Catalog No.
RVV13903
Expression system
Mammalian Cells
Species reactivity
Vaccinia
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Applications
ELISA, Neutralization
Target
Protein L1, Virion membrane protein M25, VACWR088, L1R
Concentration
2.17 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P07612
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
7D11
Note
For research use only.
Development of a replication-defective mpox virus platform for fundamental and therapeutic research. [RVV13903]
Protective immunity to vaccinia virus induced by vaccination with multiple recombinant outer membrane proteins of intracellular and extracellular virions., PMID:15367588
Human T-cell responses to vaccinia virus envelope proteins., PMID:17005679
Resistance of a vaccinia virus A34R deletion mutant to spontaneous rupture of the outer membrane of progeny virions on the surface of infected cells., PMID:17553539
Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein., PMID:17688903
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine., PMID:18234801
Targeting the vaccinia virus L1 protein to the cell surface enhances production of neutralizing antibodies., PMID:18485547
Disparity between levels of in vitro neutralization of vaccinia virus by antibody to the A27 protein and protection of mice against intranasal challenge., PMID:18524827
Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans., PMID:19162289
Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization., PMID:19257896
L1R, A27L, A33R and B5R vaccinia virus genes expressed by fowlpox recombinants as putative novel orthopoxvirus vaccines., PMID:23578094
Enhanced Expression of the L1R Gene of Vaccinia Virus by the tPA Signal Sequence Inserted in a Fowlpox-Based Recombinant Vaccine., PMID:39460282