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Anti-MAP4 Polyclonal Antibody

Catalog #:   PHD75401 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P27816
Overview

Catalog No.

PHD75401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MAP4 (Lys906-Glu1089).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MAP4,MAP-4,Microtubule-associated protein 4

Purification

Purified by antigen affinity column.

Accession

P27816

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MAP4 antibody (PHD75401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 22 kDa
    Observed MW: 22 kDa
References

Immune-modulatory effects of Spindlin-1 inhibitors., PMID:40512144

An Auxin Inducible Degradation System to Study Mklp2 Functions in MDCK Epithelial Cells., PMID:40490973

A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies., PMID:40473739

Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region., PMID:40455293

Hippocampal subfields: volume, neuropathological vulnerability and cognitive decline in Alzheimer's and Parkinson's disease., PMID:40448161

Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species., PMID:40448101

Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life., PMID:40442822

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference., PMID:40437880

Immunotherapy against tau fragment diminishes AD pathology, improving synaptic function and cognition., PMID:40426267

[Prospects for treating Alzheimer's disease]., PMID:40420451

Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization., PMID:40415369

Intracerebroventricular phospho-tau immunotherapy alleviates cortical phospho-tau burden and motor phenotype in a neuron-specific P301S tauopathy mouse., PMID:40403829

The role of autophagy in ischemic brain injury., PMID:40395988

Anti-cis P-tau attenuates tauopathy and enhances cognitive function following global cerebral ischemia in mice., PMID:40378437

Development of Zn-Based Tower-like Photoelectrochemical Sensor Array for Sandwich-Type Immunosensing Analysis of Tau., PMID:40374565

Dynamics of IgM and IgA Antibody Response Profile Against Vibrio cholerae Toxins A, B, and P., PMID:40331989

Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementias., PMID:40318118

A Novel Phosphorylated Tau Conformer Implicated in the Tauopathy Pathogenesis of Human Neurons., PMID:40305319

Facile generation of drug-like conformational antibodies specific for amyloid fibrils., PMID:40301692

Yellow fever virus infection alters mitochondrial network dynamics and trigger IFN-I response via TLR2 pathway., PMID:40300356

Nanobody-based double antibody sandwich colloidal gold test strips for rapid detection of urinary biomarkers NMP22 and survivin in bladder cancer., PMID:40300312

Daily high doses of atorvastatin alter neuronal morphology in a juvenile songbird model., PMID:40294005

KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway., PMID:40253697

Divergent disruptive effects of soluble recombinant tau assemblies on synaptic plasticity in vivo., PMID:40251677

Small-Molecule Mitotic Inhibitors as Anticancer Agents: Discovery, Classification, Mechanisms of Action, and Clinical Trials., PMID:40244152

Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1., PMID:40225568

Inhibition of tau neuronal internalization using anti-tau single domain antibodies., PMID:40175345

Enhancing anti-CD3 mAb-mediated diabetes remission in autoimmune diabetes through regulation of dynamin-related protein 1(Drp1)-mediated mitochondrial dynamics in exhausted CD8+T-cell subpopulations., PMID:40165248

Targeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques., PMID:40145301

Competitive electrochemical immunosensor for trace phosphorylated Tau181 analysis in plasma: Toward point-of-care technologies of Alzheimer's disease., PMID:40139011

Investigation of the HLA locus in autopsy-confirmed progressive supranuclear palsy., PMID:40132252

Influence of apolipoprotein E genotype on the proteomic profile in cerebral microdialysis after human severe traumatic brain injury: a prospective observational study., PMID:40109561

Clinical significance of "S" isoform of DCLK1 in different gastric cancer subtypes using newly produced monoclonal antibody., PMID:40109216

Association of dietary fatty acids with longitudinal change in plasma-based biomarkers of Alzheimer's disease., PMID:40107919

Shear stress preconditioning enhances periodontal ligament stem cell survival., PMID:40086040

DCLK1 in gastrointestinal cancer: A driver of tumor progression and a promising therapeutic target., PMID:40056091

Overlapping presence of β-amyloid, tau, p-tau, and α-synuclein in skin nerve fibers in Alzheimer's disease., PMID:40042672

Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis., PMID:40010959

18F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy., PMID:39994806

Eligibility for donanemab trial in a population-based study of cognitive aging., PMID:39966022

Associations of Cerebrospinal Fluid Orexin-A, Alzheimer Disease Biomarkers, and Cognitive Performance., PMID:39957622

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity., PMID:39956805

Biofluid biomarker changes following treatment with sabirnetug (ACU193) in INTERCEPT-AD, a phase 1 trial in early Alzheimer's disease., PMID:39955261

Multimer Detection System: A Universal Assay System for Differentiating Protein Oligomers from Monomers., PMID:39940966

Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's disease., PMID:39930142

The impact of apolipoprotein E, type ∊4 allele on Alzheimer's disease pathological biomarkers: a comprehensive post-mortem pilot-analysis., PMID:39913635

Clinical trials targeting tau should be halted., PMID:39908690

The value of CSF diagnostic and prognostic biomarkers in NMOSD and MOGAD in real-life use., PMID:39893752

Biomarker treatment effects in two phase 3 trials of gantenerumab., PMID:39887500

Modeling Sporadic Progressive Supranuclear Palsy in 3D Midbrain Organoids: Recapitulating Disease Features for In Vitro Diagnosis and Drug Discovery., PMID:39876539

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-MAP4 Polyclonal Antibody [PHD75401]
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