Catalog No.
PHE03401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD80 (Val35-Asn242).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CD80,BB1,T-lymphocyte activation antigen CD80,CD28LG,B7,CD28LG1,LAB7,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1
Purification
Purified by antigen affinity column.
Accession
P33681
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
STAT3 inhibition in combination with CD47 blockade inhibits osteosarcoma lung metastasis., PMID:40529368
CTLA-4 blockade in ovarian cancer immunotherapy: Mechanisms and clinical strategies., PMID:40482550
NEK2 regulates B cell function and the severity of experimental autoimmune encephalomyelitis., PMID:40481479
Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming., PMID:40437667
CD80 Antibody and MTX Co-Engineered Extracellular Vesicles Targets CD80+ Macrophages to Suppress Inflammation and Alleviate Chronic Inflammatory Diseases., PMID:40416732
pH-responsive nano-vaccine combined with anti-PD-1 antibodies for enhanced immunotherapy of breast cancer., PMID:40365283
Blocking plasma cell fate enhances antigen-specific presentation by B cells to boost anti-tumor immunity., PMID:40360528
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice., PMID:40320111
A promising endeavor against human cytomegalovirus: Predominant epitopes-based recombinant subunit vaccine RHEcIE1/pp65/pp150., PMID:40277436
Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis., PMID:40270956
Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity., PMID:40168991
High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype., PMID:40158231
A novel trivalent inactivated Salmonella vaccine formulated with CpG ODNs to enhance the cellular immunity in chickens., PMID:40120243
Mannose-modified erythrocyte membrane-coated Chuanmingshen violaceum polysaccharide PLGA nanoparticles to improve immune responses in mice., PMID:40080925
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors., PMID:40074330
[Early conversion to belatacept post-transplantation: state of the art and expert opinion]., PMID:40066607
Comprehensive immunophenotyping reveals distinct tumor microenvironment alterations in anti-PD-1 sensitive and resistant syngeneic mouse model., PMID:40064915
Humanized FcεRI Expressed on Mouse Eosinophils Mediates IgE-Facilitated Eosinophil Antigen Presentation., PMID:39996772
Modified CD40L-Activated B-Cell Proliferation Model for Validating the Suppressive Activity of CD40-CD154 Pathway Inhibitors., PMID:39994946
Anti-Inflammatory Effects of Ex Vivo-Generated Donor Antigen-Specific Immunomodulatory Cells on Pancreatic Islet Transplantation., PMID:39981681
Optimizing rWTC-MBTA Vaccine Formulations, Dosing Regimens, and Cryopreservation Techniques to Enhance Anti-Metastatic Immunotherapy., PMID:39941108
Recombinant CD80 fusion protein combined with discoidin domain receptor 1 inhibitor for cancer treatment., PMID:39918582
Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity., PMID:39911575
PD-L1-CD80 interactions are required for intracellular signaling necessary for dendritic cell migration., PMID:39879305
MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination., PMID:39877094
Langerhans Cells Drive Tfh and B Cell Responses Independent of Canonical Cytokine Signals., PMID:39868337
Plasma membrane-coated nanoparticles and membrane vesicles to orchestrate multimodal antitumor immunity., PMID:39864848
Lipid-Rapamycin Nanovaccines Overcome the Antidrug Antibody Barrier in Biologic Therapies., PMID:39847793
Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy., PMID:39847577
Antagonism of CD28 blocks allergic responses in the ovalbumin-induced asthmatic model mice., PMID:39842142
Discovery of a common light chain bispecific antibody targeting PD-1 and PD-L1 by Hybridoma-to-Phage-to-Yeast (H2PtY) platform., PMID:39839911
Novel Sarcoidosis Epitope Augments MHCII, CD80/CD86 Expression, Promotes B-Cell Differentiation and IgG Production., PMID:39836049
An OMV-Based Nanovaccine as Antigen Presentation Signal Enhancer for Cancer Immunotherapy., PMID:39811977
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity., PMID:39806486
Anti-CD4 monoclonal antibody prevents chronic graft-versus-host disease in mice by inducing immune tolerance of CD8+ T cells and alleviating thymus injury., PMID:39776911
Characterization of Dendritic Cells and Myeloid-Derived Suppressor Cells Expressing Major Histocompatibility Complex Class II in Secondary Lymphoid Organs in Systemic Lupus Erythematosus-Prone Mice., PMID:39769367
Deficiencies of Inducible Costimulator (ICOS) During Chronic Infection with Toxoplasma gondii Upregulate the CD28-Dependent Cytotoxicity of CD8+ T Cells and Their Effector Function Against Tissue Cysts of the Parasite., PMID:39682747
K. pneumoniae ghosts serve as a novel vaccine formulation to enhance immune responses of A. baumannii subunit vaccine in mice., PMID:39674425
Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ regulatory T cells., PMID:39667222
Prevalence of hybrid TLR4+M2 monocytes/macrophages in peripheral blood and lung of systemic sclerosis patients with interstitial lung disease., PMID:39635531
The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice., PMID:39596396
The clinical significance of signal regulatory protein alpha expression in the immune environment of gastric cancer., PMID:39589589
Dendritic cell maturation is induced by p53-armed oncolytic adenovirus via tumor-derived exosomes enhancing systemic antitumor immunity., PMID:39499326
Tumor Antigen-Tethered Spiked Virus-Like- Poly(Lactic-Co-Glycolic Acid)-Nanoparticle Vaccine Enhances Antitumor Ability Through Th9 Promotion in Mice., PMID:39493273
A protocol to isolate and characterize pure monocytes and generate monocyte-derived dendritic cells through FBS-Coated flasks., PMID:39397067
Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity., PMID:39383033
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Autoreactive B cells remain active despite clinical disease control in rheumatoid arthritis., PMID:39342827
Generation of Devil Facial Tumour Cells Co-Expressing MHC With CD80, CD86 or 41BBL to Enhance Tumour Immunogenicity., PMID:39313933
A squalene oil emulsified MPL-A and anti-CD200/CD300a antibodies adjuvanted whole-killed Leishmania vaccine provides durable immunity against L. donovani parasites., PMID:39288578
For research use only. Not for human or drug use.
