspase cascade in murine macrophage RAW 264.7 cells., PMID:16564042

Glucocorticoid modulatory element-binding protein 1 binds to initiator procaspases and inhibits ischemia-induced apoptosis and neuronal injury., PMID:16497673

Relationship between SUMO-1 modification of caspase-7 and its nuclear localization in human neuronal cells., PMID:16378684

Wnt/beta-catenin signaling mediates antineoplastic effects of imatinib mesylate (gleevec) in anaplastic thyroid cancer., PMID:16263821

Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker., PMID:15904507

A novel caspase-7 specific monoclonal antibody., PMID:15849872

p53 potentiation of tumor cell susceptibility to CTL involves Fas and mitochondrial pathways., PMID:15634909

Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling., PMID:15623759

Cleavage of calnexin caused by apoptotic stimuli: implication for the regulation of apoptosis., PMID:15598898

Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells., PMID:15563545

Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone hsp70., PMID:15544164

Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation., PMID:15469933

Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells., PMID:15283467

Keratin 8/18 breakdown and reorganization during apoptosis., PMID:15194421

Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin., PMID:14695155

Teratogen-induced activation of caspase-6 and caspase-7 in early postimplantation mouse embryos., PMID:14686614

Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1., PMID:12867998

Ribavirin and alpha interferon enhance death receptor-mediated apoptosis and caspase activation in human hepatoma cells., PMID:12760867

The p54 cleaved form of the tyrosine kinase Lyn generated by caspases during BCR-induced cell death in B lymphoma acts as a negative regulator of apoptosis., PMID:12586738

Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis., PMID:12432255

Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway., PMID:12181741

Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells., PMID:11937545

Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases., PMID:11801463

Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short)., PMID:11585748

Document Download

Anti-CASP7 Polyclonal Antibody.pdf