InVivoMAb Anti-HSV1/HHV1 gD/Envelope glycoprotein D (Fd138-80)

Catalog No.

VVV21402

Species reactivity

Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1)

Host species

Human

Isotype

IgG1

Clonality

Monoclonal

Target

Envelope glycoprotein D, gD, gD, US6

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q05059

Applications

Blocking, ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Fd138-80

Anti-herpes simplex virus type 1 activity of the Rohdea chinensis (Baker) N. Tanaka aqueous extracts., PMID:40412773

Chemical Synthesis Creates Single Glycoforms of the Ectodomain of Herpes Simplex Virus-1 Glycoprotein D., PMID:38117537

Selection, activity, and nuclease stabilization of cross-neutralizing DNA aptamers targeting HSV-1 and HSV-2., PMID:37925791

A self-binding immune complex vaccine elicits strong neutralizing responses against herpes simplex virus in mice., PMID:37205110

Interleukin-6 and indoleamine-2,3-dioxygenase as potential adjuvant targets for Papillomavirus-related tumors immunotherapy., PMID:36405719

Restoring Herpesvirus Entry Mediator (HVEM) Immune Function in HVEM-/- Mice Rescues Herpes Simplex Virus 1 Latency and Reactivation Independently of Binding to Glycoprotein D., PMID:32522859

Inhibition of herpes simplex virus by myricetin through targeting viral gD protein and cellular EGFR/PI3K/Akt pathway., PMID:32165083

Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model., PMID:30806747

Evaluation of the antiviral potential of the soluble forms of glycoprotein D receptors on ocular herpes caused by HSV-1 and HSV-2 infections in a transgenic mouse model., PMID:30575982

Dual Ligand Insertion in gB and gD of Oncolytic Herpes Simplex Viruses for Retargeting to a Producer Vero Cell Line and to Cancer Cells., PMID:29263257

US6 Gene Deletion in Herpes Simplex Virus Type 2 Enhances Dendritic Cell Function and T Cell Activation., PMID:29176979

Liposome-Mediated Herpes Simplex Virus Uptake Is Glycoprotein-D Receptor-Independent but Requires Heparan Sulfate., PMID:27446014

Activation of monocytic cells by immunostimulatory lipids conjugated to peptide antigens., PMID:22710358

Purified herpes simplex type 1 glycoprotein D (gD) genetically fused with the type 16 human papillomavirus E7 oncoprotein enhances antigen-specific CD8+ T cell responses and confers protective antitumor immunity., PMID:21985578

Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor., PMID:21382632

Bispecific adapter-mediated retargeting of a receptor-restricted HSV-1 vector to CEA-bearing tumor cells., PMID:20924362

Immune responses and therapeutic antitumor effects of an experimental DNA vaccine encoding human papillomavirus type 16 oncoproteins genetically fused to herpesvirus glycoprotein D., PMID:20739505

Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs., PMID:20525279

Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation., PMID:20519652

Immunization with HSV-1 glycoprotein C prevents immune evasion from complement and enhances the efficacy of an HSV-1 glycoprotein D subunit vaccine., PMID:19761834

Immunization with a dominant-negative recombinant HSV type 1 protects against HSV-1 skin disease in guinea pigs., PMID:18496565

Neurovirulent factor ICP34.5 uniquely expressed in the herpes simplex virus type 1 Delta gamma 1 34.5 mutant 1716., PMID:18300073

An HSV-1 gD mutant virus as an entry-impaired live virus vaccine., PMID:18243431

Nectin-1 expression by squamous cell carcinoma is a predictor of herpes oncolytic sensitivity., PMID:17164781

Cytoplasmic residues of herpes simplex virus glycoprotein gE required for secondary envelopment and binding of tegument proteins VP22 and UL11 to gE and gD., PMID:17035313

The first immunoglobulin-like domain of porcine nectin-1 is sufficient to confer resistance to pseudorabies virus infection in transgenic mice., PMID:16583156

Influence of sequential oligopeptide carriers on the bioactive structure of conjugated epitopes: comparative study of the conformation of a Herpes simplex virus glycoprotein gD-1 epitope in the free and conjugated form, and protein "built-in" crystal structure., PMID:16493659

A role for heparan sulfate 3-O-sulfotransferase isoform 2 in herpes simplex virus type 1 entry and spread., PMID:16336986

Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus., PMID:15110526

Enhanced resistance to herpes simplex virus type 1 infection in transgenic mice expressing a soluble form of herpesvirus entry mediator., PMID:15016549

In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa., PMID:14963155

Isolation of the enhanced neurovirulent HSV-1 strains from Korean patients., PMID:12803462

Axonal transport and sorting of herpes simplex virus components in a mature mouse visual system., PMID:12743269

Herpes simplex virus with highly reduced gD levels can efficiently enter and spread between human keratinocytes., PMID:11581399

Efficacy of polyclonal antibodies for treatment of ocular herpes simplex infection., PMID:11413405

Pseudotyping of glycoprotein D-deficient herpes simplex virus type 1 with vesicular stomatitis virus glycoprotein G enables mutant virus attachment and entry., PMID:10666285

Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential., PMID:9774565

Herpes simplex virus type 1 glycoproteins gB, gC and gD are major targets for CD4 T-lymphocyte cytotoxicity in HLA-DR expressing human epidermal keratinocytes., PMID:9472620

Effect of IL-4 and IL-12 liposomal formulations on the induction of immune response to bovine herpesvirus type-1 glycoprotein D., PMID:9364679

Analysis of herpes simplex virus type 1 glycoprotein D nucleotide sequence in human herpes simplex encephalitis., PMID:8799220

Neuroinvasive properties of herpes simplex virus type 1 glycoprotein variants are controlled by the immune response., PMID:8598469

N-linked oligosaccharides on herpes simplex virus glycoprotein gD are not essential for establishment of viral latency or reactivation in the mouse eye model., PMID:8030209

Soluble glycoprotein D blocks herpes simplex virus type 1 infection of rat eyes., PMID:1380093

Detection of the latency-associated transcript in neuronal cultures during the latent infection with herpes simplex virus type 1., PMID:1647075

Native herpes simplex virus glycoprotein D vaccine: immunogenicity and protection in animal models., PMID:1645898

Transplantation of syngeneic transfected cells to probe the in vivo immune response to viral proteins., PMID:1846831

Native HSV glycoprotein D subunit vaccine: analysis of in vitro T-cell activation and antigen presentation., PMID:1667262

Analysis of the role of antibody-dependent cellular cytotoxic antibody activity in murine neonatal herpes simplex virus infection with antibodies to synthetic peptides of glycoprotein D and monoclonal antibodies to glycoprotein B., PMID:2164044

Antibody to cloned HSV glycoproteins B and D plus adult human leukocytes protect neonatal mice from lethal HSV infection., PMID:2854958

Production, binding characteristics, and immunogenicity of heterologous anti-idiotypic antibody to herpes simplex virus glycoprotein C., PMID:3509672

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