Catalog No.
YHE93102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly1072-Leu1360
Predicted molecular weight
34.29 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52701
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNA mismatch repair protein Msh6, MutS protein homolog 6, MSH6, GTBP, hMSH6, GTMBP, G/T mismatch-binding protein, MutS-alpha 160 kDa subunit, p160
Note
For research use only.
Association between Deficient MSH2/MSH6 vs MLH1/PMS2 Status and Survival Rates in Localized Colorectal Cancer: A Nationwide Cohort Study., PMID:39807593
Pyrithione zinc alters mismatch repair to trigger tumor immunogenicity., PMID:39814851
Frequency and Impact of Constitutional Mismatch Repair Deficiency in Patients With High-Grade Glioma, a Retrospective Analysis of 7 Years in Pakistan: an IRRDC Study., PMID:39819126
Mutation Analysis of TMB-High Colorectal Cancer: Insights Into Molecular Pathways and Clinical Implications., PMID:39822019
Mixture effects of arsenic and chromium on erythrocytic nuclear abnormalities and expression of DNA repair, tumor suppressor and apoptotic genes in liver of zebrafish., PMID:39826661
Mismatch repair (MMR) and microsatellite instability (MSI) phenotypes across solid tumors: A comprehensive cBioPortal study on prevalence and prognostic impact., PMID:39827722
Familial analysis: pulmonary Birt-Hogg-Dubé syndrome in two siblings., PMID:39842902
Novel microsatellite instability test of sebaceous tumours to facilitate low-cost universal screening for Lynch syndrome., PMID:39847610
Lynch Syndrome-Impact of the Type of Deficient Mismatch Repair Gene Mutation on Diagnosis, Clinical Presentation, Surveillance and Therapeutic Approaches., PMID:39859102
[Application of PMS2 and MSH6 double-antibody detection in screening of mismatch repair deficient tumors]., PMID:39863527
Frequency and Molecular Characteristics of Mismatch Repair-deficient Status among Multiple Synchronous Colorectal Cancers., PMID:39882230
Lynch syndrome screening in colorectal and endometrial cancers in Iceland., PMID:39886913
MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma., PMID:39894875
Constitutional Mismatch Repair Deficiency: Scoping Review of a Cancer-Predisposition Syndrome With Distinctive Cutaneous Findings., PMID:39910726
Case report: Chemotherapy plus sintilimab for the treatment of gastroesophageal junction hepatoid adenocarcinoma with liver metastasis: a case study with literature review., PMID:39931054
Comparison of survival outcomes for patients with Lynch vs non-Lynch syndrome and microsatellite unstable colorectal cancer treated with immunotherapy., PMID:39932790
Obesity correlates to the microsatellite instability of endometrial cancer: A retrospective observational study., PMID:40009888
A case of multiple advanced colon cancers with spontaneous regression of only one lesion after biopsy: a case report and literature review., PMID:40029573
Are all mismatch repair deficient endometrial cancers created equal? A large, retrospective, tertiary center experience., PMID:40058269
Protein arginine methyltransferase 6 enhances immune checkpoint blockade efficacy via the STING pathway in MMR-proficient colorectal cancer., PMID:40086819
[Sessile serrated lesion with dysplasia and invasion]., PMID:40089942
MMR deficiency is frequent in colorectal carcinomas with diffuse SLFN11 immunostaining: clinicopathologic and molecular study of 31 cases identified among 3,300 tumors., PMID:40105034
Prevalence of Mismatch Repair Deficiency in Primary Prostate Cancer in a Large Prospective Cohort., PMID:40105779
Study on the Application of MLPA Detection for Large Fragment Loss of Mismatch Repair Genes in Chinese HNPCC Families., PMID:40116103
Microsatellite Stable Colorectal Tumours in Patients with Lynch Syndrome: A Case Report and Systematic Review Analysing Clinical Features and Implications for Immunotherapy., PMID:40133691
Serum-Based Proteomic Approach to Identify Clinical Biomarkers of Radiation Exposure., PMID:40149344
Coexisting germline variants of MLH1 and MSH6 in a patient with Lynch syndrome who had uterine and ovarian cancer., PMID:40160885
Causes of DNA mismatch repair deficiency in sebaceous skin lesions demonstrating loss of MLH1 protein expression: constitutional over somatic MLH1 promoter methylation., PMID:40208414
Germline variants in patients from the Iranian hereditary colorectal cancer registry., PMID:40223084
Impact of TP53 Alterations on Clinical Outcomes in Penile Squamous Cell Carcinoma., PMID:40240224
The Clinical Outcomes Among Patients Under 60 Years Old with Lynch Syndrome: Variations Based on Different Mutation Patterns., PMID:40244260
Family adenomatous polyposis come across dome type adenocarcinoma: a case report and literature review., PMID:40247408
Immunohistochemical characterization of differentiation-associated transcription factors, tumor suppressor genes, and mismatch repair genes in rabbit uterine adenocarcinoma., PMID:40257238
Microsatellite Status, Tumor Budding, CD3 and CD8 T Cell Densities in Relation to Invasiveness, Lymph Node Involvement in Colorectal Adenocarcinoma., PMID:40263681
Identification of genomic variants associated with colorectal cancer heredity in indigenous populations of the Amazon., PMID:40287430
The role of MLH1, MSH2 and MSH6 in the development of colorectal cancer in Uganda., PMID:40295928
Correlation between Isocitrate Dehydrogenase Mutation and Immunohistochemical Expression of DNA Mismatch Repair Proteins in the Prognosis of Gliomas., PMID:40302099
Molecular Subtype and Mutational Profile of Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia., PMID:40341112
[Preliminary analysis of mRNA m7G modifications in human Adenocarcinoma of esophagogastric junction]., PMID:40350398
Gastrointestinal Amphicrine Carcinoma: A Clinicopathologic Study of Five Patients., PMID:40350569
Pathogenic germline variants in mismatch repair genes in patients with microsatellite instability-high gastric cancer., PMID:40353075
Renal epithelioid aggressive angiomyolipoma in a patient with tuberous sclerosis and past contralateral benign renal angiomyolipoma., PMID:40377620
Detecting microsatellite instability in cancer via multiplexed orthogonal gap-enhanced Raman tags., PMID:40386153
Impact of germline variants on breast and ovarian cancer risk in Japanese women: an original cohort study and meta-analysis., PMID:40403695
Microsatellite instability and mismatch repair deficiency in bladder urothelial carcinoma: a Tunisian single-center study., PMID:40415014
Detection rates of multigene panel and exome testing in patients with previous negative BRCA1/2 results., PMID:40418377
Mismatch Repair Proteins Immunostaining in Lip Squamous Cell Carcinoma: A Role in Lip Carcinogenesis?, PMID:40439366
Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability., PMID:40469174
Evaluation of immunohistochemical expression of mismatch repair genes product in colorectal carcinoma and its correlation with clinicopathological parameters in a sample of Iraqi patients., PMID:40485379
Clinicopathological Characteristics of Upper Tract Urothelial Cancer With Loss of Immunohistochemical Expression of Mismatch Repair Proteins., PMID:40488817
For research use only. Not for human or drug use.
