Bioinformatics analysis of potential common pathogenic mechanism for carotid atherosclerosis and Parkinson's disease., PMID:37649719
Hippocampal Inflammation and Gene Expression Changes in Peripheral Lipopolysaccharide Challenged Mice Showing Sickness and Anxiety-Like Behaviors., PMID:37661396
CD14 and CSF1R as developmental molecular targets for the induction of osteoarthritis., PMID:37693684
Gender-specific lncRNA-miRNA-mRNA regulatory network to reveal potential genes for primary open-angle glaucoma., PMID:37774963
Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 on metabolic unhealthy obese patients., PMID:37877121
Comprehensive analyses for the coagulation and macrophage-related genes to reveal their joint roles in the prognosis and immunotherapy of lung adenocarcinoma patients., PMID:38022584
Identification of Candidate Genes Associated With Development of Vascular Cognitive Impairment by Integrated Bioinformatics Analysis Combined With Biological Experiments., PMID:38055620
Bioinformatics analysis of hub genes as osteoarthritis prognostic biomarkers., PMID:38129488
Integration of bioinformatics analysis to identify possible hub genes and important pathways associated with clear cell renal cell carcinoma., PMID:38159064
Proteomic profiling of aqueous humor-derived exosomes in Vogt-Koyanagi-Harada disease and Behcet's uveitis., PMID:38185270
Reanalysis and validation of the transcriptional pleural fluid signature in pleural tuberculosis., PMID:38288122
Identification of inflammatory biomarkers in IgA nephropathy using the NanoString technology: a validation study in Caucasians., PMID:38291238
Identification of the C1qDC gene family in grass carp (Ctenopharyngodon idellus) and the response of C1qA, C1qB, and C1qC to GCRV infection in vivo and in vitro., PMID:38447782
In a novel autoimmune and high-pressure glaucoma model a complex immune response is induced., PMID:38515755
Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer's disease., PMID:38521860
Unveiling biomarkers and therapeutic targets in IgA nephropathy through large-scale blood transcriptome analysis., PMID:38552291
NLRC4-mediated pyroptosis was involved in coagulation disorders of acute pancreatitis., PMID:38571451
RNA sequencing of the thalamus and rostral ventral medulla in rats with chronic orofacial pain., PMID:38630191
Complement C1q is involved in the activation of membrane attack complexes, regulation of bacterial infectious inflammation, and apoptosis through overexpression in primary cells of silver pomfret (Pampus argenteus) in vitro., PMID:38670188
Tissue-resident C1q + macrophages exert anti-aging potential through the Sirt1 pathway., PMID:38724770
Exploring the molecular mechanism of sepsis-associated encephalopathy by integrated analysis of multiple datasets., PMID:38781871
Cholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma., PMID:38890370
Mass Spectrometry Proteomics Characterization of Plasma Biomarkers for Colorectal Cancer Associated With Inflammation., PMID:38911905
Deciphering the molecular nexus between Omicron infection and acute kidney injury: a bioinformatics approach., PMID:39027131
Causal relationship between complement C1QB and colorectal cancer: a drug target Mendelian randomization study., PMID:39109334
Bioinformatics screening and verification of ischemic stroke-related key genes and drug prediction., PMID:39140683
Non-alcoholic fatty liver disease and heart failure: A comprehensive bioinformatics and Mendelian randomization analysis., PMID:39143741
Association of M2 macrophages with EMT in glioma identified through combination of multi-omics and machine learning., PMID:39145022
Identification of crosstalk genes and immune characteristics between Alzheimer's disease and atherosclerosis., PMID:39188714
Effect of Kruppel-like factor 4 on PTZ-induced acute seizure mice., PMID:39234952
Double-negative T cells with a distinct transcriptomic profile are abundant in the peripheral blood of patients with breast cancer., PMID:39254769
Identifying High Recurrence Risk in Breast Carcinoma Patients Through Spatial Transcriptomic Analysis., PMID:39348993
Protein biomarkers in assessing kidney quality before transplantation‑current status and future perspectives (Review)., PMID:39370783
First-Trimester Preeclampsia-Induced Disturbance in Maternal Blood Serum Proteome: A Pilot Study., PMID:39408980
