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Anti-HIV-1 Matrix protein p17/MA protein Antibody (M33)

Catalog #:   RVV19304 Specific References (122) DATASHEET
Host species: Human
Isotype: IgG1
Applications: ELISA, FCM, WB
Expression system: Mammalian Cells
Overview

Catalog No.

RVV19304

Expression system

Mammalian Cells

Species reactivity

Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1)

Host species

Human

Isotype

IgG1

Clonality

Monoclonal

Target

Gag-Pol polyprotein, Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide 1, SP1, p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, 3.4.23.16, PR, Retropepsin, Reverse transcriptase/ribonuclease H, 2.7.7.49, 2.7.7.7, 3.1.26.13, Exoribonuclease H, 3.1.13.2, p66 RT, p51 RT, p15, Integrase, IN, 2.7.7.-, 3.1.-.-, gag-pol

Concentration

2.81 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03367

Applications

ELISA, FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

M33

Data Image
  • SDS-PAGE
    SDS PAGE for HIV-1 Matrix protein p17/MA protein Antibody (M33)
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

HIV-1 Matrix Protein p17 and its Receptors. PMID: 26302809

The HIV-1 Matrix Protein p17 Does Cross the Blood-Brain Barrier. PMID: 34668776

HIV-1 matrix protein p17: a candidate antigen for therapeutic vaccines against AIDS. PMID: 20816696

High expression of HIV-1 matrix protein p17 in both lymphoma and lymph node tissues of AIDS patients. PMID: 35939971

Functions of the HIV-1 matrix protein p17. PMID: 16608119

Maturation of the matrix and viral membrane of HIV-1. PMID: 34353956

HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide. PMID: 35763571

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2. PMID: 22904195

Role of Autophagy in HIV-1 Matrix Protein p17-Driven Lymphangiogenesis. PMID: 28592537

The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2. PMID: 24736615

Total chemical synthesis of N-myristoylated HIV-1 matrix protein p17: structural and mechanistic implications of p17 myristoylation. PMID: 15280532

HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders. PMID: 28871125

HIV-1 matrix protein p17 promotes lymphangiogenesis and activates the endothelin-1/endothelin B receptor axis. PMID: 24482377

HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness. PMID: 29021819

Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis. PMID: 26578780

Cellular aspartyl proteases promote the unconventional secretion of biologically active HIV-1 matrix protein p17. PMID: 27905556

The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes. PMID: 22558273

The HIV-1 matrix protein p17 activates the transcription factors c-Myc and CREB in human B cells. PMID: 20402410

Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion. PMID: 8659115

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma. PMID: 26469385

Angiogenic, lymphangiogenic and adipogenic effects of HIV-1 matrix protein p17. PMID: 26333571

Role of Autophagy in Von Willebrand Factor Secretion by Endothelial Cells and in the In Vivo Thrombin-Antithrombin Complex Formation Promoted by the HIV-1 Matrix Protein p17. PMID: 32188077

Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications. PMID: 31673058

In-depth analysis of compartmentalization of HIV-1 matrix protein p17 in PBMC and plasma. PMID: 28072889

Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice. PMID: 27799525

A CXCR1 haplotype hampers HIV-1 matrix protein p17 biological activity. PMID: 25121556

Binding to PI(4,5)P2 is indispensable for secretion of B-cell clonogenic HIV-1 matrix protein p17 variants. PMID: 34273353

HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activation. PMID: 22262769

Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants. PMID: 30248376

Flexible and rigid structures in HIV-1 p17 matrix protein monitored by relaxation and amide proton exchange with NMR. PMID: 24373876

Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17. PMID: 9094619

HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype. PMID: 18310327

Structural similarity between the p17 matrix protein of HIV-1 and interferon-gamma. PMID: 8065455

HIV-1 matrix protein p17 binds to monocytes and selectively stimulates MCP-1 secretion: role of transcriptional factor AP-1. PMID: 18042260

HIV-1 matrix protein p17 increases the production of proinflammatory cytokines and counteracts IL-4 activity by binding to a cellular receptor. PMID: 12105273

Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015. PMID: 18570590

HIV-1 matrix protein p17 prevents loss of CD28 expression during IL-2-induced maturation of naïve CD8(+) T cells. PMID: 21482826

HIV-1 p17 matrix protein interacts with heparan sulfate side chain of CD44v3, syndecan-2, and syndecan-4 proteoglycans expressed on human activated CD4+ T cells affecting tumor necrosis factor alpha and interleukin 2 production. PMID: 1457192

HIV-1 matrix protein p17 resides in cell nuclei in association with genomic RNA. PMID: 24456624

Synthetic HIV-1 matrix protein p17-based AT20-KLH therapeutic immunization in HIV-1-infected patients receiving antiretroviral treatment: A phase I safety and immunogenicity study. PMID: 23166320

Molecular interaction studies of HIV-1 matrix protein p17 and heparin: identification of the heparin-binding motif of p17 as a target for the development of multitarget antagonists. PMID: 16713032

