Catalog No.
PHE91901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DGKE (Leu243-Gly502).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DGKE,Diglyceride kinase epsilon,DAG kinase epsilon,DGK-epsilon,Diacylglycerol kinase epsilon,DAGK5
Purification
Purified by antigen affinity column.
Accession
P52429
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Pregnancy-related Thrombotic Microangiopathy has a spectrum of underlying causes., PMID:40306205
Adolescence-onset atypical hemolytic uremic syndrome: is it different from infant-onset?, PMID:38704765
Management of pediatric hemolytic uremic syndrome., PMID:38523374
CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome., PMID:36755127
Variants in complement genes are uncommon in patients with anti-factor H autoantibody-associated atypical hemolytic uremic syndrome., PMID:36622444
Pediatric Atypical Hemolytic Uremic Syndrome Advances., PMID:34944087
Blockade of the Terminal Complement Cascade Using Ravulizumab in a Pediatric Patient With Anti-complement Factor H Autoantibody-Associated aHUS: A Case Report and Literature Review., PMID:34912617
A patient with a homozygous diacylglycerol kinase epsilon (DGKE) gene mutation with atypical haemolytic uraemic syndrome and low C3 responded well to eculizumab: a case report., PMID:33879077
Atypical hemolytic uremic syndrome due to DGKE mutation and response to eculizumab: lessons for the clinical nephrologist., PMID:33751496
Molecular basis and outcomes of atypical haemolytic uraemic syndrome in Czech children., PMID:32424742
Eculizumab treatment of thrombotic microangiopathy in a patient with ulcerative colitis., PMID:31612381
Treatment of hemolytic uremic syndrome related to Bordetella pertussis infection -is plasma exchange or eculizumab use necessary?, PMID:30558570
Atypical presentation of atypical haemolytic uraemic syndrome., PMID:29440240
Glucose-6-Phosphate Dehydrogenase Deficiency Mimicking Atypical Hemolytic Uremic Syndrome., PMID:29248304
Targeted exome sequencing in anti-factor H antibody negative HUS reveals multiple variations., PMID:28939980
Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis., PMID:27146825
[Genetics of aHUS and transplant recurrence]., PMID:26479051
Atypical haemolytic uraemic syndrome in a Japanese patient with DGKE genetic mutations., PMID:26018111
[Atypical HUS caused by complement-related abnormalities]., PMID:25765799
Complement mutations in diacylglycerol kinase-ε-associated atypical hemolytic uremic syndrome., PMID:25135762
Complement therapy in atypical haemolytic uraemic syndrome (aHUS)., PMID:23810412
Complement activation in diseases presenting with thrombotic microangiopathy., PMID:23743117
[Pathophysiology of atypical hemolytic uremic syndrome. Ten years of progress, from laboratory to patient]., PMID:24594571