Serum proteomic changes related to residual impairment in remittent depression are associated with immune and inflammatory processes., PMID:39424870
Absolute Quantitative Targeted Monitoring of Potential Plasma Protein Biomarkers: A Pilot Study on Healthy Individuals., PMID:39457715
Biomarkers associated with papillary thyroid carcinoma and Hashimoto's thyroiditis: Bioinformatic analysis and experimental validation., PMID:39510033
Clinical Significance of Complement and Coagulation Cascades Genes for Patients With Acute Lymphoblastic Leukemia., PMID:39523585
Localization of brain neuronal IL-1R1 reveals specific neural circuitries responsive to immune signaling., PMID:39563437
Divergent changes in complement pathway gene expression in schizophrenia and bipolar disorder: Links to inflammation and neurogenesis in the subependymal zone., PMID:39616737
Identification of key genes associated with endometriosis and endometrial cancer by bioinformatics analysis., PMID:39650066
Epigenetic regulation of complement C1Q gene expression., PMID:39697348
Proteomic Analysis of 442 Clinical Plasma Samples From Individuals With Symptom Records Revealed Subtypes of Convalescent Patients Who Had COVID-19., PMID:40207927
Microarray analysis of the effects of Acthar Gel versus methylprednisolone in a model of focal segmental glomerulosclerosis in female rats., PMID:40223398
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Rare C1q deficiency presenting as pediatric SLE: A case study of two consanguineous siblings., PMID:40316395
Transcriptomic analysis of differential expression between surviving and nonsurviving patients infected by the SARS-CoV-2 Delta variant., PMID:40374692
Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038
Identification of a Novel Homozygous C1QB Mutation in an Iranian Girl: Expanding the Clinical Spectrum of C1q Deficiency., PMID:40506420
Synaptic pruning genes networks in Alzheimer's disease: correlations with neuropathology and cognitive decline., PMID:40515808
The production and secretion of complement component C1q by human mast cells. PMID: 27648858
Neuroinflammation in the pathogenesis of axonal Charcot-Marie-Tooth disease caused by lack of GDAP1. PMID: 31271761
Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems. PMID: 35163105
Identification of dysregulated pathways underlying HTLV-1-associated myelopathy/tropical spastic paraparesis through co-expression network analysis. PMID: 33405203
Identification of novel gene and pathway targets for human epilepsy treatment. PMID: 26742644
Red-Fleshed Apples Rich in Anthocyanins and White-Fleshed Apples Modulate the Aorta and Heart Proteome in Hypercholesterolaemic Rats: The AppleCOR Study. PMID: 35268023
Association of brain immune genes with social behavior of inbred mouse strains. PMID: 25895500
Histopathological comparison of the onset of peri-implantitis and periodontitis in rats. PMID: 26804139
Bioinformatics Analysis of Potential Candidates for Therapy of TDRD7 Deficiency-Induced Congenital Cataract. PMID: 25997407
Extracellular vesicle proteomics and phosphoproteomics identify pathways for increased risk in patients hospitalized with COVID-19 and type 2 diabetes mellitus. PMID: 36736734
Biosynthetic homeostasis and resilience of the complement system in health and infectious disease. PMID: 31262714
Reduced expression of innate immunity-related genes in lymph node metastases of luminal breast cancer patients. PMID: 33658651
Identification of the Hub Genes Related to Nerve Injury-Induced Neuropathic Pain. PMID: 32508579
Increased complement C1q level marks active disease in human tuberculosis. PMID: 24647646
C1q regulatory region polymorphism down-regulating murine c1q protein levels with linkage to lupus nephritis. PMID: 12133956
Identification of key genes and miRNAs related to polycystic ovary syndrome by comprehensive analysis of microarray. PMID: 36544152
Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification. PMID: 33763081
Identifying putative candidate genes and pathways involved in immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) infection. PMID: 22486506
Trajectory of change in brain complement factors from neonatal to young adult humans. PMID: 33190236
[Biomarkers screening for viral myocarditis through proteomics analysis of plasma exosomes]. PMID: 30772974
Gene expression profile changes in rat dorsal horn after sciatic nerve injury. PMID: 28033741
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease. PMID: 26950848
