Machine learning and molecular modeling reveal potential inhibitors of the human metapneumovirus fusion protein., PMID:40498230
A Computationally Designed Prefusion Stabilized Human Metapneumovirus Fusion Protein Vaccine Antigen Elicited a Potent Neutralization Response., PMID:40432132
Clinical Insights and Advancements in Human Metapneumovirus Management and Prognosis., PMID:40351504
Cangrelor and AVN-944 as repurposable candidate drugs for hMPV: analysis entailed by AI-driven in silico approach., PMID:40316857
An overview of progress in human metapneumovirus (hMPV) research: Structure, function, and therapeutic opportunities., PMID:40286981
A tumor-binding antibody with cross-reactivity to viral antigens., PMID:40009215
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro., PMID:39776441
Plant Cell Culture-Derived Saponin Adjuvant Enhances Immune Response Against a Stabilized Human Metapneumovirus Pre-Fusion Vaccine Candidate., PMID:39772095
Emerging lineages A2.2.1 and A2.2.2 of human metapneumovirus (hMPV) in pediatric respiratory infections: Insights from India., PMID:39717865
Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus., PMID:39550381
Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer., PMID:39054318
Mucosal bivalent live attenuated vaccine protects against human metapneumovirus and respiratory syncytial virus in mice., PMID:38898106
Novel insights into the host cell glycan binding profile of human metapneumovirus., PMID:38690874
VLPs generated by the fusion of RSV-F or hMPV-F glycoprotein to HIV-Gag show improved immunogenicity and neutralizing response in mice., PMID:38641492
A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers., PMID:38496645
A general computational design strategy for stabilizing viral class I fusion proteins., PMID:38351001
A chimeric influenza virus vaccine expressing fusion protein epitopes induces protection from human metapneumovirus challenge in mice., PMID:38155756
A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein., PMID:38117059
Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface., PMID:38032197
Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes., PMID:37974334
Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus., PMID:37738240
Structural basis for respiratory syncytial virus and human metapneumovirus neutralization., PMID:37544710
Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode., PMID:37516111
Neutralising antibodies against human metapneumovirus., PMID:37499668
Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases., PMID:37337079
The emergence, impact, and evolution of human metapneumovirus variants from 2014 to 2021 in Spain., PMID:37178807
The HRA2pl fusion peptide exerts in vitro antiviral activity against human respiratory paramyxoviruses and pneumoviruses., PMID:37153148
A general computational design strategy for stabilizing viral class I fusion proteins., PMID:36993551
Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus., PMID:36130517
A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein., PMID:36003370
Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein., PMID:35944529
Elicitation of pneumovirus-specific B cell responses by a prefusion-stabilized respiratory syncytial virus F subunit vaccine., PMID:35731888
Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus., PMID:35696580
Profiling of hMPV F-specific antibodies isolated from human memory B cells., PMID:35538099
Zoonotic Origins of Human Metapneumovirus: A Journey from Birds to Humans., PMID:35458407
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins., PMID:35288548
Detailed Analyses of Molecular Interactions between Favipiravir and RNA Viruses In Silico., PMID:35215932
Avian Cell Line DuckCelt®-T17 Is an Efficient Production System for Live-Attenuated Human Metapneumovirus Vaccine Candidate Metavac®., PMID:34696298
Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8+ T cells., PMID:34675220
Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses., PMID:34551978
The Prevalence and Genetic Characterization of Human Metapneumovirus in Bulgaria, 2016-2019., PMID:34304230
Structure, Immunogenicity, and Conformation-Dependent Receptor Binding of the Postfusion Human Metapneumovirus F Protein., PMID:34160259
Sendai Virus-Vectored Vaccines That Express Envelope Glycoproteins of Respiratory Viruses., PMID:34072332
Antibody recognition of the Pneumovirus fusion protein trimer interface., PMID:33035266
Insights into immune evasion of human metapneumovirus: novel 180- and 111-nucleotide duplications within viral G gene throughout 2014-2017 seasons in Barcelona, Spain., PMID:32957052
SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses., PMID:32056846
Evaluation of pre- and post-fusion Human metapneumovirus F proteins as subunit vaccine candidates in mice., PMID:32007293
Whole genome sequencing and phylogenetic analysis of human metapneumovirus strains from Kenya and Zambia., PMID:31898474
Antibody Epitopes of Pneumovirus Fusion Proteins., PMID:31849961
Characterization of potent RSV neutralizing antibodies isolated from human memory B cells and identification of diverse RSV/hMPV cross-neutralizing epitopes., PMID:31402751
For research use only. Not for human or drug use.