The HIV-1 matrix protein p17 can be efficiently delivered by intranasal route in mice using the TLR 2/6 agonist MALP-2 as mucosal adjuvant. PMID: 15134345

The central domain of the matrix protein of HIV-1: influence on protein structure and virus infectivity. PMID: 12542496

HIV-1 matrix protein p17 enhances the proliferative activity of natural killer cells and increases their ability to secrete proinflammatory cytokines. PMID: 32588322

Effects of HIV on the Tumor Microenvironment. PMID: 29664204

Characterization and epitope mapping of a panel of monoclonal antibodies against HIV-1 matrix protein. PMID: 27907055

Effect of Glu12-His89 Interaction on Dynamic Structures in HIV-1 p17 Matrix Protein Elucidated by NMR. PMID: 29571970

Unconventional secretion of viral proteins. PMID: 24732873

Detection of HIV-1 matrix protein p17 quasispecies variants in plasma of chronic HIV-1-infected patients by ultra-deep pyrosequencing. PMID: 26912608

Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation. PMID: 16817760

HIV-1 matrix protein p17 modulates in vivo preactivated murine T-cell response and enhances the induction of systemic and mucosal immunity against intranasally co-administered antigens. PMID: 33467638

Oncogenic Effects of HIV-1 Proteins, Mechanisms Behind. PMID: 26057863

Long-lasting humoral immune response induced in HIV-1-infected patients by a synthetic peptide (AT20) derived from the HIV-1 matrix protein p17 functional epitope. PMID: 8654825

Refined solution structure of p17, the HIV matrix protein. PMID: 28747658

A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17. PMID: 26621736

Correction to Supporting Information for Dolcetti et al., Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis. PMID: 17210199

HIV-1 matrix protein: a mysterious regulator of the viral life cycle. PMID: 22705971

The HIV-1 matrix protein does not interact directly with the protein interactive domain of AP-3δ. PMID: 30100245

Cartilage oligomeric matrix protein is differentially expressed in human subcutaneous adipose tissue and regulates adipogenesis. PMID: 17411366

Regulating the functions of the HIV-1 matrix protein. PMID: 25950938

Lignin as immobilization matrix for HIV p17 peptide used in immunosensing. PMID: 37222611

Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity. PMID: 12465460

HIV-1 replication. PMID: 25704763

A natural HIV p17 protein variant up-regulates the LMP-1 EBV oncoprotein and promotes the growth of EBV-infected B-lymphocytes: implications for EBV-driven lymphomagenesis in the HIV setting. PMID: 18553937

Solution X-ray scattering reveals a novel structure of calmodulin complexed with a binding domain peptide from the HIV-1 matrix protein p17. PMID: 8619916

Conservative hydrophobic interdomain contacts of IFN-gamma remain in P17 matrix protein of HIV-1. PMID: 27030269

Trimer Enhancement Mutation Effects on HIV-1 Matrix Protein Binding Activities. PMID: 18602957

Synthetic peptide AT20 coupled to KLH elicits antibodies against a conserved conformational epitope from a major functional area of the HIV-1 matrix protein p17. PMID: 8503172

Assembly of the matrix protein of simian immunodeficiency virus into virus-like particles. PMID: 9085253

Inhibition of early and late events of the HIV-1 replication cycle by cytoplasmic Fab intrabodies against the matrix protein, p17. PMID: 31375578

Heterogeneous Nuclear Ribonucleoprotein A1 and Lamin A/C Modulate Nucleocytoplasmic Shuttling of Avian Reovirus p17. PMID: 25900164

Cross-Reactivity Between Influenza Matrix- and HIV-1 P17-Specific CTL-A Large Cohort Study. PMID: 18225865

The N-terminal basic domain of the HIV-1 matrix protein does not contain a conventional nuclear localization sequence but is required for DNA binding and protein self-association. PMID: 1629961

The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions. PMID: 9123837

Pleiotropic mutations in the HIV-1 matrix protein that affect diverse steps in replication. PMID: 9514761

Membrane-induced alterations in HIV-1 Gag and matrix protein-protein interactions. PMID: 18947403

HIV-1 p17 matrix protein enhances type I interferon responses through the p17-OLA1-STING axis., PMID:38132845

Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity., PMID:37222611

Quantitative Human Immunodeficiency Virus (HIV)-1 Antibodies Correlate With Plasma HIV-1 RNA and Cell-associated DNA Levels in Children on Antiretroviral Therapy., PMID:30668843

Characterization and epitope mapping of a panel of monoclonal antibodies against HIV-1 matrix protein., PMID:29664204

Common antibody dependent cell mediated cytotoxicity (ADCC) antibody epitopes of HIV-1 CRF01_AE Env and Gag in early HIV-1 infected individuals., PMID:29602284

Expression, Purification and Characterization of Hiv-1 Capsid Precursor Protein p41., PMID:29508209

Long-lasting humoral immune response induced in HIV-1-infected patients by a synthetic peptide (AT20) derived from the HIV-1 matrix protein p17 functional epitope., PMID:26057863

Cross-Reactivity Between Influenza Matrix- and HIV-1 P17-Specific CTL-A Large Cohort Study., PMID:25900164

