Catalog No.
PHE84101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HCFC1 (Asn52-His258).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
CFF,VCAF,HCFC1,HCF-1,HCF1,HFC1,C1 factor,HCF,VP16 accessory protein,Host cell factor 1
Purification
Purified by antigen affinity column.
Accession
P51610
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Oct-1 transcription factor is a negative regulator of rat CYP1A1 expression via an octamer sequence in its negative regulatory element., PMID:8632766
Regulation of 3' IgH enhancers by a common set of factors, including kappa B-binding proteins., PMID:8609402
Concerted repression of an immunoglobulin heavy-chain enhancer, 3' alpha E(hs1,2)., PMID:8633077
Identification of an octamer-1 transcription factor binding site in the promoter of the mouse mu-opioid receptor gene., PMID:8858915
Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: comparison with Oct-1, Krox-20, and Pax-3., PMID:8951674
Octamer independent activation of transcription from the kappa immunoglobulin germline promoter., PMID:8972869
Decreased production of IL-2 and IFN-gamma by stimulated splenocytes from mice bearing plasma cell tumors is associated with alteration of DNA-binding factors., PMID:8982782
Involvement of an octamer-like sequence within a crucial region of the androgen-dependent Slp enhancer., PMID:9022044
Characterization of constitutive and inducible transcription factors binding to the P2 NF-AT site in the human interleukin-4 promoter., PMID:9133600
Family-specific differences in transcription efficiency of Ig heavy chain promoters., PMID:9233620
Correlation of MIB-1 antigen expression with transcription factors Skn-1, Oct-1, AP-2, and HPV type in cervical intraepithelial neoplasia., PMID:9422986
Temporal control of IgH gene expression in developing B cells by the 3' locus control region., PMID:9442395
Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription., PMID:9384588
Oct-1 enhances the in vitro replication of a mammalian autonomously replicating DNA sequence., PMID:9518258
MEF-2 and Oct-1 bind to two homologous promoter sequence elements and participate in the expression of a skeletal muscle-specific gene., PMID:9614136
Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter., PMID:9705324
Transcription factor AP1 is involved in basal and okadaic acid-stimulated activity of the human PRL promoter., PMID:9717847
Functional map of a placenta-specific enhancer of the human leukemia inhibitory factor receptor gene., PMID:9748286
Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors., PMID:10396620
The activity of the human interleukin-5 conserved lymphokine element 0 is regulated by octamer factors in human cells., PMID:10491186
Interaction and functional interference of C/EBPbeta with octamer factors in immunoglobulin gene transcription., PMID:10602039
Binding of octamer factors to a novel 3'-positive regulatory element in the mouse interleukin-5 gene., PMID:10660628
Transcription factors Oct-1 and C/EBPbeta (CCAAT/enhancer-binding protein-beta) are involved in the glutamate/nitric oxide/cyclic-guanosine 5'-monophosphate-mediated repression of mediated repression of gonadotropin-releasing hormone gene expression., PMID:10674395
Octamer transcription factor-1 enhances hepatic nuclear factor-1alpha-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter., PMID:10779377
Oct-1 specifically binds the UEF4 site of the human AP1-regulated urokinase enhancer., PMID:10951201
An essential octamer motif in the mb-1 (Igalpha) promoter., PMID:11000405
Transcriptional regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions., PMID:11126367
Cellular transcription factors that interact with p6 promoter elements of parvovirus B19., PMID:11369893
A conserved sequence block in the murine and human T cell receptor Jalpha loci interacts with developmentally regulated nucleoprotein complexes in vitro and associates with GATA-3 and octamer-binding factors in vivo., PMID:11385613
Allele-specific binding of the ubiquitous transcription factor OCT-1 to the functional single nucleotide polymorphism (SNP) sites in the tumor necrosis factor-alpha gene (TNFA) promoter., PMID:11393654
The POU homeodomain protein Oct-1 binds Cis-regulatory element essential for the human GnRH upstream promoter activity in JEG-3 cells., PMID:11397896
HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: evidence for specific promoter-enhancer interactions., PMID:11544313
Tissue-specific isoforms of the ubiquitous transcription factor Oct-1., PMID:11683265
Bob1 (OCA-B/OBF-1) differential transactivation of the B cell-specific B29 (Ig beta) and mb-1 (Ig alpha) promoters., PMID:11907094
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells., PMID:12144930
Involvement of Oct-1 in transcriptional regulation of beta-casein gene expression in mouse mammary gland., PMID:12151092
Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication., PMID:12393188
Oct-1 is involved in the transcriptional repression of the gonadotropin-releasing hormone receptor gene., PMID:12446597
Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements., PMID:12672812
Analysis of a repressor region in the human neuropeptide Y gene that binds Oct-1 and Pbx-1 in GT1-7 neurons., PMID:12878188
NF-kappa B and Oct-2 synergize to activate the human 3' Igh hs4 enhancer in B cells., PMID:14707079
B cell development and immunoglobulin transcription in Oct-1-deficient mice., PMID:14762167
Quantitative high-throughput analysis of transcription factor binding specificities., PMID:14990752
A protein sequestering system reveals control of cellular programs by the transcriptional coactivator HCF-1., PMID:15190068
E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases., PMID:19763085
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway., PMID:21285374
Novel cerebrospinal fluid and serum autoantibody targets for clinically isolated syndrome., PMID:22958230
Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus., PMID:26041297
The dystonia gene THAP1 controls DNA double-strand break repair choice., PMID:33857404
HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription., PMID:38670996