Catalog No.
PHD72201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD27 (Thr21-Ile192).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CD27L receptor,TNFRSF7,T14,CD27 antigen,Tumor necrosis factor receptor superfamily member 7,CD27,T-cell activation antigen CD27
Purification
Purified by antigen affinity column.
Accession
P26842
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Monitoring anti-Rituximab antibodies in myasthenia gravis affects the time to event during Rituximab treatment., PMID:40488894
Adaptive immune changes in colorectal cancer: a focus on T and B cell activation genes., PMID:40484866
Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805
Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294
Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study., PMID:40442445
Interferon signatures fuel B cell hyperactivity and plasmablast expansion in systemic lupus erythematosus., PMID:40424895
The CD70-CD27 axis in cancer immunotherapy: Predictive biomarker and therapeutic target., PMID:40388162
Microbead-based synthetic niches for in vitro expansion and differentiation of human naïve B-cells., PMID:40385534
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics., PMID:40322080
Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity., PMID:40321757
Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965
CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study., PMID:40306966
Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial., PMID:40298406
The role of double-negative B cells in the pathogenesis of systemic lupus erythematosus., PMID:40274006
Desensitization With Proteasome Inhibition and Costimulation Blockade Modulates the Xenoreactive Humoral Response in Nonhuman Primate Xenotransplantation., PMID:40259710
Unsupervised machine learning identifies distinct systemic lupus erythematosus patient endotypes with differential response to belimumab., PMID:40244828
CD70 recruitment to the immunological synapse is dependent on CD20 in B cells., PMID:40232798
Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection., PMID:40222009
Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic., PMID:40173043
Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection., PMID:40173042
Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia., PMID:40149717
Aberrant Lower CD6 Expression on Peripheral B Cells Associated With Liver/Kidney Injury and Autoantibody Production of Systemic Lupus Erythematosus Patients., PMID:40134233
Comprehensive Phenotyping and Cytokine Production of Circulating B Cells Associate Resting Memory B Cells With Early Antibody-mediated Rejection in Kidney Transplant Recipients., PMID:40124243
Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease., PMID:40078987
IL-4 alters TLR7-induced B cell developmental program in lupus., PMID:40068727
CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity., PMID:40046047
Development and Preclinical Evaluation of [64Cu]Cu-NOTA-ABDB6: A CD70 and Albumin Dual-Binding Tracer with Improved Pharmacokinetics., PMID:40015924
Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975
Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:39939347
Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase., PMID:39931747
BNT162b2 mRNA vaccination affects the gut microbiome composition of patients with follicular lymphoma and chronic lymphocytic leukemia., PMID:39930533
Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept., PMID:39925810
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
Myricetin exposure reduces PC differentiation in vitro in primary human B cells., PMID:39875809
Maternal obesity associates with altered humoral immunity in blood and colostrum., PMID:39870213
Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis., PMID:39867643
The Role of Dendritic Cells in Adaptive Immune Response Induced by OVA/PDDA Nanoparticles., PMID:39852855
Bivalent OX40 Aptamer and CpG as Dual Agonists for Cancer Immunotherapy., PMID:39841045
Novel Sarcoidosis Epitope Augments MHCII, CD80/CD86 Expression, Promotes B-Cell Differentiation and IgG Production., PMID:39836049
Genetically reprogrammed exosomes for immunotherapy of acute myeloid leukemia., PMID:39815621
Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells., PMID:39812873
Longitudinal monitoring of class-switched memory-B cell proportions identifies plausible germinal center failure in patients with suspected immune disorders., PMID:39791256
Subset of DN Memory B Cells Expressing Low Levels of Inhibitory Receptor BTLA Is Enriched in SLE Patients., PMID:39768154
Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus., PMID:39740932
PIgR Autoantibody-abundant Circulating Vesicles Contributes to Biliary Injury in Biliary Atresia., PMID:39733605
Donor HLA-DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21 low CD27 - B cells with high-avidity germline B-cell receptors., PMID:39713394
B Cell Receptor Repertoire Analysis of the CD21lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis., PMID:39707660
Herpesvirus Antibodies Are Correlated With Greater Expression of p16 in the T Cells of Humans., PMID:39703789
Characterization of anti-asialo-GM1 monoclonal antibody., PMID:39693935
Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development., PMID:39687626
For research use only. Not for human or drug use.
