Catalog No.
PHD23701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SMPD1 (Gly319-Gly579).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
aSMase,SMPD1,Acid sphingomyelinase,Sphingomyelin phosphodiesterase,ASM
Purification
Purified by antigen affinity column.
Accession
P17405
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging., PMID:39866701
Pharmacologically induced endolysosomal cholesterol imbalance through clinically licensed drugs itraconazole and fluoxetine impairs Ebola virus infection in vitro., PMID:34919035
Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia., PMID:33057972
Nitric oxide induces HepG2 cell death via extracellular signal-regulated protein kinase activation by regulating acid sphingomyelinase., PMID:33025504
Increased expression of long noncoding RNAs LOC100652951 and LOC100506036 in T cells from patients with rheumatoid arthritis facilitates the inflammatory responses., PMID:26616293
Regulation of hematogenous tumor metastasis by acid sphingomyelinase., PMID:25851537
Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis., PMID:22771321
Is active acid sphingomyelinase required for the antiproliferative response to rituximab?, PMID:21454466
Killer cell immunoglobulin-like receptor 3DL1 licenses CD16-mediated effector functions of natural killer cells., PMID:20664023
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology., PMID:20111001
For research use only. Not for human or drug use.
