Catalog No.
EHD72202
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ile192
Predicted molecular weight
22.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26842
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Immunoinflammatory evidence of rheumatoid arthritis caused by COVID-19., PMID:40495223
Monitoring anti-Rituximab antibodies in myasthenia gravis affects the time to event during Rituximab treatment., PMID:40488894
A multi-omics resource of B cell activation reveals genetic mechanisms for immune-mediated diseases., PMID:40475139
CD70 CAR-T cells empowered by TS-2021 through ex vivo transduction show potent antitumor efficacy against glioblastoma., PMID:40474210
Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805
Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study., PMID:40442445
Rapamycin-modified CD169low/-tolDC promotes skin graft survival in mice via IL-10+Breg., PMID:40414462
Phenotypic Profile of Waldenström Macroglobulinaemia B-Cells: Establishment of a Diagnosis Scoring System and Clinico-Biological Correlations., PMID:40407640
Prognostic value of the expression of CD27 and CD117 in newly diagnosed multiple myeloma patients., PMID:40389820
Altered CD27-related T cell subsets reflect immune imbalance in systemic lupus erythematosus., PMID:40381105
Assessment of expression of TNF signaling proteins in Dengue cases as potential biomarkers for predicting severity of the disease in the study population., PMID:40373942
GATA1-mediated Notch signaling augment antitumor immunity of CD11b+CD27- natural killer cells maturation via BCL9/β-catenin signal., PMID:40366806
Novel Tear Biomarkers in Ocular Graft Versus Host Disease Associated with Th1/Th2 Immune Responses: A Case Series and Literature Review., PMID:40362547
Genetic liability to critically ill COVID-19 increased risk of HER2-positive breast cancer through the immune pathway: A Mendelian randomization study., PMID:40355230
Amlexanox inhibits production of type I interferon and suppresses B cell differentiation in vitro: a possible therapeutic option for systemic lupus erythematosus and other systemic inflammatory diseases., PMID:40341181
CD27 costimulation supports metabolic fitness of CD4+ T cells by enhancing de novo nucleotide and protein synthesis., PMID:40324771
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics., PMID:40322080
Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965
Progressive accumulation of circulating CD27-CD28- effector/memory CD8+ T cells in patients with lung cancer blunts responses to immune checkpoint inhibitor therapy., PMID:40307573
CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study., PMID:40306966
Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial., PMID:40298406
Comprehensive pan-cancer analysis identifies PLAG1 as a key regulator of tumor immune microenvironment and prognostic biomarker., PMID:40276502
The role of double-negative B cells in the pathogenesis of systemic lupus erythematosus., PMID:40274006
Integrated Analysis of PSMB8 Expression and Its Potential Roles in Hepatocellular Carcinoma., PMID:40261568
Pathogenomic fingerprinting to identify associations between tumor morphology and epigenetic states., PMID:40239399
CD70 recruitment to the immunological synapse is dependent on CD20 in B cells., PMID:40232798
Multiparametric Profiling of Circulating Immune Cells Identifies an Expansion of CD25high Switched Memory B Cells in Osteoarthritis., PMID:40229860
Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection., PMID:40222009
Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia., PMID:40207214
Expression of costimulatory molecule CD70 is prognostic in small cell lung cancer., PMID:40205178
CD40L stimulates tumor-infiltrating B-cells and improves ex vivo TIL expansion., PMID:40199608
Neutrophils negatively control IL-17A-producing γδ T cell frequencies in a contact-dependent manner under physiological conditions., PMID:40181985
Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic., PMID:40173043
Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection., PMID:40173042
Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia., PMID:40149717
Soluble CD27 differentially predicts resistance to anti-PD1 alone but not with anti-CTLA-4 in melanoma., PMID:40148586
Aberrant Lower CD6 Expression on Peripheral B Cells Associated With Liver/Kidney Injury and Autoantibody Production of Systemic Lupus Erythematosus Patients., PMID:40134233
Genetic and Epigenetic Changes in Melanoma Progression: A TCGA-based Study., PMID:40127249
Comprehensive pan-cancer analysis reveals CD70 as a promising therapeutic target and biomarker in clear cell renal cell carcinoma., PMID:40113005
Diagnostic values of CD27, CD20 and MPO in pediatric ulcerative colitis., PMID:40089083
Proteomic signatures of type 2 diabetes predict the incidence of coronary heart disease., PMID:40087642
Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease., PMID:40078987
IL-4 alters TLR7-induced B cell developmental program in lupus., PMID:40068727
Causal relationship between Baff-R expression and normal pressure hydrocephalus: insights from Mendelian randomization analysis., PMID:40055671
The Role of IL-10-Producing Regulatory B Cells in Children With Primary Nephrotic Syndrome., PMID:40052241
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes., PMID:40049222
CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity., PMID:40046047
Exploring the dual role of SIVA1 in cancer biology., PMID:40024298
Molecular insights into ulcerative colitis and orbital inflammation., PMID:40021664
Development and Preclinical Evaluation of [64Cu]Cu-NOTA-ABDB6: A CD70 and Albumin Dual-Binding Tracer with Improved Pharmacokinetics., PMID:40015924
For research use only. Not for human or drug use.