Transcriptome analysis of human dorsal striatum implicates attenuated canonical WNT signaling in neuroinflammation and in age-related impairment of striatal neurogenesis and synaptic plasticity. PMID: 34275915
Identification of an Alveolar Macrophage-Related Core Gene Set in Acute Respiratory Distress Syndrome. PMID: 34103966
DNA methylation-based diagnostic and prognostic biomarkers of nasopharyngeal carcinoma patients. PMID: 32541515
Genetic Profiles Related to Pathogenesis in Sporadic Intracranial Aneurysm Patients. PMID: 31238169
Identification of Molecular Correlations Between DHRS4 and Progressive Neurodegeneration in Amyotrophic Lateral Sclerosis By Gene Co-Expression Network Analysis. PMID: 35479082
Data-independent acquisition of the proteomics of spleens from chickens infected by avian leukosis virus. PMID: 31475084
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. PMID: 19029902
Bioinformatics analysis of gene expression profiles of Inclusion body myositis. PMID: 32259312
Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS. PMID: 35842220
Subunits of C1Q Are Associated With the Progression of Intermittent Claudication to Chronic Limb-Threatening Ischemia. PMID: 35433866
Whole Exome Sequencing in Early-onset Systemic Lupus Erythematosus. PMID: 30008451
Insomnia and depressive behavior of MyD88-deficient mice: Relationships with altered microglial functions. PMID: 34971898
Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma. PMID: 36471393
Exploring the pathogenesis of diabetic kidney disease by microarray data analysis. PMID: 36059966
Bovine neonate is deficient in innate immunity at birth. PMID: 33640760
Microarray-based analysis of renal complement components reveals a therapeutic target for lupus nephritis. PMID: 34433493
Identification of Genes with Altered Methylation in Osteoclast Differentiation and Its Roles in Osteoporosis. PMID: 35699379
Complement factors in adult peripheral nerve: a potential role in energy metabolism. PMID: 15145549
Proteomics Analysis of Plasma-Derived Exosomes Unveils the Aberrant Complement and Coagulation Cascades in Dermatomyositis/Polymyositis. PMID: 36507906
[Screening and preliminary validation of biomarkers in sputum-negative pulmonary tuberculosis based on positron emission tomography/computed tomography and transcriptomics]. PMID: 35658381
Transforming growth factor-beta1 induces transforming growth factor-beta1 and transforming growth factor-beta receptor messenger RNAs and reduces complement C1qB messenger RNA in rat brain microglia. PMID: 11074155
Comprehensive Genetic Analysis of Tuberculosis and Identification of Candidate Biomarkers. PMID: 35345666
Identification of key pathways and core genes involved in atherosclerotic plaque progression. PMID: 33708894
Transcriptomic Analysis Reveals Genetic Cross-Talk between Periodontitis and Hypothyroidism. PMID: 35450027
GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL. PMID: 36703279
Delayed inflammatory mRNA and protein expression after spinal cord injury. PMID: 21975064
Functional recombinant human complement C1q with different affinity tags. PMID: 33621564
Molecular mechanisms for synchronized transcription of three complement C1q subunit genes in dendritic cells and macrophages. PMID: 21862594
Complement C1q expression in Erythema nodosum leprosum. PMID: 29499046
Dysfunctional Network and Mutation Genes of Hypertrophic Cardiomyopathy. PMID: 35126952
Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxins in vivo and in vitro. PMID: 7870303
Alteration of Serum Proteome in Levo-Thyroxine-Euthyroid Thyroidectomized Patients. PMID: 35330001
[Bioinformatics analysis identifies aging/senescence-induced genes in calcified plaques]. PMID: 36594382
Anti-C1q autoantibodies specific against the globular domain of the C1qB-chain from patient with lupus nephritis inhibit C1q binding to IgG and CRP. PMID: 22209113
Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections. PMID: 25454803
Induction of the complement component C1qB in brain of transgenic mice with neuronal overexpression of human cyclooxygenase-2. PMID: 11810182
In silico and in vitro studies on the protein-protein interactions between Brugia malayi immunomodulatory protein calreticulin and human C1q. PMID: 25184227
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma. PMID: 33707956
Variation in complement protein C1q is not a major contributor to cognitive impairment in Parkinson's disease. PMID: 25817358
