Catalog No.
PHD68601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human UCP1 (Met1-Thr307).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Solute carrier family 25 member 7,UCP1,SLC25A7,Mitochondrial brown fat uncoupling protein 1,Thermogenin,UCP,UCP 1
Purification
Purified by antigen affinity column.
Accession
P25874
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The interaction between rumen microbiota and neurotransmitters plays an important role in the adaptation of phenological changes in Tibetan sheep., PMID:40414864
No UCP1 in the kidney., PMID:40120980
Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr-/-.Leiden mice., PMID:39463193
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice., PMID:38909257
Two-stage evolution of mammalian adipose tissue thermogenesis., PMID:38843333
[Cold stimulation promotes interleukin-4 secretion by mucosal-associated invariant T cells in the adipose tissue to promote adipose browning in mice]., PMID:38081605
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice., PMID:37130842
Selective deficiency of UCP-1 and adropin may lead to different subtypes of anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:36670189
Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway., PMID:36581870
Lcn2 mediates adipocyte-muscle-tumor communication and hypothermia in pancreatic cancer cachexia., PMID:36243318
Identification of a prognostic signature in colorectal cancer using combinatorial algorithm-driven analysis., PMID:35043584
UCP1 expression in the mouse adrenal gland is not upregulated by thermogenic conditions., PMID:34129966
Myosin 1c: A novel regulator of glucose uptake in brown adipocytes., PMID:33965643
Insulin Modulates the Bioenergetic and Thermogenic Capacity of Rat Brown Adipocytes In Vivo by Modulating Mitochondrial Mosaicism., PMID:33287103
Localization of uncoupling protein 1 (UCP-1) in the sebaceous gland of the dorsal region in the Sunda porcupine (Hystrix javanica)., PMID:33055467
The kallikrein-kinin pathway as a mechanism for auto-control of brown adipose tissue activity., PMID:32358539
The gut hormone secretin triggers a gut-brown fat-brain axis in the control of food intake., PMID:32271980
A novel follicle-stimulating hormone vaccine for controlling fat accumulation., PMID:32171969
A subpopulation of Bdnf-e1-expressing glutamatergic neurons in the lateral hypothalamus critical for thermogenesis control., PMID:31918913
A simplified enriched environment increases body temperature and suppresses cancer progression in mice., PMID:31852850
Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling., PMID:31758074
Coping with exposure to hypoxia: modifications in stress parameters in gilthead seabream (Sparus aurata) fed spirulina (Arthrospira platensis) and brewer's yeast (Saccharomyces cerevisiae)., PMID:31273480
Important Trends in UCP3 Investigation., PMID:31133866
Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours., PMID:31114671
Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men., PMID:30873124
The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis., PMID:30737786
Expression, purification and biological characterisation of recombinant human irisin (12.5 kDa)., PMID:30733760
Differentiation of bone marrow-derived cells toward thermogenic adipocytes in white adipose tissue induced by the β3 adrenergic stimulation., PMID:30624970
Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency., PMID:30502051
Transdifferentiation of Muscle Satellite Cells to Adipose Cells Using CRISPR/Cas9-Mediated Targeting of MyoD., PMID:30367407
Central IGF1 improves glucose tolerance and insulin sensitivity in mice., PMID:29259155
Honokiol exerts dual effects on browning and apoptosis of adipocytes., PMID:29136581
FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes., PMID:29107292
A low-protein, high-carbohydrate diet increases browning in perirenal adipose tissue but not in inguinal adipose tissue., PMID:28870477
Blocking FSH induces thermogenic adipose tissue and reduces body fat., PMID:28538730
The Role of Thyrotropin Receptor Activation in Adipogenesis and Modulation of Fat Phenotype., PMID:28469599
Pig has no uncoupling protein 1., PMID:28442343
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis., PMID:28414329
Flow Cytometric Isolation and Differentiation of Adipogenic Progenitor Cells into Brown and Brite/Beige Adipocytes., PMID:28244038
Progenitors in Peripheral Nerves Launch Heterotopic Ossification., PMID:28198109
UCP1, the mitochondrial uncoupling protein of brown adipocyte: A personal contribution and a historical perspective., PMID:27916641
Hedgehog signaling in bone regulates whole-body energy metabolism through a bone-adipose endocrine relay mediated by PTHrP and adiponectin., PMID:27740628
Irisin inhibition of growth hormone secretion in cultured tilapia pituitary cells., PMID:27693813
Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots., PMID:27653320
Castration induced browning in subcutaneous white adipose tissue in male mice., PMID:27608598
Thermogenic activation represses autophagy in brown adipose tissue., PMID:27339605
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion., PMID:26880110
Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice., PMID:26808348
Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes., PMID:26556104
The expression of UCP3 directly correlates to UCP1 abundance in brown adipose tissue., PMID:26518386
For research use only. Not for human or drug use.
