Catalog No.
PHJ35501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DVL3 (Asn246-Lys335).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Dishevelled-3, DVL3, Segment polarity protein dishevelled homolog DVL-3, DSH homolog 3, KIAA0208
Purification
Purified by antigen affinity column.
Accession
Q92997
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia., PMID:27086035
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling., PMID:27191743
Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling., PMID:25168481
The functions of maternal Dishevelled 2 and 3 in the early Xenopus embryo., PMID:21618643
Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression., PMID:18692936
Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3., PMID:18093802
Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease., PMID:17671721
WNT/PCP signaling pathway and human cancer (review)., PMID:16273260
Efficacy of Wnt-1 monoclonal antibody in sarcoma cells., PMID:15913453
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability., PMID:10330181