Complement component C1q is produced by isolated articular chondrocytes. PMID: 31634584
Transcriptome profiling of whole blood cells identifies PLEK2 and C1QB in human melanoma. PMID: 21698244
Detection of molecular signatures and pathways shared by Alzheimer's disease and type 2 diabetes. PMID: 34813915
The identification of a novel splicing mutation in C1qB in a Japanese family with C1q deficiency: a case report. PMID: 24160257
Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis. PMID: 36307392
Characterization of C1q in teleosts: insight into the molecular and functional evolution of C1q family and classical pathway. PMID: 20615881
Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity. PMID: 36523269
Expression of complement C1qB and C4 mRNAs during rat brain development. PMID: 7955342
C1qB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis. PMID: 10471215
Prognostic Implications of the Complement Protein C1q in Gliomas. PMID: 31649675
Dysfunctional network of hub genes in hypertrophic cardiomyopathy patients. PMID: 36628247
Novel protein biomarkers associated with coronary artery disease in statin-treated patients with familial hypercholesterolemia. PMID: 28434814
Heat Shock Protein Upregulation Supplemental to Complex mRNA Alterations in Autoimmune Glaucoma. PMID: 36291747
Complement C1qB and C4 mRNAs responses to lesioning in rat brain. PMID: 1426121
[Research advances in the Cap gene of circovirus and its encoding capsid protein]. PMID: 23895015
Identification of TYROBP and C1QB as Two Novel Key Genes With Prognostic Value in Gastric Cancer by Network Analysis. PMID: 33014868
IRF4-activated TEX41 promotes the malignant behaviors of melanoma cells by targeting miR-103a-3p/C1QB axis. PMID: 34915882
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. PMID: 36517889
Development and Validation of a Prognostic Gene Signature Correlated With M2 Macrophage Infiltration in Esophageal Squamous Cell Carcinoma. PMID: 34926275
Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease. PMID: 36180898
Identification of Key Biomarkers and Pathways for Maintaining Cognitively Normal Brain Aging Based on Integrated Bioinformatics Analysis. PMID: 35356296
Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology. PMID: 34932275
Integrative analysis of DNA methylation and gene expression profiles to identify biomarkers of glioblastoma. PMID: 34773808
Genetic screening of early-onset patients with systemic lupus erythematosus by a targeted next-generation sequencing gene panel. PMID: 35086391
Jun, Gal, Cd74, and C1qb as potential indicator for neuropathic pain. PMID: 29331040
Association of C1QB gene polymorphism with schizophrenia in Armenian population. PMID: 21951915
C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment. PMID: 36443341
Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis. PMID: 34124269
Prognostic and immune-related value of complement C1Q (C1QA, C1QB, and C1QC) in skin cutaneous melanoma. PMID: 36110204
Identification of Key Diagnostic Markers and Immune Infiltration in Osteoarthritis. PMID: 35473522
M2 macrophage-related gene signature in chronic rhinosinusitis with nasal polyps. PMID: 36466903
Detection of Complement C1q B Chain Overexpression and Its Latent Molecular Mechanisms in Cervical Cancer Tissues Using Multiple Methods. PMID: 36313902
Identification of Molecular Signatures and Candidate Drugs in Vascular Dementia by Bioinformatics Analyses. PMID: 35221911
TREM2 triggers microglial density and age-related neuronal loss. PMID: 30548312
A Novel Diagnostic Predictive Model for Idiopathic Short Stature in Children. PMID: 34603204
Screening of the Key Genes and Signalling Pathways for Diabetic Nephropathy Using Bioinformatics Analysis. PMID: 35923621
Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19. PMID: 33138195
Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease. PMID: 36229464
Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu Decoction against ischemic stroke. PMID: 35525530
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages. PMID: 33782087
Complement C1q (C1qA, C1qB, and C1qC) May Be a Potential Prognostic Factor and an Index of Tumor Microenvironment Remodeling in Osteosarcoma. PMID: 34079754
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis. PMID: 35604302
Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis. PMID: 34122426
For research use only. Not for human or drug use.
