Catalog No.
RGK81601
Expression system
Mammalian Cells
Species reactivity
General
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
α-galactosyl epitope, αGal1-3βGal1-4GlcNAc, α-gal, alpha-gal epitope, α-D-Gal-(1→3)-β-D-Gal-(1→4)-D-GlcNAc, α-gal trisaccharide, gal-α-1,3-gal-β-1,4-GlcNAc, alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosamine, α-D-galactosyl-1,3-β-D-galactosyl-1,4-N-acetyl-D-glucosamine, α-D-galactopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-D-glucopyranose
Concentration
0.21 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
ChEBI: 18217
Applications
ELISA, SPR
Form
Liquid
Storage buffer
100 mM Pro-Ac, 20 mM Arg, pH 5.0
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
HKB7
Allergic reactions associated with tsetse fly bites., PMID:40485140
Enzyme replacement therapy using a modified α-N-acetylgalactosaminidase to suppress progressive glycolipid accumulation and escape from antidrug antibody formation in young human NAGA-transgenic/Gla-knockout mice., PMID:40446427
IgG to Galactose-Alpha-1,3-Galactose: Impact of Alpha-Gal IgE Sensitization, Blood Type, and Tick Bites., PMID:40407695
Alpha-gal allergy in a South Asian country., PMID:40369411
Connecting Diagnostics and Clinical Relevance of the α-Gal Syndrome-Individual Sensitization Patterns of Patients with Suspected α-Gal-Associated Allergy., PMID:40362849
Big Data-Driven Evolution of a Diagnostic Multiplex IgE-Test: Enhancing Accuracy and Efficacy in Allergy Diagnostics., PMID:40362486
Impact of Staphylococcus aureus colonization and skin abscesses on formation of human anti-αGal antibodies., PMID:40358758
Is Zebrafish a Good Model for the Alpha-Gal Syndrome?, PMID:40317760
Alpha-gal syndrome: Recognizing and managing a tick-bite-related meat allergy., PMID:40312115
Food allergy endotypes revisited., PMID:40306493
Pre-clinical strategies and emerging technologies driving advances in the alpha-gal syndrome., PMID:40180833
Mutations Inactivating Biosynthesis of Dispensable Carbohydrate-Antigens Prevented Extinctions in Primate/Human Lineage Evolution., PMID:40159432
Onset of Alpha-Gal Syndrome after Tick Bite, Washington, USA., PMID:40133079
Alpha-Gal Sensitization Dynamics in Individuals After Tick Bites With or Without Erythema Migrans., PMID:40108824
Detection of Anti-Non-α-Gal Xenoreactive Antibodies in Human Blood Products., PMID:40106379
Perioperative Outcomes After Bioprosthetic Valve Replacement in Patients Sensitized to Alpha-Gal., PMID:40098868
Tick salivary proteins metalloprotease and allergen-like p23 are associated with response to glycan α-Gal and mycobacterium infection., PMID:40087469
Lectin-Based Substrate Detection in Fabry Disease Using the Gb3-Binding Lectins StxB and LecA., PMID:40076891
French Guiana and AGS: a path to uncovering hidden clues., PMID:40056092
Conformational Profile of Galactose-α-1,3-Galactose (α-Gal) and Structural Basis of Its Immunological Response., PMID:40035364
Isotype diversity of antibodies specific for component allergens in the context of allergic diseases: eosinophilic esophagitis (EoE), asthma, and the alpha-gal syndrome (AGS)., PMID:39968192
Genetic and Immunological Insights into Tick-Bite Hypersensitivity and Alpha-Gal Syndrome: A Case Study Approach., PMID:39859393
Lentivirus-mediated gene therapy for Fabry disease: 5-year End-of-Study results from the Canadian FACTs trial., PMID:39794302
Insight into distribution and composition of nonhuman N-Glycans in mammalian organs via MALDI-TOF and MALDI-MSI., PMID:39778995
Multiple Allergen Simultaneous Test for Food Allergens Cannot Screen Wheat-Dependent, Exercise-Induced Anaphylaxis and α-Gal Syndrome., PMID:39742886
Editorial: Animal models of allergic diseases: from basic to preclinical research., PMID:39737061
A real-world pharmacovigilance analysis for agalsidase beta: findings from the FDA adverse event reporting database., PMID:39707961
Alpha-Gal Syndrome: A Review for the General Internist., PMID:39615839
Sensitization to α-gal and omega-5-gliadin in patients with chronic urticaria: clinical implications and need for targeted testing., PMID:39606606
Characterization of antibodies induced by immunization of mice with isoglobotrihexosylceramide (iGb3)., PMID:39552707
Longitudinal Follow-up Reveals Peripheral Immunological Changes Upon Tick Bite in a-Gal-Sensitized Individuals., PMID:39535897
Understanding American tegumentary leishmaniasis in urban Montes Claros, Brazil: insights from clinical, immunological and therapeutic investigations., PMID:39523648
Self-Tumor Antigens in Solid Tumors Turned into Vaccines by α-gal Micelle Immunotherapy., PMID:39458595
Increasing prevalence of galactose-α-1,3-galactose sensitization in the Danish general adult population., PMID:39441524
Recurrent tick bites induce high IgG1 antibody responses to α-Gal in sensitized and non-sensitized forestry employees in Luxembourg., PMID:39397273
Mysterious Allergy Caused by Tick Bite: Alpha-Gal Syndrome., PMID:39373596
Expression and predictive value of serum core fucosylated low molecular weight kininogen and alpha-galactosylated antibodies in patients with hepatic fibrosis., PMID:39311786
[TWO CASES OF α-GAL SYNDROME CAUSED BY INGESTION OF WILD BOAR MEAT]., PMID:39261044
Unraveling Alpha-Gal Syndrome: A Case Study of a Rare Meat Allergy., PMID:39184719
Immunotherapy with biodegradable nanoparticles encapsulating the oligosaccharide galactose-alpha-1,3-galactose enhance immune tolerance against alpha-gal sensitization in a murine model of alpha-gal syndrome., PMID:39183976
Alpha-Gal Syndrome and Cardiac Surgery., PMID:39097488
Tick salivary proteome and lipidome with low glycan content correlate with allergic type reactions in the zebrafish model., PMID:39074655
Clinical Presentation and Outcomes of Alpha-Gal Syndrome., PMID:39067555
Identification of Alpha-Gal glycolipids in saliva of Lone-Star Tick (Amblyomma americanum)., PMID:39053323
Allergenic potency of various foods of mammalian origin in patients with α-Gal syndrome., PMID:39007417
Mammalian Meat Allergy and IgE to Alpha-Gal in Central Virginia: Findings From a COVID-19 Vaccine and Patient Cohort., PMID:38944197
Anaphylaxis triggered by alpha-gal allergy., PMID:38934309
Thyroglobulin specific IgE and a possible link to suspected penicillin induced allergic skin manifestations - cross sectional study., PMID:38851521
Zebrafish gut microbiota composition in response to tick saliva biomolecules correlates with allergic reactions to mammalian meat consumption., PMID:38820703
The α-Gal KO Mouse Animal Model is a Reliable and Predictive Tool for the Immune-Mediated Calcification Assessment of Heart Valve Bioprostheses., PMID:38812319
For research use only. Not for human or drug use.
