Catalog No.
YHK87401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln46-Leu166
Predicted molecular weight
16.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8TD06
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AGR3, AG3, PDIA18, Protein disulfide isomerase family A, member 18, Breast cancer membrane protein 11, AG-3, Anterior gradient protein 3, hAG-3, BCMP11, Anterior gradient 3 homolog
AGR3 promotes the stemness of colorectal cancer via modulating Wnt/β-catenin signalling. PMID: 31526829
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD. PMID: 34177583
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner. PMID: 32724387
AGR2 and AGR3 play an important role in the clinical characterization and prognosis of basal like breast cancer. PMID: 34462207
Extracellular AGR3 regulates breast cancer cells migration via Src signaling. PMID: 31611954
Estrogen-regulated AGR3 activates the estrogen receptor signaling pathway to promote tamoxifen resistance in breast cancer. PMID: 34519905
AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection. PMID: 25875093
Profile of anterior gradient 3 (AGR3) mRNA expression and serum levels in benign and malignant breast tumors. PMID: 34057117
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer. PMID: 35857928
Combination of TP53 and AGR3 to distinguish ovarian high-grade serous carcinoma from low-grade serous carcinoma. PMID: 29620196
Anterior Gradient 3 Promotes Breast Cancer Development and Chemotherapy Response. PMID: 31291711
The Endoplasmic Reticulum Resident Protein AGR3. Required for Regulation of Ciliary Beat Frequency in the Airway. PMID: 25751668
Single-cell proteomics reveals changes in expression during hair-cell development. PMID: 31682227
The NS5A protein of hepatitis C virus transcriptionally upregulates the AGR3 gene expression. PMID: 25868611
The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer. PMID: 21451362
Anterior Gradient-3: a novel biomarker for ovarian cancer that mediates cisplatin resistance in xenograft models. PMID: 22361111
Differential expression of anterior gradient protein 3 in intrahepatic cholangiocarcinoma and hepatocellular carcinoma. PMID: 24747240
Over-expression of Anterior Gradient 3 Is Associated With Tumor Progression and Poor Survival in Gastric Cancer. PMID: 36593009
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease. PMID: 16222343
The Anterior GRadient (AGR) family proteins in epithelial ovarian cancer. PMID: 34452625
Crystal structure of human anterior gradient protein 3. PMID: 29969106
Autoinducing peptide-based quorum signaling systems in Clostridioides difficile. PMID: 34773906
Anterior gradient protein 3 is associated with less aggressive tumors and better outcome of breast cancer patients. PMID: 26170690
Anterior Gradient Protein 3 and S100 Calcium-Binding Protein P Levels in Different Endometrial Epithelial Compartments May Play an Important Role in Recurrent Pregnancy Failure. PMID: 33917163
Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer. PMID: 29262583
Anterior gradient proteins in gastrointestinal cancers: from cell biology to pathophysiology. PMID: 36068336
Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development. PMID: 22945652
Lack of association between physical activity in smokers and plasma glutathione peroxidase levels. PMID: 18398046
Molecular epidemiology of physical activity and cancer. PMID: 15668499
Carcinogen-DNA adducts as a biomarker for cancer risk. PMID: 16824556
Better cancer biomarker discovery through better study design. PMID: 22998109
The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio. PMID: 25630240
Neighborhood Physical Disorder in New York City. PMID: 27482283
Identification of androgen-regulated genes in human prostate. PMID: 22735730
Candidate Genes of Allergic Dermatitis Are Associated with Immune Response. PMID: 35028126
Methicillin-Resistant Staphylococcus aureus ST80 Induce Lower Cytokine Production by Monocytes as Compared to Other Sequence Types. PMID: 30687287
Global distribution and evolution of Panton-Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus, 1981-2007. PMID: 20367458
Design options for molecular epidemiology research within cohort studies. PMID: 16103435
Vaginal Tampon Colonization by Staphylococcus aureus in Healthy Women. PMID: 32680868
GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. PMID: 31959922
Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells. PMID: 23294566
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. PMID: 29739929
Whole genome microarray analysis in non-small cell lung cancer. PMID: 26019623
Gene expression and metabolic response of bovine oviduct epithelial cells to the early embryo. PMID: 31022701
Integrated Bioinformatics Analysis for the Screening of Hub Genes and Therapeutic Drugs in Androgen Receptor-Positive TNBC. PMID: 36157217
Radiogenomic Analysis of Breast Cancer by Using B-Mode and Vascular US and RNA Sequencing. PMID: 32013793
Using GPS Data to Study Neighborhood Walkability and Physical Activity. PMID: 26558700
