Catalog No.
PHD24301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human AKR1C4 (Met1-Tyr323).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
3-alpha-HSD1,3alpha-hydroxysteroid 3-dehydrogenase,DD4,Aldo-keto reductase family 1 member C4,AKR1C4,DD-4,CDR,HAKRA,Chlordecone reductase,3-alpha-hydroxysteroid dehydrogenase type I,CHDR,Dihydrodiol dehydrogenase 4
Purification
Purified by antigen affinity column.
Accession
P17516
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Characterization of a highly specific monoclonal antibody against human aldo-keto reductase AKR1C3., PMID:30639543
Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system., PMID:18574251
Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate., PMID:15582534
Hepatocyte nuclear factor (HNF)-4 alpha/gamma, HNF-1 alpha, and vHNF-1 regulate the cell-specific expression of the human dihydrodiol dehydrogenase (DD)4/AKR1C4 gene., PMID:12220531
Co-operative regulation of the transcription of human dihydrodiol dehydrogenase (DD)4/aldo-keto reductase (AKR)1C4 gene by hepatocyte nuclear factor (HNF)-4alpha/gamma and HNF-1alpha., PMID:11284743
Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members., PMID:10510318