Catalog No.
YHE50402
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Gly215
Predicted molecular weight
36.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P46976
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GN-1, GN1, GYG, Glycogenin-1, GYG1
The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex. PMID: 35793618
Update on new muscle glycogenosis. PMID: 28737584
GYG1 causing progressive limb girdle myopathy with onset during teenage years (polyglucosan body myopathy 2). PMID: 29422440
Clinical heterogeneity and phenotype/genotype findings in 5 families with GYG1 deficiency. PMID: 29264399
Functional characterization of GYG1 variants in two patients with myopathy and glycogenin-1 deficiency. PMID: 31791869
Cardiomyopathy as presenting sign of glycogenin-1 deficiency-report of three cases and review of the literature. PMID: 27718144
Muscle glycogen synthesis and breakdown are both impaired in glycogenin-1 deficiency. PMID: 29142088
Polyglucosan myopathy and functional characterization of a novel GYG1 mutation. PMID: 29143313
Late-onset polyglucosan body myopathy in five patients with a homozygous mutation in GYG1. PMID: 26652229
Sequential spontaneous compartment syndrome in multiple limbs in a young adult with GYG1 gene mutation. PMID: 33257366
Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage. PMID: 31628455
Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans. PMID: 29321365
Start codon mutation of GYG1 causing late-onset polyglucosan body myopathy with nemaline rods. PMID: 27544502
An HNF4α-microRNA-194/192 signaling axis maintains hepatic cell function. PMID: 28465351
Lysosomal glycogen accumulation in Pompe disease results in disturbed cytoplasmic glycogen metabolism. PMID: 36111639
Tissue Proteome Signatures Associated with Five Grades of Prostate Cancer and Benign Prostatic Hyperplasia. PMID: 31576646
A new muscle glycogen storage disease associated with glycogenin-1 deficiency. PMID: 25272951
Glycogen Synthesis in Glycogenin 1-Deficient Patients: A Role for Glycogenin 2 in Muscle. PMID: 28453664
Distribution of Exonic Variants in Glycogen Synthesis and Catabolism Genes in Late Onset Pompe Disease (LOPD). PMID: 37185710
Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study. PMID: 29637127
Analysis of rare coding variants in 200,000 exome-sequenced subjects reveals novel genetic risk factors for type 2 diabetes. PMID: 34216101
Glycogenin-1 deficiency and inactivated priming of glycogen synthesis. PMID: 20357282
Muscle pathology and whole-body MRI in a polyglucosan myopathy associated with a novel glycogenin-1 mutation. PMID: 26255073
Glycogenin-2 is dispensable for liver glycogen synthesis and glucagon-stimulated glucose release. PMID: 25751106
Exogenous fibroblast growth factor-10 induces cystic lung development with altered target gene expression in the presence of heparin in cultures of embryonic rat lung. PMID: 22261751
Effect of Ganoderma lucidum spores intervention on glucose and lipid metabolism gene expression profiles in type 2 diabetic rats. PMID: 25994182
For research use only. Not for human or drug use.
