Catalog No.
PHE83501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TPMT (Leu26-His227).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Thiopurine methyltransferase,Thiopurine S-methyltransferase,TPMT
Purification
Purified by antigen affinity column.
Accession
P51580
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Review of the Regulatory Challenges of Personalized Medicine., PMID:39328627
[Benefit of therapeutic drug monitoring of immunosuppressants and immunomodulators in the management of autoimmune diseases]., PMID:35643786
Modern developments in germline pharmacogenomics for oncology prescribing., PMID:35302652
Unusual Bilateral Upper Extremity Pitting Edema in a Patient With Severe Dermatomyositis., PMID:34113527
Genetic Factors of Predisposition and Clinical Characteristics of Rheumatoid Arthritis in Russian Patients., PMID:34070522
Tests that now deserve to be more widely adopted in IBD clinical practice., PMID:32782481
NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease., PMID:32482022
Key insights from therapeutic drug monitoring in Crohn's disease patients., PMID:30892105
New Zealand Society of Gastroenterology Guidelines on Therapeutic Drug Monitoring in Inflammatory Bowel Disease., PMID:30845128
Systematic Review: Cost-effective Strategies of Optimizing Anti-tumor Necrosis and Immunomodulators in Inflammatory Bowel Disease., PMID:30689858
Azathioprine Hypersensitivity Syndrome in a Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Patients., PMID:30368003
Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis., PMID:29752633
Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody associated vasculitis: A retrospective cohort study., PMID:29630648
Relationship between Azathioprine metabolites and therapeutic efficacy in Chinese patients with neuromyelitis optica spectrum disorders., PMID:28679367
Role of Allopurinol in Optimizing Thiopurine Therapy in Patients with Autoimmune Hepatitis: A Review., PMID:28348471
Genotypes Affecting the Pharmacokinetics of Anticancer Drugs., PMID:27641154
Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016., PMID:27294413
Pharmacogenetics of inflammatory bowel disease., PMID:25521361
The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients., PMID:23932783
My treatment approach to the management of ulcerative colitis., PMID:23910410
Current relevance of pharmacogenetics in immunomodulation treatment for Crohn's disease., PMID:22741564
Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia., PMID:22484422
How are thiopurines used and monitored by Swedish gastroenterologists when treating patients with inflammatory bowel disease?, PMID:21793634
Conventional treatment in inflammatory bowel disease--recent trends. Immunosuppressants and biologic agents: should they or need they be used together? How to use immunosuppressive therapy better (and safer) tomorrow?, PMID:20117343
Variation in care in pediatric Crohn disease., PMID:19590456
Thiopurinemethyltransferase (TPMT) genotype and TPMT activity in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis: relation to azathioprine maintenance treatment and adverse effects., PMID:19366895
Dual-allele dipstick assay for genotyping single nucleotide polymorphisms by primer extension reaction., PMID:18685560
Pharmacogenetics of Crohn's disease., PMID:18597652
Pharmacogenetics in inflammatory bowel disease., PMID:16773681
Genetic testing in Crohn disease: utility in individualizing patient management., PMID:16078858
Pharmacogenetics of inflammatory bowel disease., PMID:15669633
Advances in medical therapy for Crohn's disease., PMID:12441041
Mucosal protection against sulphide: importance of the enzyme rhodanese., PMID:11788560
Pharmacokinetic considerations in the treatment of inflammatory bowel disease., PMID:11707060
Thiopurine methyltransferase regulation in rat kidney: immunoprecipitation studies., PMID:1897245
Mouse thiopurine methyltransferase pharmacogenetics: correlation of immunoreactive protein and enzymatic activity., PMID:2313588
For research use only. Not for human or drug use.
