Anti-HMGA2 Polyclonal Antibody

Catalog No.

PHE96301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HMGA2 (Met1-Asp109).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

HMGA2,HMGIC,High mobility group protein HMGI-C,High mobility group AT-hook protein 2

Purification

Purified by antigen affinity column.

Accession

P52926

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration., PMID:39032683

Novel Approaches to Possible Targeted Therapies and Prophylaxis of Uterine Fibroids., PMID:37987267

[Fibrocartilaginous lipoma: a clinicopathological analysis of six cases]., PMID:37527988

Updated Salivary Gland Immunohistochemistry: A Review., PMID:37074867

Sex Influences Age-Related Changes in Natural Antibodies and CD5+ B-1 Cells., PMID:35256511

Breast hamartoma: reassessment of an under-recognised breast lesion., PMID:34403159

Metastatic malignant melanoma mimicking a salivary gland basaloid neoplasm after treatment with nivolumab., PMID:34174024

Let-7, Lin28 and Hmga2 Expression in Ciliary Epithelium and Retinal Progenitor Cells., PMID:33749722

BOC-PLAG1, a new fusion gene of pleomorphic adenoma: Identified in a fine-needle aspirate by RNA next-generation sequencing., PMID:33710800

Proteomic analysis of radio-resistant breast cancer xenografts: Increased TGF-β signaling and metabolism., PMID:33325135

Ultrastructural localization of the likely mechanoelectrical transduction channel protein, transmembrane-like channel 1 (TMC1) during development of cochlear hair cells., PMID:30718571

Radio resistance in breast cancer cells is mediated through TGF-β signalling, hybrid epithelial-mesenchymal phenotype and cancer stem cells., PMID:30579251

High-grade myoepithelial carcinoma can show histologically undifferentiated/anaplastic features., PMID:30236544

Targeting HMGA protein inhibits retinoblastoma cell proliferation., PMID:35548247

Application of microRNA Targeted 3'UTRs to Repress DHFR Selection Marker Expression for Development of Recombinant Antibody Expressing CHO Cell Pools., PMID:29981248

Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15., PMID:29069081

JAK2V617F influences epigenomic changes in myeloproliferative neoplasms., PMID:29066347

MiR-let-7a regulates anti-citrullinated protein antibody-induced macrophage activation and correlates with the development of experimental rheumatoid arthritis., PMID:28802150

The HMGA gene family in chordates: evolutionary perspectives from amphioxus., PMID:28474175

Complementary actions of dopamine D2 receptor agonist and anti-vegf therapy on tumoral vessel normalization in a transgenic mouse model., PMID:28152577

HMGA2 expression distinguishes between different types of postpubertal testicular germ cell tumour., PMID:27499908

Usefulness of translocation-associated immunohistochemical stains in the fine-needle aspiration diagnosis of salivary gland neoplasms., PMID:26882287

A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer., PMID:26695438

Pancreatic cyst fluid concentration of high-mobility group A2 protein acts as a differential biomarker of dysplasia in intraductal papillary mucinous neoplasm., PMID:26408423

Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins., PMID:26373678

Lipoblastoma-like tumor of the vulva: further characterization in 8 new cases., PMID:25929353

MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2., PMID:25725129

Myogenin, AP2β, NOS-1, and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma: a report from the soft tissue sarcoma committee of the children's oncology group., PMID:24618610

Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: an overview., PMID:23359388

High mobility group AT-hook 2 is overexpressed in hepatoblastoma., PMID:23134771

[Paroxysmal nocturnal hemoglobinuria]., PMID:22374521

HMGA2 is commonly expressed in uterine serous carcinomas and is a useful adjunct to diagnosis., PMID:22250726

New prognostic markers and potential therapeutic targets in human testicular germ cell tumors., PMID:22050751

Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation., PMID:21898684

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers., PMID:21533284

Aberrant PLAG1 expression in pleomorphic adenomas of the salivary gland: a molecular genetic and immunohistochemical study., PMID:21394649

Value and limitation of immunohistochemical expression of HMGA2 in mesenchymal tumors: about a series of 1052 cases., PMID:20834238

[Pathophysiology and treatment of paroxysmal nocturnal hemoglobinuria (PNH)--recent advances]., PMID:20068274

Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis., PMID:19346081

Identification of mesenchymal stem cell (MSC)-transcription factors by microarray and knockdown analyses, and signature molecule-marked MSC in bone marrow by immunohistochemistry., PMID:19228201

SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome., PMID:18413806

Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis., PMID:17332316

Differential expression of HMGA1 and HMGA2 in dermatofibroma and dermatofibrosarcoma protuberans: potential diagnostic applications, and comparison with histologic findings, CD34, and factor XIIIa immunoreactivity., PMID:15249855

HMGA1 and HMGA2 protein expression in mouse spermatogenesis., PMID:12032866

Recent advances in immunohistochemistry in gynaecological pathology., PMID:11943015

Expression of HMGI-C and HMGI(Y) in ordinary lipoma and atypical lipomatous tumors: immunohistochemical reactivity correlates with karyotypic alterations., PMID:9212729

Human colorectal carcinomas express high levels of high mobility group HMGI(Y) proteins., PMID:8620511

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