Catalog No.
PHG55401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TCIRG1 (Met1-Glu385).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TCIRG1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3, V-ATPase 116 kDa subunit a3, V-type proton ATPase 116 kDa subunit a3, ATP6V0A3, ATP6N1C, Osteoclastic proton pump 116 kDa subunit, TIRC7, T-cell immune response cDNA7 protein, T-cell immune regulator 1, OC-116 kDa, OC116
Purification
Purified by antigen affinity column.
Accession
Q13488
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Glioblastoma TCGA Mesenchymal and IGS 23 Tumors are Identifiable by IHC and have an Immune-phenotype Indicating a Potential Benefit from Immunotherapy., PMID:32998960
TIRC7 inhibits Th1 cells by upregulating the expression of CTLA‑4 and STAT3 in mice with acute graft‑versus‑host disease., PMID:32319655
Antithymocyte globulin combined with cyclosporine A down-regulates T helper 1 cells by modulating T cell immune response cDNA 7 in aplastic anemia., PMID:26049920
TIRC7 and HLA-DR axis contributes to inflammation in multiple sclerosis., PMID:24526664
T-cell immune response cDNA 7 in allograft rejection and inflammation., PMID:17520869
TIRC7 inhibits T cell proliferation by modulation of CTLA-4 expression., PMID:17082597
Antibody targeting of TIRC7 results in significant therapeutic effects on collagen-induced arthritis in mice., PMID:16542376
TIRC7 pathway as a target for preventing allograft rejection., PMID:15883619
Monoclonal antibody specific for TIRC7 induces donor-specific anergy and prevents rejection of cardiac allografts in mice., PMID:15023142
Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein., PMID:9806637
For research use only. Not for human or drug use.
