Catalog No.
YHK95601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp133
Predicted molecular weight
17.82 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96LK0
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Centrosomal protein of 19 kDa, C3orf34, Cep19, CEP19
Note
For research use only.
Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice., PMID:24268657
RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly., PMID:28428259
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base., PMID:28625565
CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme., PMID:28659385
Gating Ciliary Transport., PMID:28697332
Homozygous mutation in CEP19, a gene mutated in morbid obesity, in Bardet-Biedl syndrome with predominant postaxial polydactyly., PMID:29127258
A distal centriolar protein network controls organelle maturation and asymmetry., PMID:30258116
RABL2 positively controls localization of GPCRs in mammalian primary cilia., PMID:30578315
Analysis of the "centrosome-ome" identifies MCPH1 deletion as a cause of centrosome amplification in human cancer., PMID:32681070
Comparative transcriptome provides insights into the selection adaptation between wild and farmed foxes., PMID:34646484
CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export., PMID:36074075
The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport., PMID:37606072
Severe Early-Onset Obesity and Diabetic Ketoacidosis due to a Novel Homozygous c.169C>T p.Arg57* Variant in CEP19 Gene., PMID:38585545
Architecture of RabL2-associated complexes at the ciliary base: A structural modeling perspective: Deciphering the structural organization of ciliary RabL2 complexes., PMID:38991980
For research use only. Not for human or drug use.
