Catalog No.
FHD19430
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Conjugation
Unconjugated
Target
IL7R, Interleukin-7 receptor subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, CD127, CDw127, IL-7R subunit alpha, IL-7RA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P16871
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
4A10
Frequency and stability of populations of CD4+ and CD4+CD25+Foxp3+CD127lo Treg in healthy adults defined by cytometry using monoclonal antibodies to T cell associated molecules., PMID:40464367
Postnatal epigenetic differences in calves following transient fetal infection with bovine viral diarrhea virus., PMID:40316897
Functional insights of an uncommon hypomorphic variant in IL2RG as a monogenic cause of CVID-like disease with antibody deficiency and T CD4 lymphopenia., PMID:40170851
Humanized Mouse Model of Graft-Versus-Host Disease Utilizing Nonirradiated NOD-scid-IL-2Rγnull Mice., PMID:40100599
T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells., PMID:40092978
Pre-B-cell leukemia transcription factor 1 contributes to liver fibrosis by enabling IL-7 signaling in HSC., PMID:40080840
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors., PMID:40074330
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
Flexible deformation and special interface structure in nanoparticle-stabilized Pickering bubbles strengthen the immunological response as adjuvant., PMID:39851034
Direct Inhibitory Effect of HTLV-1-Infected T Cells on the Production of Anti-Ro/SS-A Antibody by B Cells from Patients with Sjögren's Syndrome., PMID:39775490
Combining anti-checkpoint immunotherapies and cancer vaccines as a novel strategy in oncological therapy: A review., PMID:39662393
IQGAP1 promotes early B cell development, is essential for the development of marginal zone (MZ) B cells, and is critical for both T-dependent and T-independent antibody responses., PMID:39585462
Rescue immune tolerance induction with a recombinant factor Fc-fused VIII: prospective ReITIrate study of clinical, humoral and cellular immune responses., PMID:39583653
Neutralizing the IL-7Rα limits injury in experimental ANCA-associated glomerulonephritis., PMID:39572086
Pro-inflammatory NK-like T cells are expanded in the blood and inflamed intestine in Crohn's disease., PMID:39521274
Molecular Hydrogen Therapy in Sjögren's Syndrome With Pulmonary Arterial Hypertension and Right-sided Heart Failure: A Case Report of Improved Immune Markers Including Treg, B Cells and Plasma Cell., PMID:39477378
Markers of T-cell dysfunction and not inflammaging predict the waning of humoral responses to SARS-CoV-2 mRNA booster vaccination in people with HIV., PMID:39474654
Flow Cytometric Immunophenotyping: Minimal Differences in Fresh and Cryopreserved Peripheral Blood Mononuclear Cells versus Whole Blood., PMID:39457632
Visnagin alleviates rheumatoid arthritis via its potential inhibitory impact on malate dehydrogenase enzyme: in silico, in vitro, and in vivo studies., PMID:39390383
Surface Immune Checkpoints as Potential Biomarkers in Physiological Pregnancy and Recurrent Pregnancy Loss., PMID:39273326
Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at risk for type 1 diabetes., PMID:39137044
A human autoimmune organoid model reveals IL-7 function in coeliac disease., PMID:39048815
rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors., PMID:39043602
Changing Characteristics of Treg/Th17 Cells in the Nasal Mucosa of a Mouse Model of Allergic Rhinitis and the Effect of Intervention with Anti-IL-17 Antibody., PMID:38926112
A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice., PMID:38670234
Regulation of the Function of T Follicular Helper Cells and B Cells in Type 1 Diabetes Mellitus by the OX40/OX40L Axis., PMID:38625053
Choosing T-cell sources determines CAR-T cell activity in neuroblastoma., PMID:38601159
The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis., PMID:38518105
OMIP-101: 27-color flow cytometry panel for immunophenotyping of major leukocyte populations in fixed whole blood., PMID:38343094
[Establishment of a 21-color Panel for the Detection of Immune Cell Subsets
in Human Non-small Cell Lung Cancer Tumor Tissues with Flow Cytometry]., PMID:38296626
Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer., PMID:38290769
[Efficacy and safety of fourth-generation CD19 CAR-T expressing IL7 and CCL19 along with PD-1 monoclonal antibody for relapsed or refractory large B-cell lymphoma]., PMID:38049333
Single-cell mass cytometric analysis of peripheral immunity and multiplex plasma marker profiling of non-small cell lung cancer patients receiving PD-1 targeting immune checkpoint inhibitors in comparison with platinum-based chemotherapy., PMID:37901220
A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy., PMID:37874823
[Study the involvement of Langerin in mediating epicutaneous sensitization of atopic dermatitis-like mouse model]., PMID:37813655
Flow cytometric analysis of innate lymphoid cells: challenges and solutions., PMID:37809100
Natalizumab Treatment of Relapsing Remitting Multiple Sclerosis Has No Long-Term Effects on the Proportion of Circulating Regulatory T Cells., PMID:37715885
Vitamin D3 mitigates autoimmune inflammation caused by activation of myeloid dendritic cells in SLE., PMID:37702410
Effect of thymectomy on the frequencies of peripheral regulatory B and T lymphocytes in patients with Myasthenia gravis-a pilot study., PMID:37668142
Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases., PMID:37586773
Toll-like receptors and IL-7 as potential biomarkers for immune-mediated necrotizing myopathies., PMID:37562045
Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis., PMID:37506196
Association of NK Cells with the Severity of Fibrosis in Patients with Chronic Hepatitis C., PMID:37443584
Clinical and immune-related factors associated with exacerbation in adults with well-controlled generalized myasthenia gravis., PMID:37266422
Expression Improvement of Recombinant Plasmids of the Interleukin-7 Gene in Chitosan-Derived Nanoparticles and Their Elevation of Mice Immunity., PMID:37237481
Is peripheral blood immunophenotyping useful to understand the etiology of Idiopathic Granulomatous?, PMID:37202243
Circulating Regulatory T Cell Subsets in Patients with Sarcoidosis., PMID:37189479
CD4+CD25+CD127loFOXP3+ cell in food allergy: Does it predict anaphylaxis?, PMID:37169554
Dynamics of CD4+ T-Cells and Neutralizing Antibody Responses to Three Consecutive Doses of Inactivated COVID-19 Vaccines in PLWH., PMID:37168513
Role of MXRA8 in Ross River Virus Disease Pathogenesis., PMID:37036079
For research use only. Not for human or drug use.
