Catalog No.
PHE32601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SLC19A1 (Leu455-Gln591).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Intestinal folate carrier 1,FOLT,Solute carrier family 19 member 1,RFC1,hSLC19A1,IFC-1,SLC19A1,RFT-1,FLOT1,RFC,Placental folate transporter,Reduced folate transporter 1,Reduced folate transporter,Reduced folate carrier protein,hRFC
Purification
Purified by antigen affinity column.
Accession
P41440
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Molecular basis of SLC19A1-mediated folate and cyclic dinucleotide transport., PMID:40175380
Association of Vitamin B12 and Polymorphism of TCN2 with Early-Onset Post-Stroke Depression., PMID:39619496
Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform., PMID:38801272
A high-throughput single-cell RNA expression profiling method identifies human pericyte markers., PMID:37812061
Reduced folate carrier 1 is present in retinal microvessels and crucial for the inner blood retinal barrier integrity., PMID:37328777
Augustine Blood Group System and Equilibrative Nucleoside Transporter 1., PMID:35221865
Application of Various Statistical Models to Explore Gene-Gene Interactions in Folate, Xenobiotic, Toll-Like Receptor and STAT4 Pathways that Modulate Susceptibility to Systemic Lupus Erythematosus., PMID:26689915
NCCTG N0821 (Alliance): a phase II first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status., PMID:25157767
Epigenetic modulation of RFC1, MHC2TA and HLA-DR in systemic lupus erythematosus: association with serological markers and six functional polymorphisms of one-carbon metabolic pathway., PMID:24333266
Interleukin-6 regulates anti-arthritic effect of methotrexate via reduction of SLC19A1 expression in a mouse arthritis model., PMID:22546471
Subcellular localization and distribution of the reduced folate carrier in normal rat tissues., PMID:21556118
Expression of folate transporters in human placenta and implications for homocysteine metabolism., PMID:20036773
Phase II trial of pemetrexed plus bevacizumab for second-line therapy of patients with advanced non-small-cell lung cancer: NCCTG and SWOG study N0426., PMID:19841321
Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells., PMID:19692428
Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells., PMID:18316334
Importance of folate-homocysteine homeostasis during early embryonic development., PMID:18067451
Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells., PMID:12519783
Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis., PMID:12175915
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells., PMID:11509559
Localization of a human reduced folate carrier protein in the mitochondrial as well as the cell membrane of leukemia cells., PMID:11280750
Topological and functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion., PMID:10347183
Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier., PMID:9767079
Gene amplification and increased expression of the reduced folate carrier in transport elevated K562 cells., PMID:9605439
Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells., PMID:9426700
For research use only. Not for human or drug use.
