Catalog No.
PHD48001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BGN (Val49-Leu182).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SLRR1A,PG-S1,BGN,Biglycan,Bone/cartilage proteoglycan I
Purification
Purified by antigen affinity column.
Accession
P21810
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Rapid and specific screening of monoclonal antibodies in hybridoma supernatants by an enzyme-based dipstick immunoassay., PMID:39579494
Molecular basis for antibody recognition of multiple drug-peptide/MHC complexes., PMID:38781214
Hybrid Immunity from Gam-COVID-Vac Vaccination and Natural SARS-CoV-2 Infection Confers Broader Neutralizing Activity against Omicron Lineage VOCs Than Revaccination or Reinfection., PMID:38250868
Genomic architecture of carcass and pork traits and their association with immune capacity., PMID:38113634
Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis., PMID:37958972
Deep learning neural network image analysis of immunohistochemical protein expression reveals a significantly reduced expression of biglycan in breast cancer., PMID:36972253
Breast cancer dataset with biomarker Biglycan., PMID:36879615
Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy., PMID:36531688
A novel circular RNA confers trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer through regulating ferroptosis., PMID:35234341
Identification of Hub Biomarkers and Immune-Related Pathways Participating in the Progression of Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis., PMID:35069594
Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)., PMID:34506743
Assessment of cancer prevention effect of exercise., PMID:34459390
Immune-Intrinsic Myd88 Directs the Production of Antibodies With Specificity for Extracellular Matrix Components in Primary Sjögren's Syndrome., PMID:34381449
Selective and noncovalent targeting of RAS mutants for inhibition and degradation., PMID:33976200
Context-dependent monoclonal antibodies against protein carbamidomethyl-cysteine., PMID:33232360
OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton., PMID:32950603
Identification of proteomic signatures associated with COPD frequent exacerbators., PMID:31121174
Significance of biglycan and osteopontin as non-invasive markers of liver fibrosis in patients with chronic hepatitis B virus and chronic hepatitis C virus., PMID:30385593
Non-Glycanated Biglycan and LTBP4: Leveraging the extracellular matrix for Duchenne Muscular Dystrophy therapeutics., PMID:29481844
Elevated circulating TGF-β is not the cause of increased atherosclerosis development in biglycan deficient mice., PMID:29182988
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease., PMID:28538136
Interleukin-1α induces focal degradation of biglycan and tissue degeneration in an in-vitro ovine meniscal model., PMID:27615609
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1., PMID:27253668
IgE Reactivity, Work Related Allergic Symptoms, Asthma Severity, and Quality of Life in Bakers with Occupational Asthma., PMID:27161107
UV irradiation-induced production of monoglycosylated biglycan through downregulation of xylosyltransferase 1 in cultured human dermal fibroblasts., PMID:25936869
Evaluation of global differential gene and protein expression in primary Pterygium: S100A8 and S100A9 as possible drivers of a signaling network., PMID:24825356
Biglycan modulates angiogenesis and bone formation during fracture healing., PMID:24373744
Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development., PMID:24272803
Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units., PMID:23851162
CD99 is a novel prognostic stromal marker in non-small cell lung cancer., PMID:22392539
Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype., PMID:21454527
Expression of extracellular matrix proteins in adenomatoid odontogenic tumor., PMID:20070486
Hypoxia-inducible factor-1 {alpha} expression predicts superior survival in patients with diffuse large B-cell lymphoma treated with R-CHOP., PMID:20048181
IL-2 and proteoglycans synergistically induce antigen-specific B-cell responses--a possible immune response in the hyperplastic myasthenia thymus., PMID:18937982
Extracellular matrix markers for disease progression and follow-up of therapies in familial amyloid polyneuropathy V30M TTR-related., PMID:18776590
The potential functional interaction of biglycan and WISP-1 in controlling differentiation and proliferation of osteogenic cells., PMID:18701807
Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues., PMID:18620607
Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance., PMID:18371351
The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo., PMID:17681134
Immunohistochemical identification of decorin and biglycan in human dentin: a correlative field emission scanning electron microscopy/transmission electron microscopy study., PMID:17516017
Overexpression of biglycan in the heart of transgenic mice: an antibody microarray study., PMID:17269742
Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation., PMID:16283572
Colocalization of the collagen-binding proteoglycans decorin, biglycan, fibromodulin and lumican with different cells in human gingiva., PMID:15613083
Proteoglycans and catabolic products of proteoglycans present in ligament., PMID:15329049
Simple repeat replacements support similar functions of distinct repeats in inter-species mRNA homologs., PMID:15019980
Glomerular expression of biglycan and decorin and urinary levels of decorin in primary glomerular disease., PMID:14964452
Changes in HNK-1 epitope and collagen type IX in the aqueous humour of patients with pseudoexfoliation syndrome., PMID:14704908
[Immunohistochemical localization and expression of fibromodulin in the periodontium]., PMID:14642103
Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis., PMID:12835223
Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels., PMID:12798075