Catalog No.
PHD44101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD247/CD3Z (Arg52-Arg164).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
CD3Z, CD247, TCRZ, T-cell receptor T3 zeta chain, T3Z, T-cell surface glycoprotein CD3 zeta chain
Purification
Purified by antigen affinity column.
Accession
P20963
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Profiling lymphocyte subpopulations in peripheral blood under efalizumab treatment of psoriasis by multi epitope ligand cartography (MELC) robot microscopy., PMID:17229602
Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2., PMID:18089830
Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with oesophageal squamous cell carcinoma., PMID:20029417
Using gene co-expression network analysis to predict biomarkers for chronic lymphocytic leukemia., PMID:21044363
Association of CD247 with systemic lupus erythematosus in Asian populations., PMID:22004975
IRF5 polymorphism predicts prognosis in patients with systemic sclerosis., PMID:22440820
Down regulation of T cell receptor expression in COPD pulmonary CD8 cells., PMID:23977094
Expression pattern of T-helper 17 cell signaling pathway and mucosal inflammation in celiac disease., PMID:24325470
Effect of induction therapy on the expression of molecular markers associated with rejection and tolerance., PMID:26286066
TCR-CD3ζ gene polymorphisms and expression profile in rheumatoid arthritis., PMID:27118209
Clinical Significance of Circulating CD33+CD11b+HLA-DR- Myeloid Cells in Patients with Stage IV Melanoma Treated with Ipilimumab., PMID:27178742
Effects of immuno-related gene polymorphisms on a bispecific antibody targeting colorectal cancer cell., PMID:29790821
The Role of CD247 Polymorphisms in Bulgarian Patients with Systemic Lupus Erythematosus., PMID:30064597
CAR T-cell therapy for multiple myeloma: state of the art and prospects., PMID:34048683
Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3+ NK Cell Subset with a Bcl11b-Regulated T Cell Signature., PMID:34625521
Advances in the study of CD47-based bispecific antibody in cancer immunotherapy., PMID:35575882
Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis., PMID:37868834
Identification of a Fully Human Antibody VH Domain Targeting Anaplastic Lymphoma Kinase (ALK) with Applications in ALK-Positive Solid Tumor Immunotherapy., PMID:38804307
Nonsense CD247 mutations show dominant-negative features in T-cell receptor expression and function., PMID:38992472
Effects of immunorelated gene polymorphisms on trastuzumab targeting breast cancer cell in vitro., PMID:39392082
Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures., PMID:39462122
For research use only. Not for human or drug use.
