Catalog No.
RHG17601
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
Q08722
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1315
CDH17-targeting CAR-NK cells synergize with CD47 blockade for potent suppression of gastrointestinal cancers., PMID:40487639
Oncolytic viruses targeting CD47: a new road to success?, PMID:40341033
Nanobody-Based PET Imaging of CD47 Expression in Thyroid Carcinoma., PMID:40326602
N-deglycosylation targeting chimera (DGlyTAC): a strategy for immune checkpoint proteins inactivation by specifically removing N-glycan., PMID:40289109
Nanobody Engineered and Photosensitiser Loaded Bacterial Outer Membrane Vesicles Potentiate Antitumour Immunity and Immunotherapy., PMID:40240911
An oncolytic vaccinia virus expressing anti-CD47 nanobody exerts enhanced antitumor activity by mediating innate and adaptive immune cell infiltration and activation in the lymphoma tumor microenvironment., PMID:40207734
Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon., PMID:40121481
Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer., PMID:39843440
Oncolytic vaccinia virus armed with anti-CD47 nanobody elicit potent antitumor effects on multiple tumor models via enhancing innate and adoptive immunity., PMID:39794937
Framework Nucleic Acid-Nanobody Fusion Probe-Based Pharmacokinetics Modulation and Analysis for Efficient Positron Emission Tomography Imaging., PMID:39714093
Engineered probiotic-mediated intratumoral delivery and controlled release of bacterial collagenase for cancer therapy., PMID:39582690
Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation., PMID:39488258
Engineered Outer Membrane Vesicles as Nanosized Immune Cell Engagers for Enhanced Solid Tumor Immunotherapy., PMID:39454084
Reprogramming tumor microenvironment with precise photothermal therapy by calreticulin nanobody-engineered probiotics., PMID:39303415
Engineered Cellular Vesicles Displaying Glycosylated Nanobodies for Cancer Immunotherapy., PMID:38977426
Nanobody-Engineered Biohybrid Bacteria Targeting Gastrointestinal Cancers Induce Robust STING-Mediated Anti-Tumor Immunity., PMID:38888519
BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma., PMID:38783333
Delivery of CD47-SIRPα checkpoint blocker by BCMA-directed UCAR-T cells enhances antitumor efficacy in multiple myeloma., PMID:38266806
A Novel Anti-CD47 Nanobody Tetramer for Cancer Therapy., PMID:38247566
Bispecific Nanobody-Aptamer Conjugates for Enhanced Cancer Therapy in Solid Tumors., PMID:38225704
Two birds with one stone: human SIRPα nanobodies for functional modulation and in vivo imaging of myeloid cells., PMID:38164132
AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors., PMID:38113032
An off-the-shelf small extracellular vesicle nanomedicine for tumor targeting therapy., PMID:37967724
Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field., PMID:36959204
Development and Characterization of Nanobody-Derived CD47 Theranostic Pairs in Solid Tumors., PMID:36939440
Engineered Bacterial Outer Membrane Vesicles as Controllable Two-Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy., PMID:35985666
In Situ Tumor Vaccine Expressing Anti-CD47 Antibody Enhances Antitumor Immunity., PMID:35837100
Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha., PMID:34917090
Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments., PMID:32019780
Preclinical development of a novel CD47 nanobody with less toxicity and enhanced anti-cancer therapeutic potential., PMID:31931812
Homology Modeling-Based in Silico Affinity Maturation Improves the Affinity of a Nanobody., PMID:31461846
Programmable bacteria induce durable tumor regression and systemic antitumor immunity., PMID:31270504
Localized CD47 blockade enhances immunotherapy for murine melanoma., PMID:28874561
For research use only. Not for human or drug use.