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers. PMID: 33176066
Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients. PMID: 31646105
Body mass index across the life course: emergence of race-by-sex disparities in early childhood. PMID: 30961991
Analyses of Employer Medical Claims Data to Assess Receipt of High-Priority Preventive Health Services. PMID: 32173164
What does the talking?: quorum sensing signalling genes discovered in a bacteriophage genome. PMID: 24475037
Agr2-interacting Prod1-like protein Tfp4 from Xenopus laevis is necessary for early forebrain and eye development as well as for the tadpole appendage regeneration. PMID: 30912273
Agr genes, missing in amniotes, are involved in the body appendages regeneration in frog tadpoles. PMID: 23412115
Addressing patient's unmet social needs: disparities in access to social services in the United States from 1990 to 2014, a national times series study. PMID: 35305617
Differential Gene Expression in Ductal Carcinoma In Situ of the Breast Based on ERBB2 Status. PMID: 28178722
Using Google Street View to audit neighborhood environments. PMID: 21146773
Immobilizing 1-3 nm Ag nanoparticles in reduced graphene oxide aerogel as a high-effective catalyst for reduction of nitroaromatic compounds. PMID: 31672347
Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. PMID: 12967497
Community-associated Staphylococcus aureus pneumonia among Greek children: epidemiology, molecular characteristics, treatment, and outcome. PMID: 27140201
Prediction of breast cancer proteins involved in immunotherapy, metastasis, and RNA-binding using molecular descriptors and artificial neural networks. PMID: 32444848
Glucagon secretion in relation to insulin sensitivity in healthy subjects. PMID: 16362283
Prenatal exposure to airborne polycyclic aromatic hydrocarbons and childhood growth trajectories from age 5-14 years. PMID: 31352299
The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration. PMID: 34676214
The role of calmodulin in the gravitropic response of the Arabidopsis thaliana agr-3 mutant. PMID: 8771800
Weight-related behaviors when children are in school versus on summer breaks: does income matter? PMID: 26032276
Associations between body mass index and park proximity, size, cleanliness, and recreational facilities. PMID: 23448416
Community-associated methicillin-resistant and methicillin-sensitive Staphylococcus aureus: skin and soft tissue infections in Hong Kong. PMID: 18272316
Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2. PMID: 24710632
The association between benzo[a]pyrene-DNA adducts and body mass index, calorie intake and physical activity. PMID: 17536763
Genetic analysis of high-level mupirocin resistance in the ST80 clone of community-associated meticillin-resistant Staphylococcus aureus. PMID: 19833783
Neighborhood food environment and walkability predict obesity in New York City. PMID: 19337520
Physical activity and asthma symptoms among New York City Head Start Children. PMID: 19863284
15-Deoxy-Δ(12,14)-prostaglandin J(2) induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines. PMID: 23403520
Body composition, abdominal fat distribution, and prostate-specific antigen test results. PMID: 19124516
Patterns of Physical Activity Among Older Adults in New York City: A Latent Class Approach. PMID: 26091927
Quantitative analysis of biofilm formation of methicillin-resistant Staphylococcus aureus (MRSA) strains from patients with orthopaedic device-related infections. PMID: 21595755
Obesity and future prostate cancer risk among men after an initial benign biopsy of the prostate. PMID: 23613026
Individual- and school-level sociodemographic predictors of obesity among New York City public school children. PMID: 23132672
Three-year survey of community-acquired methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a French university hospital. PMID: 16026895
Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. PMID: 12228818
Development of a Neighborhood Walkability Index for Studying Neighborhood Physical Activity Contexts in Communities across the U.S. over the Past Three Decades. PMID: 31214976
The phenotypes and genotypes associated with biofilm formation among methicillin-susceptible Staphylococcus aureus (MSSA) isolates collected from a tertiary hospital in Terengganu, Malaysia. PMID: 36805382
Disparities in trajectories of changes in the unhealthy food environment in New York City: A latent class growth analysis, 1990-2010. PMID: 31247345
Genome Analysis of Clostridium difficile PCR Ribotype 014 Lineage in Australian Pigs and Humans Reveals a Diverse Genetic Repertoire and Signatures of Long-Range Interspecies Transmission. PMID: 28123380
Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family. PMID: 15935701
[High prevalence of community- and hospital-acquired infections of methicillin-resistant Staphylococcus aureus containing Panton-Valentine leukocidin gene in Algiers]. PMID: 19875247
The urban built environment and obesity in New York City: a multilevel analysis. PMID: 17465178
For research use only. Not for human or drug use.
