Catalog No.
YHE22901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val37-Asn140
Predicted molecular weight
23.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P38570
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mucosal lymphocyte 1 antigen, Integrin alpha-E, Integrin alpha-IEL, HML-1 antigen, CD103, ITGAE
Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade. PMID: 33827905
CD8+CD103+ tissue-resident memory T cells convey reduced protective immunity in cutaneous squamous cell carcinoma. PMID: 33479027
SMAD4 TGF-β-independent function preconditions naive CD8+ T cells to prevent severe chronic intestinal inflammation. PMID: 35426367
Effect of variation in ITGAE on risk of sarcoidosis, CD103 expression, and chest radiography. PMID: 19604725
Role of ITGAE in the development of autoimmune diabetes in non-obese diabetic mice. PMID: 25525188
Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells. PMID: 33584680
The SKI proto-oncogene restrains the resident CD103+CD8+ T cell response in viral clearance. PMID: 32612153
T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development. PMID: 32268106
Human Vδ2 T cells are a major source of interleukin-9. PMID: 27791087
CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features. PMID: 30381402
Smad and NFAT pathways cooperate to induce CD103 expression in human CD8 T lymphocytes. PMID: 24477908
Dynamic Imaging of IEL-IEC Co-Cultures Allows for Quantification of CD103-Dependent T Cell Migration. PMID: 34067987
CD4+ T cell help guides formation of CD103+ lung-resident memory CD8+ T cells during influenza viral infection. PMID: 25308332
Cloning and expression of P67 protein of Mycoplasma leachii. PMID: 29062201
Enhanced hydrolysis of lignocellulosic biomass with doping of a highly thermostable recombinant laccase. PMID: 31260768
Production of an Antibody Fragment (scFv) Targeting PcrV Protein of Pseudomonas aeruginosa in Fed-Batch Cultivation Mode. PMID: 34641643
bTRM Control of Murine Cytomegalovirus CNS Reactivation., PMID:40508083
A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease., PMID:40502135
5-ALA Assisted Surgery of Human Glioblastoma Samples Reveals an Enrichment of T Cells Expressing PD-1 and CD103 in the Intermediate and Marginal Layers., PMID:40498413
Origin of Hypofunctional CD103+ NK Cells in Cirrhosis-Associated Ascites., PMID:40498379
Impact of irae characteristics on efficacy of consolidative immunotherapy following chemoradiotherapy in locally advanced NSCLC., PMID:40483449
Assessment of compartment-specific CD103-positive cells for prognosis prediction of colorectal cancer., PMID:40481870
The phenotypic and functional characteristics of intrahepatic CD69+CD103+ tissue-resident MAIT cells in primary biliary cholangitis., PMID:40460780
Harnessing local and system immune profiling delineating differential responders to first-line sintilimab (anti-PD-1 antibody) combined with chemotherapy in extensive-stage small cell lung cancer: an exploratory biomarker analysis of a phase II study., PMID:40404633
Enhancing mesothelin CAR T cell therapy for pancreatic cancer with an oncolytic herpes virus boosting CAR target antigen expression., PMID:40366419
Conversion Surgery Performed Following Durvalumab Combined With Gemcitabine and Cisplatin in Cholangiocarcinoma: A Case Report., PMID:40294984
Sex-Specific Anti-Inflammatory Effects of a Ketogenic Diet in a Mouse Model of Allergic Airway Inflammation., PMID:40243683
Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in mice., PMID:40240341
Cytotoxic T Lymphocyte Density and PD-L1 Expression Predict the Response to Anti-PD1 Therapy in Recurrent Oral Squamous Cell Carcinoma., PMID:40221937
IRF4-regulated transcriptional and functional heterogeneity of lung-resident CD11b+ cDC2 subsets during influenza virus infection., PMID:40209091
Investigating the therapeutic potential of tryptophan and vitamin A in modulating immune responses in celiac disease: an experimental study., PMID:40178602
Regulation of respiratory CD8+ T-cell immunity by suppressive monocyte-like dendritic cells (MCs)., PMID:40163680
Bacterial vaginosis associates with dysfunctional T cells and altered soluble immune factors in the cervicovaginal tract., PMID:40131862
A backbone-based flow cytometry approach to decipher regulatory T cell trajectories in the human thymus., PMID:40098950
CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment., PMID:40084939
Innate immune system signaling and intestinal dendritic cells migration to the brain underlie behavioral changes after microbial colonization in adult mice., PMID:40068794
Irreversible electroporation combined with PD-L1/IL-6 dual blockade promotes anti-tumor immunity via cDC2/CD4+T cell axis in MHC-I deficient pancreatic cancer., PMID:40068706
Effector CD8 T cell differentiation in primary and breakthrough SARS-CoV-2 infection in mice., PMID:40057586
A Comprehensive Analysis of FGF/FGFR Signaling Alteration in NSCLC: Implications in Prognosis and Microenvironment., PMID:40001320
Triggering mouth-resident antiviral CD8+ T cells potentiates experimental periodontitis., PMID:39988203
CD103+ dendritic cell-fibroblast crosstalk via TLR9, TDO2, and AHR signaling drives lung fibrogenesis., PMID:39964756
The fungal protein Lingzhi-8 ameliorates psoriasis-like dermatitis in mice through gut CD103+ tolerogenic dendritic cells, retinaldehyde dehydrogenase 2, and Dectin-1., PMID:39954596
TLR5 Signaling Causes Dendritic Cell Dysfunction and Orchestrates Failure of Immune Checkpoint Therapy against Ovarian Cancer., PMID:39932226
Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT., PMID:39896683
MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination., PMID:39877094
OMIP-110: A 37-Color Spectral Flow Cytometric Panel to Assess Transcription Factors and Chemokine Receptors in Human Intestinal Lymphoid Cells., PMID:39838760
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression., PMID:39838375
Novel biomarkers: the RUNX family as prognostic predictors in colorectal cancer., PMID:39822248
ECM29/proteasome-mediated self-antigen generation by CNS-resident neuroglia promotes regulatory T cell activation., PMID:39786996
Intratumoral Injection of Engineered Mycobacterium smegmatis Induces Antitumor Immunity and Inhibits Tumor Growth., PMID:39780958
Characterization of Dendritic Cells and Myeloid-Derived Suppressor Cells Expressing Major Histocompatibility Complex Class II in Secondary Lymphoid Organs in Systemic Lupus Erythematosus-Prone Mice., PMID:39769367
BACH2-driven tissue resident memory programs promote HIV-1 persistence., PMID:39763845
Newly Found Rat CD103 - Dendritic Cells Represent a Highly Immunogenic Subpopulation of Type-2 Conventional Dendritic Cells, Corresponding to Known Dendritic Cell Subsets in Mice and Humans., PMID:39754477
Immunohistochemical evaluation of LGR5, CD71, CD138 and CXCR3 markers in the small bowel mucosa of participants with celiac disease and persons with normal bowel mucosa., PMID:39747719
Diabetes impairs IFNγ-dependent antibacterial defense in the lungs., PMID:39746547
Polyphenol oxidase cross-linking enhances whey protein-induced systemic food allergy by regulating miRNA in CD4+ T cells., PMID:39744957
Live Akkermansia muciniphila boosts dendritic cell retinoic acid synthesis to modulate IL-22 activity and mitigate colitis in mice., PMID:39734222
CCR2 restricts IFN-γ production by hippocampal CD8 TRM cells that impair learning and memory during recovery from WNV encephalitis., PMID:39725999
Interferon Epsilon Loss Is Elusive 9p21 Link to Immune-Cold Tumors, Resistant to Immune Checkpoint Therapy, and Endogenous CXCL9/10 Induction., PMID:39725169
Novel approach to alleviate lupus nephritis: targeting the NLRP3 inflammasome in CD8+CD69+CD103+ TRM cells., PMID:39716284
CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer., PMID:39696312
Local cell therapy using CCL19-expressing allogeneic mesenchymal stem cells exerts robust antitumor effects by accumulating CD103+ IL-12-producing dendritic cells and priming CD8+ T cells without involving draining lymph nodes., PMID:39672553
G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo., PMID:39650661
Differential predictive value of resident memory CD8+T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy., PMID:39631852
Arabinogalactan from Cynanchum atratum induces tolerogenic dendritic cells in gut to restrain autoimmune response and alleviate collagen-induced arthritis in mice., PMID:39586124
Immune microenvironment of Epstein-Barr virus (EBV)-negative compared to EBV-associated gastric cancers: implications for immunotherapy., PMID:39572160
For research use only. Not for human or drug use.
