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InVivoMAb Anti-Human/Mouse ANGPTL4 Antibody (Iv0129)

Catalog #:   VHJ51401 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: Neutralization
Accession: Q9BY76
Overview

Catalog No.

VHJ51401

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

PGAR, Angiopoietin-related protein 4, Hepatic fibrinogen/angiopoietin-related protein, ANGPTL4, Angiopoietin-like protein 4, HFARP, ARP4

Concentration

1.15 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9BY76

Applications

Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0129

Data Image
References

Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering: results from phase 1 and phase 1b/2a clinical studies., PMID:40383129

An ANGPTL4 inhibitory antibody safely improves lipid profiles in non-human primates., PMID:40360349

Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia., PMID:40344904

Genetics of remnant cholesterol., PMID:40277396

Histologic Characterization of Tumor-Adjacent Mammary Adipose Tissue in Normal-Weight and Overweight/Obese Patients with Triple-Negative Breast Cancer., PMID:39456610

Bone-protective effects of neutralizing angiopoietin-like protein 4 monoclonal antibody in rheumatoid arthritis., PMID:39367607

Attenuating Epithelial-to-Mesenchymal Transition in Cancer through Angiopoietin-Like 4 Inhibition in a 3D Tumor Microenvironment Model., PMID:37987244

Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation., PMID:37649607

Dual role of ANGPTL4 in inflammation., PMID:37300585

High glucose-induced IL-7/IL-7R upregulation of dermal fibroblasts inhibits angiogenesis in a paracrine way in delayed diabetic wound healing., PMID:37217704

The potential crosstalk between tumor and plasma cells and its association with clinical outcome and immunotherapy response in bladder cancer., PMID:37138324

Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures., PMID:36787365

Danlou Tablet May Alleviate Vascular Injury Caused by Chronic Intermittent Hypoxia through Regulating FIH-1, HIF-1, and Angptl4., PMID:36285165

A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia., PMID:36016656

Mitochondrial bioenergetics in ocular fibroblasts of two myasthenia gravis cases., PMID:35746973

Mechanistic and therapeutic links between rheumatoid arthritis and diabetes mellitus., PMID:35306615

Angiopoietin-like proteins 3, 4 and 8 are linked to cardiovascular function in naïve sub-clinical and overt hypothyroid patients receiving levothyroxine therapy., PMID:34739390

Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice., PMID:34255741

Angiopoietin-like proteins in atherosclerosis., PMID:34153276

PM2.5 exposure exaggerates the risk of adverse birth outcomes in pregnant women with pre-existing hyperlipidemia: Modulation role of adipokines and lipidome., PMID:33992945

Mobilization efficiency is critically regulated by fat via marrow PPARδ., PMID:33538151

New Trends in Dyslipidemia Treatment., PMID:33177309

ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a., PMID:32638512

Danlou Tablet Improves Chronic Intermittent Hypoxia-Induced Dyslipidemia and Arteriosclerosis by HIF-1α-Angptl4 mRNA Signaling Pathway., PMID:32623702

Research Progress on the Involvement of ANGPTL4 and Loss-of-Function Variants in Lipid Metabolism and Coronary Heart Disease: Is the "Prime Time" of ANGPTL4-Targeted Therapy for Coronary Heart Disease Approaching?, PMID:32500296

Retraction Note to: The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4., PMID:32103388

The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases., PMID:32059999

Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism., PMID:32034094

Hyposialylated angiopoietin-like-4 induces apoptosis of podocytes via β1 Integrin/FAK signaling in diabetic nephropathy., PMID:31981598

Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia., PMID:31931117

Angiopoietin-like proteins as therapeutic targets for cardiovascular disease: focus on lipid disorders., PMID:31856617

Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes., PMID:31602400

Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia., PMID:31164474

New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk., PMID:30893111

Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway., PMID:30840953

Angiopoietin-like proteins in multiple sclerosis., PMID:30784773

Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4., PMID:30518876

ANGPTL3 Inhibitors - Their Role in Cardiovascular Disease Through Regulation of Lipid Metabolism., PMID:30504621

Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia., PMID:29752428

Longitudinal autoantibody responses against tumor-associated antigens decrease in breast cancer patients according to treatment modality., PMID:29386014

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart., PMID:29353241

Development of bead based multiplexed immunoassay for evaluation of midkine, syndecan-1, and ANGPTL4 in patient serum., PMID:29309212

Chiglitazar Preferentially Regulates Gene Expression via Configuration-Restricted Binding and Phosphorylation Inhibition of PPARγ., PMID:29056962

Angiopoietin-like 3 in lipoprotein metabolism., PMID:28984319

Expression of angiogenic mediators in a patient with a retinal artery occlusion., PMID:28774531

A decade of progress on the genetic basis of coronary artery disease. Practical insights for the internist., PMID:28395986

ANGIOPOIETIN-LIKE 4 CORRELATES WITH RESPONSE TO INTRAVITREAL RANIBIZUMAB INJECTIONS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION., PMID:28151839

Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition., PMID:28143927

High Concentrations of Angiopoietin-Like Protein 4 Detected in Serum from Patients with Rheumatoid Arthritis Can Be Explained by Non-Specific Antibody Reactivity., PMID:28107351

Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis., PMID:27376874

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Human/Mouse ANGPTL4 Antibody (Iv0129) [VHJ51401]
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