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Anti-Phencyclidine/PCP Antibody (6B5)

Catalog #:   RGN09801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: ChEBI: 8058
Overview

Catalog No.

RGN09801

Species reactivity

General

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

PCP, Phencyclidine, 1-(1-phenylcyclohexyl)piperidine

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

ChEBI: 8058

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

6B5

Data Image
References

In vivo mapping of protein-protein interactions of schizophrenia risk factors generates an interconnected disease network., PMID:38168169

Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis., PMID:32830245

Assessment of NMDA receptor inhibition of phencyclidine analogues using a high-throughput drebrin immunocytochemical assay., PMID:31082488

Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801., PMID:30240581

Effects of selective calcium-permeable AMPA receptor blockade by IEM 1460 on psychotomimetic-induced hyperactivity in the mouse., PMID:29270730

Profiles of VGF Peptides in the Rat Brain and Their Modulations after Phencyclidine Treatment., PMID:28626390

Are therapeutic vaccines an answer to the global problem of drug and alcohol abuse?, PMID:27721531

A novel immunoassay for quantitative drug abuse screening in serum., PMID:27343723

Is immunotherapy an opportunity for effective treatment of drug addiction?, PMID:26432911

Radiolabeling of [18F]-fluoroethylnormemantine and initial in vivo evaluation of this innovative PET tracer for imaging the PCP sites of NMDA receptors., PMID:25963911

[NMDA-type glutamate receptor and schizophrenia]., PMID:25069261

Cholinergic denervation attenuates phencyclidine-induced c-fos responses in rat cortical neurons., PMID:22561731

Pharmacokinetic strategies for treatment of drug overdose and addiction., PMID:22300100

Chronic anti-phencyclidine monoclonal antibody therapy decreases phencyclidine-induced in utero fetal mortality in pregnant rats., PMID:22001428

Metabolism of bupropion by baboon hepatic and placental microsomes., PMID:21570381

The fate and function of therapeutic antiaddiction monoclonal antibodies across the reproductive cycle of rats., PMID:20962030

Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine., PMID:19400959

Generation and utilization of anti-drug monoclonal antibodies for screening of 36 drug users by dot-ELISA., PMID:19382846

A rat brain bicistronic gene with an internal ribosome entry site codes for a phencyclidine-binding protein with cytotoxic activity., PMID:19028684

Substance abuse vaccines., PMID:18991962

[Immunotherapies for drug addictions]., PMID:18551223

Pharmacokinetic approaches to treatment of drug addiction., PMID:24422652

Engineering and characterization of a mouse/human chimeric anti-phencyclidine monoclonal antibody., PMID:18068094

The future of vaccines in the management of addictive disorders., PMID:17915077

Prenatal exposure to an NMDA receptor antagonist, MK-801 reduces density of parvalbumin-immunoreactive GABAergic neurons in the medial prefrontal cortex and enhances phencyclidine-induced hyperlocomotion but not behavioral sensitization to methamphetamine in postpubertal rats., PMID:17340116

Frizzled/PCP-dependent asymmetric neuralized expression determines R3/R4 fates in the Drosophila eye., PMID:17141162

Association study of putative promoter polymorphisms in the neuroplastin gene and schizophrenia., PMID:17123723

Anti-phencyclidine monoclonal antibody binding capacity is not the only determinant of effectiveness, disproving the concept that antibody capacity is easily surmounted., PMID:16507651

Effects of anti-phencyclidine and anti-(+)-methamphetamine monoclonal antibodies alone and in combination on the discrimination of phencyclidine and (+)-methamphetamine by pigeons., PMID:16479372

Development of immunopharmacotherapy against drugs of abuse., PMID:16472221

Increased phencyclidine-induced hyperactivity following cortical cholinergic denervation., PMID:16237333

Immunotherapy for the treatment of drug abuse., PMID:16023218

The medial septum mediates impairment of prepulse inhibition of acoustic startle induced by a hippocampal seizure or phencyclidine., PMID:15325789

Therapeutic vaccines for substance dependence., PMID:14761239

Therapeutic vaccines for substance dependence., PMID:12901575

Treatment of adverse effects of excessive phencyclidine exposure in rats with a minimal dose of monoclonal antibody., PMID:12829731

Synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP) is expressed differentially in phencyclidine-treated rats and is increased in the nucleus accumbens of patients with schizophrenia., PMID:12784099

Vaccines against drugs of abuse: a viable treatment option?, PMID:12558457

Phencyclidine - Effects on Human Performance and Behavior., PMID:26256594

A single dose of monoclonal anti-phencyclidine IgG offers long-term reductions in phencyclidine behavioral effects in rats., PMID:12065708

Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects., PMID:11840308

Detection of analytes by immunoassay using up-converting phosphor technology., PMID:11373074

Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane., PMID:10901699

Induction of cAMP response element modulator (CREM) and inducible cAMP early repressor (ICER) expression in rat brain by uncompetitive N-methyl-D-aspartate receptor antagonists., PMID:10871295

Anti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats., PMID:10688594

Screening postmortem blood and tissues for nine classes [correction of cases] of drugs of abuse using automated microplate immunoassay., PMID:10664895

MK-801-induced expression of Fos protein family members in the rat retrosplenial granular cortex., PMID:10462695

Pharmacokinetic mechanisms for obtaining high renal coelimination of phencyclidine and a monoclonal antiphencyclidine antigen-binding fragment of immunoglobulin G in the rat., PMID:9808688

Crystal structure of monoclonal 6B5 Fab complexed with phencyclidine., PMID:9786848

Pharmacodynamics of a monoclonal antiphencyclidine Fab with broad selectivity for phencyclidine-like drugs., PMID:9618414

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Phencyclidine/PCP Antibody (6B5) [RGN09801]
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