Catalog No.
YHB04901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser22-Ser120
Predicted molecular weight
22.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60931
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CTNS, Cystinosin
Note
For research use only.
The value of Korean, American, and Chinese ultrasound risk stratification systems combined with BRAF(V600E) mutation for detecting papillary thyroid carcinoma in cytologically indeterminate thyroid nodules., PMID:37940765
Omic Studies on In Vitro Cystinosis Model: siRNA-Mediated CTNS Gene Silencing in HK-2 Cells., PMID:37949358
Functional analysis of the CTNS gene exonic variants predicted to affect splicing., PMID:38009794
Single phage proteins sequester TIR- and cGAS-generated signaling molecules., PMID:38014003
Evaluation of the efficacy of cystinosin supplementation through CTNS mRNA delivery in experimental models for cystinosis., PMID:38016974
Cystinosis: Status of research and treatment in India and the world., PMID:38018544
CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy., PMID:38018843
Impact of compliance to oral cysteamine treatment on the costs of Kidney failure in patients with nephropathic cystinosis in the United Kingdom., PMID:38031005
Studies with Human-Induced Pluripotent Stem Cells Reveal That CTNS Mutations Can Alter Renal Proximal Tubule Differentiation., PMID:38069326
Event-related potential (ERP) evidence for visual processing differences in children and adults with cystinosis (CTNS gene mutations)., PMID:38087330
Neurologic involvement in cystinosis: Focus on brain lesions and new evidence of four-repeat (4R-) Tau immunoreactivity., PMID:38101161
Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides., PMID:38103556
Extrarenal complications of cystinosis., PMID:38127152
Cardiac troponins and coronary artery calcium score: a systematic review., PMID:38336618
Gene editing improves endoplasmic reticulum-mitochondrial contacts and unfolded protein response in Friedreich's ataxia iPSC-derived neurons., PMID:38420191
Lysosomal cystine accumulation activates mTOR signaling in cystinosis: are mTOR inhibitors the cure?, PMID:38519228
MFSD12 depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis., PMID:38545650
Residual Cystine Transport Activity for Specific Infantile and Juvenile CTNS Mutations in a PTEC-Based Addback Model., PMID:38607085
Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis., PMID:38633264
Cortical impairment and reduced muscle mass in children and young adults with nephropathic cystinosis., PMID:38864569
Associations Between Biomarkers of Myocardial Injury and Systemic Inflammation and Risk of Incident Ventricular Arrhythmia., PMID:38904572
Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread., PMID:38990725
Cystinosis-Associated Metabolic Bone Disease Across Ages and CKD Stages 1 to 5D/T., PMID:39049782
Long-term effects of luteolin in a mouse model of nephropathic cystinosis., PMID:39096619
Implications of Age for the Diagnostic and Prognostic Value of Cardiac Troponin T and I., PMID:39119905
Leptin signalling altered in infantile nephropathic cystinosis-related bone disorder., PMID:39210624
A systematic review and meta-analysis evaluating the association of high sensitivity troponin levels with outcomes in patients with stable coronary artery disease., PMID:39235073
Molecular characterization of clinically isolated Pseudomonas aeruginosa with varying resistance to ceftazidime-avibactam and ceftolozane-tazobactam collected as a part of the ATLAS global surveillance program from 2020 to 2021., PMID:39254297
Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy., PMID:39294696
Mitigative role of cysteamine against unilateral renal reperfusion injury in Wistar rats., PMID:39372204
Reconstitution of Rab11-FIP4 Expression Rescues Cellular Homeostasis in Cystinosis., PMID:39434668
Single phage proteins sequester signals from TIR and cGAS-like enzymes., PMID:39478223
The Value of Biomarkers in Major Cardiovascular Surgery Necessitating Cardiopulmonary Bypass., PMID:39484111
ZenoSWATH DIA proteomics and clustering analysis of the effect of cysteamine at the cellular level in cystinotic fibroblasts., PMID:39504626
Immunomodulatory effects of cysteamine and its potential use as a host-directed therapy for tuberculosis., PMID:39530101
Cystinosis metabolic bone disease: inflammatory profile in human peripheral blood mononuclear cells and derived osteoclasts., PMID:39540998
An Open-Label, Phase III Study to Assess the Efficacy and Safety of Cysteamine Ophthalmic Solution 0.55% in Japanese Cystinosis Patients., PMID:39618989
Lysosomal reduced thiols are essential for mouse embryonic development., PMID:39764028
Nexinhib20 inhibits JFC1-mediated mobilization of a subset of CD11b/CD18+ vesicles decreasing integrin avidity, but does not inhibit Rac1., PMID:39883854
Targeting oxidative stress-induced lipid peroxidation enhances podocyte function in cystinosis., PMID:39980044
Cystinosin is involved in Na+/H+ Exchanger 3 trafficking in the proximal tubular cells: new insights in the renal Fanconi syndrome in cystinosis., PMID:39990449
Novel mechanism for tubular injury in nephropathic cystinosis., PMID:40111391
Transplantation of Wild-Type Hematopoietic Stem and Progenitor Cells Improves Disease Phenotypes in a Mucopolysaccharidosis IIIC Mouse Model., PMID:40126917
Inhibition of Tyrosinase and Melanogenesis by Carboxylic Acids: Mechanistic Insights and Safety Evaluation., PMID:40286213
Long-term outcomes in nephropathic cystinosis: a review., PMID:40369127
Computational prediction of deleterious nonsynonymous SNPs in the CTNS gene: implications for cystinosis., PMID:40375073
Untangling Traffic Jams: RAB11FIP4 Orchestrates Cellular Recovery in Cystinosis., PMID:40395987
Emerging therapeutic strategies for cystinosis., PMID:40469087
Supplementing sialic acid analogs overcomes radiotherapy resistance in triple-negative breast cancer by exacerbating ER stress., PMID:40505348
For research use only. Not for human or drug use.
