InVivoMAb Anti-MACV GP1 glycoprotein Antibody (MAC1)

Catalog No.

VVV25401

Species reactivity

Machupo virus (MACV)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Applications

ELISA, Neutralization

Target

Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC, AVI34_00004

Concentration

4.39 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q6PXP4

Form

Liquid

Storage buffer

100 mM Pro-Ac, 20 mM Arg, pH 5.0.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

MAC1

Note

For research use only. Not suitable for clinical or therapeutic use.

Differences in Glycoprotein Complex Receptor Binding Site Accessibility Prompt Poor Cross-Reactivity of Neutralizing Antibodies between Closely Related Arenaviruses., PMID:28100617

Bivalent Junin & Machupo experimental vaccine based on alphavirus RNA replicon vector., PMID:32111526

Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain., PMID:34132574

Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies., PMID:35315691

Glycoprotein-Specific Polyclonal Antibodies Targeting Machupo Virus Protect Guinea Pigs against Lethal Infection., PMID:38932403

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InVivoMAb Anti-MACV GP1 glycoprotein Antibody (MAC1).pdf