Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering: results from phase 1 and phase 1b/2a clinical studies., PMID:40383129
An ANGPTL4 inhibitory antibody safely improves lipid profiles in non-human primates., PMID:40360349
Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia., PMID:40344904
Genetics of remnant cholesterol., PMID:40277396
Histologic Characterization of Tumor-Adjacent Mammary Adipose Tissue in Normal-Weight and Overweight/Obese Patients with Triple-Negative Breast Cancer., PMID:39456610
Bone-protective effects of neutralizing angiopoietin-like protein 4 monoclonal antibody in rheumatoid arthritis., PMID:39367607
Attenuating Epithelial-to-Mesenchymal Transition in Cancer through Angiopoietin-Like 4 Inhibition in a 3D Tumor Microenvironment Model., PMID:37987244
Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation., PMID:37649607
Dual role of ANGPTL4 in inflammation., PMID:37300585
High glucose-induced IL-7/IL-7R upregulation of dermal fibroblasts inhibits angiogenesis in a paracrine way in delayed diabetic wound healing., PMID:37217704
The potential crosstalk between tumor and plasma cells and its association with clinical outcome and immunotherapy response in bladder cancer., PMID:37138324
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures., PMID:36787365
Danlou Tablet May Alleviate Vascular Injury Caused by Chronic Intermittent Hypoxia through Regulating FIH-1, HIF-1, and Angptl4., PMID:36285165
A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia., PMID:36016656
Mitochondrial bioenergetics in ocular fibroblasts of two myasthenia gravis cases., PMID:35746973
Mechanistic and therapeutic links between rheumatoid arthritis and diabetes mellitus., PMID:35306615
Angiopoietin-like proteins 3, 4 and 8 are linked to cardiovascular function in naïve sub-clinical and overt hypothyroid patients receiving levothyroxine therapy., PMID:34739390
Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice., PMID:34255741
Angiopoietin-like proteins in atherosclerosis., PMID:34153276
PM2.5 exposure exaggerates the risk of adverse birth outcomes in pregnant women with pre-existing hyperlipidemia: Modulation role of adipokines and lipidome., PMID:33992945
Mobilization efficiency is critically regulated by fat via marrow PPARδ., PMID:33538151
New Trends in Dyslipidemia Treatment., PMID:33177309
ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a., PMID:32638512
Danlou Tablet Improves Chronic Intermittent Hypoxia-Induced Dyslipidemia and Arteriosclerosis by HIF-1α-Angptl4 mRNA Signaling Pathway., PMID:32623702
Research Progress on the Involvement of ANGPTL4 and Loss-of-Function Variants in Lipid Metabolism and Coronary Heart Disease: Is the "Prime Time" of ANGPTL4-Targeted Therapy for Coronary Heart Disease Approaching?, PMID:32500296
Retraction Note to: The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4., PMID:32103388
The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases., PMID:32059999
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism., PMID:32034094
Hyposialylated angiopoietin-like-4 induces apoptosis of podocytes via β1 Integrin/FAK signaling in diabetic nephropathy., PMID:31981598
Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia., PMID:31931117
Angiopoietin-like proteins as therapeutic targets for cardiovascular disease: focus on lipid disorders., PMID:31856617
Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes., PMID:31602400
Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia., PMID:31164474
New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk., PMID:30893111
Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway., PMID:30840953
Angiopoietin-like proteins in multiple sclerosis., PMID:30784773
Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4., PMID:30518876
ANGPTL3 Inhibitors - Their Role in Cardiovascular Disease Through Regulation of Lipid Metabolism., PMID:30504621
Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia., PMID:29752428
Longitudinal autoantibody responses against tumor-associated antigens decrease in breast cancer patients according to treatment modality., PMID:29386014
Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart., PMID:29353241
Development of bead based multiplexed immunoassay for evaluation of midkine, syndecan-1, and ANGPTL4 in patient serum., PMID:29309212
Chiglitazar Preferentially Regulates Gene Expression via Configuration-Restricted Binding and Phosphorylation Inhibition of PPARγ., PMID:29056962
Angiopoietin-like 3 in lipoprotein metabolism., PMID:28984319
Expression of angiogenic mediators in a patient with a retinal artery occlusion., PMID:28774531
A decade of progress on the genetic basis of coronary artery disease. Practical insights for the internist., PMID:28395986
ANGIOPOIETIN-LIKE 4 CORRELATES WITH RESPONSE TO INTRAVITREAL RANIBIZUMAB INJECTIONS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION., PMID:28151839
Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition., PMID:28143927
High Concentrations of Angiopoietin-Like Protein 4 Detected in Serum from Patients with Rheumatoid Arthritis Can Be Explained by Non-Specific Antibody Reactivity., PMID:28107351
Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis., PMID:27376874