Enhanced production of functional extracellular single chain variable fragment against HIV-1 matrix protein from Escherichia coli by sequential simplex optimization., PMID:24884357

The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2., PMID:24736615

Synthetic HIV-1 matrix protein p17-based AT20-KLH therapeutic immunization in HIV-1-infected patients receiving antiretroviral treatment: A phase I safety and immunogenicity study., PMID:24456624

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2., PMID:22904195

Toward preserving the structure of the antigenic peptide p17-1 from the HIV-1 p17 protein in nanostructured films., PMID:22103071

Fine epitope specificity of anti-erythropoietin antibodies reveals molecular mimicry with HIV-1 p17 protein: a pathogenetic mechanism for HIV-1-related anemia., PMID:21849287

Baculovirus display of single chain antibody (scFv) using a novel signal peptide., PMID:21092083

HIV-1 matrix protein p17: a candidate antigen for therapeutic vaccines against AIDS., PMID:20816696

The HIV-1 matrix protein p17 activates the transcription factors c-Myc and CREB in human B cells., PMID:20402410

Production and purification of immunologically active core protein p24 from HIV-1 fused to ricin toxin B subunit in E. coli., PMID:19196485

Synthetic peptide AT20 coupled to KLH elicits antibodies against a conserved conformational epitope from a major functional area of the HIV-1 matrix protein p17., PMID:18602957

Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED., PMID:18302803

Replication-deficient mutant Herpes Simplex Virus-1 targets professional antigen presenting cells and induces efficient CD4+ T helper responses., PMID:17553721

The HIV-1 matrix protein p17 can be efficiently delivered by intranasal route in mice using the TLR 2/6 agonist MALP-2 as mucosal adjuvant., PMID:16713032

Antibody recognition of synthetic peptides mimicking immunodominant regions of HIV-1 p24 and p17 proteins., PMID:15786866

Contribution of virus-like particles to the immunogenicity of human immunodeficiency virus type 1 Gag-derived vaccines in mice., PMID:15650195

Part of the C-terminal tail of the envelope gp41 transmembrane glycoprotein of human immunodeficiency virus type 1 is exposed on the surface of infected cells and is involved in virus-mediated cell fusion., PMID:15604440

Preclinical studies on immunogenicity of the HIV-1 p17-based synthetic peptide AT20-KLH., PMID:15386266

Construction and characterization of a fluorescently labeled infectious human immunodeficiency virus type 1 derivative., PMID:15367647

Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions., PMID:14645565

HIV-1 matrix protein p17 enhances the proliferative activity of natural killer cells and increases their ability to secrete proinflammatory cytokines., PMID:12542496

HIV-1 matrix protein p17 increases the production of proinflammatory cytokines and counteracts IL-4 activity by binding to a cellular receptor., PMID:12105273

Genetic characterization of HIV type 1 gag p17 matrix genes in isolates from infected mothers lacking perinatal transmission., PMID:11779356

Gag-derived proteins of HIV-1 isolates from Indian patients: cloning, expression, and purification of p17 of B- and C-subtypes., PMID:11281711

Slight difference in primary amino acid sequence of p17 matrix protein of HIV-1 exerts profound influence on its antigenicity., PMID:9645195

Immunologic cross-reaction between HIV type 1 p17 and Mycoplasma hyorhinis variable lipoprotein., PMID:9546801

Inhibition of early and late events of the HIV-1 replication cycle by cytoplasmic Fab intrabodies against the matrix protein, p17., PMID:9085253

Characterization of human immunodeficiency virus type 1 p17 matrix protein motifs associated with mother-to-child transmission., PMID:8676472

Mutations in the N-terminal region of human immunodeficiency virus type 1 matrix protein block intracellular transport of the Gag precursor., PMID:8411340

Prevalence and persistence of antibody titers to recombinant HIV-1 core and matrix proteins in HIV-1 infection., PMID:8315575

Characterization of murine monoclonal antibodies directed against the submembrane protein p17 of HIV-1., PMID:7503941

[HIV-1 p17 matrix protein is transported into the cell nucleus and binds with genomic viral RNA]., PMID:8483474

HIV-1 matrix protein p17 resides in cell nuclei in association with genomic RNA., PMID:1457192

Identification of a gag protein epitope conserved among all four groups of primate immunodeficiency viruses by using monoclonal antibodies., PMID:1383399

Decline in CTL and antibody responses to HIV-1 p17 and p24 antigens in HIV-1-infected hemophiliacs irrespective of disease progression. A 5-year follow-up study., PMID:1281655

Characterization of monoclonal antibodies against the human immunodeficiency virus matrix protein, p17gag: identification of epitopes exposed at the surfaces of infected cells., PMID:1714518

HIV-1 gag proteins in virions and in infected cell fractions., PMID:1751761

Kinetics of infected cell appearance as a determinant of number of human immunodeficiency virus-1 infectious units., PMID:2497763

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-HIV-1 Matrix protein p17/MA protein Antibody (M33) [RVV19304]
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