Catalog No.
RHD90201
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
AT1BR, AGTR1B, Angiotensin II type-1 receptor, AGTR1, AT1AR, Type-1 angiotensin II receptor, AT2R1B, AT2R1, AT1, AGTR1A
Concentration
0.18 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P30556
Applications
FCM, IP, RIA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1316
Lower Expression of SARS-CoV-2 Host Cell Entry Genes in the Intestinal Mucosa of IBD Patients With Quiescent or Mildly Active Disease., PMID:40279370
Dysregulated autoantibodies targeting AGTR1 are associated with the accumulation of COVID-19 symptoms., PMID:39805853
Cell type-specific expression of angiotensin receptors in the human lung with implications for health, aging, and chronic disease., PMID:38948835
Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity., PMID:35264564
Antibodies against Angiotensin II Type 1 and Endothelin 1 Type A Receptors in Cardiovascular Pathologies., PMID:35055116
Functionally Active Antibodies to the Angiotensin II Type 1-Receptor Measured by a Luminometric Bioassay Do Not Correlate With Clinical Manifestations in Systemic Sclerosis: A Comparison With Antibodies to Vascular Receptors and Topoisomerase I Detected by ELISA., PMID:34956217
Angiotensin II receptor I auto-antibodies following SARS-CoV-2 infection., PMID:34788328
Anti-AT1R autoantibodies and prediction of the severity of Covid-19., PMID:34772541
Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway., PMID:34757123
Defective Uteroplacental Vascular Remodeling in Preeclampsia: Key Molecular Factors Leading to Long Term Cardiovascular Disease., PMID:34681861
Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers., PMID:34380734
Association of Angiotensin Receptor Autoantibodies With Cardiovascular Abnormalities in Preeclampsia., PMID:34096322
Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension., PMID:33980031
β1-adrenergic and Muscarinic Acetylcholine Type 2 Receptor Antibodies are Increased in Graves' Hyperthyroidism and Decrease During Antithyroid Therapy., PMID:33434937
ARHGDIB and AT1R autoantibodies are differentially related to the development and presence of chronic antibody-mediated rejection and fibrosis in kidney allografts., PMID:33358038
Prevalence of AT1R antibody (AT1R-Ab) among Malaysian multi-ethnic population., PMID:32736900
Angiotensin II receptor 1 antibodies associate with post-transplant focal segmental glomerulosclerosis and proteinuria., PMID:32615995
Angiotensin II Type-1 Receptor Antibodies Are Associated With Active Allograft Dysfunction Following Pediatric Liver Transplantation., PMID:32101982
A bivalent antihypertensive vaccine targeting L-type calcium channels and angiotensin AT1 receptors., PMID:31625597
Expression of Components of the Renin-Angiotensin System by the Embryonic Stem Cell-Like Population within Keloid Lesions., PMID:31348346
Functional autoantibodies against Endothelin-1 receptor type A and Angiotensin II receptor type 1 in patients with preeclampsia., PMID:30527110
Effect of Angiotensin II Receptor Type 1 Antibodies on Kidney Allograft Function., PMID:29507275
Revealing a new mode of sensitization induced by mechanical circulatory support devices: Impact of anti-AT1 R antibodies., PMID:29245181
Autoantibodies against AT1 and α1-adrenergic receptors predict arterial stiffness progression in normotensive subjects over a 5-year period., PMID:29097625
Immune Response of A Novel ATR-AP205-001 Conjugate Anti-hypertensive Vaccine., PMID:28974760
Angiotensin II Type 1 receptor antibodies are associated with inflammatory cytokines and poor clinical outcomes in pediatric kidney transplantation., PMID:28927645
Refractory Vascular Rejection in a Hand Allograft in the Presence of Antibodies Against Angiotensin II (Type 1) Receptor., PMID:28767535
Non-HLA Antibodies Impact on C4d Staining, Stellate Cell Activation and Fibrosis in Liver Allografts., PMID:28665894
A 3-Center Study Reveals New Insights Into the Impact of Non-HLA Antibodies on Lung Transplantation Outcome., PMID:27973391
Immediate and Catastrophic Antibody-Mediated Rejection in a Lung Transplant Recipient With Anti-Angiotensin II Receptor Type 1 and Anti-Endothelin-1 Receptor Type A Antibodies., PMID:27640901
Non-HLA Antibodies May Accelerate Immune Responses After Intestinal and Multivisceral Transplantation., PMID:27495766
Anti-Angiotensin II Type 1 Receptor and Anti-Endothelial Cell Antibodies: A Cross-Sectional Analysis of Pathological Findings in Allograft Biopsies., PMID:27222934
The impact of angiotensin II type 1 receptor antibodies on post-heart transplantation outcome in Heart Mate II bridged recipients., PMID:26675563
Genetic variants in the renin-angiotensin system predict response to bevacizumab in cancer patients., PMID:26509357
Complement Split Products C3a/C5a and Receptors: Are They Regulated by Circulating Angiotensin II Type 1 Receptor Autoantibody in Severe Preeclampsia?, PMID:26485247
Antibodies against AT1-receptor in transplantation (diagnostics, treatment, clinical relevance)., PMID:25936314
Angiotensin II type 1 receptor antibody precipitating acute vascular rejection in kidney transplantation., PMID:25807851
Angiotensin II increases matrix metalloproteinase 2 expression in human aortic smooth muscle cells via AT1R and ERK1/2., PMID:25767191
Final results of a phase II study of paclitaxel, bevacizumab, and gemcitabine as first-line therapy for patients with HER2-negative metastatic breast cancer., PMID:25119930
Serum levels for midkine, a heparin-binding growth factor, inversely correlate with angiotensin and endothelin receptor autoantibody titers in patients with macroangiopathy., PMID:25056169
Agonistic autoantibodies against the angiotensin AT1 receptor increase in unstable angina patients after stent implantation., PMID:25025993
In arterial occlusive disease autoantibodies against ETAR and AT(1)R correlate with each other but are not associated with classical cardiovascular risk factors., PMID:24627317
Autoantibodies and biomarkers of endothelial cell activation in atherosclerosis., PMID:24627313
Angiotensin II receptor type 1 autoantibodies promote endothelial microparticles formation through activating p38 MAPK pathway., PMID:24609215
Influence of autoantibodies against AT1 receptor and AGTR1 polymorphisms on candesartan-based antihypertensive regimen: results from the study of optimal treatment in hypertensive patients with anti-AT1-receptor autoantibodies trial., PMID:24131669
Autoantibodies isolated from preeclamptic patients induce endothelial dysfunction via interaction with the angiotensin II AT1 receptor., PMID:24122090
Interplay between immune responses to HLA and non-HLA self-antigens in allograft rejection., PMID:23876679
Bevacizumab plus preoperative chemotherapy in operable HER2 negative breast cancer: biomarkers and pathologic response., PMID:23397155
Detection of antibodies in eluates of immunoadsorption causing humoural rejection in patients after solid organ transplantation., PMID:23357164
[Expression and significance of AT1-AA and ET1 in materal peripheral blood, umbilical cord blood and placenta in preeclampsia]., PMID:23302726
For research use only. Not for human or drug use.
