Terminal Effector CD8 T Cells Defined by an IKZF2(+)IL-7R(-) Transcriptional Signature Express FcgammaRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity. PMID: 31519862
Peripheral blood CD4(+)CD25(+)CD127(low) regulatory T cells are significantly increased by tocilizumab treatment in patients with rheumatoid arthritis: increase in regulatory T cells correlates with clinical response. PMID: 25604867
Nivolumab and ipilimumab are associated with distinct immune landscape changes and response-associated immunophenotypes. PMID: 32369447
Interleukin 7 receptor alpha as a potential therapeutic target in transplantation. PMID: 19585222
The suppressive effect on CD4 T cell alloresponse against endothelial HLA-DR via PD-L1 induced by anti-A/B ligation. PMID: 32578199
Elucidation of the Effects of a Current X-SCID Therapy on Intestinal Lymphoid Organogenesis Using an In Vivo Animal Model. PMID: 32017983
Combination of CD4(+)CD25(+)CD127(-) regulatory T cells with MLC-BE and BE-Ab2: an efficient evaluation of the therapy of paternal lymphocyte induced immunization in unexplained recurrent spontaneous abortion patients. PMID: 26097590
CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes. PMID: 33301420
Increasing the biological activity of IL-2 and IL-15 through complexing with anti-IL-2 mAbs and IL-15Rα-Fc chimera. PMID: 24512738
IL-23 and PSMA-targeted duo-CAR T cells in Prostate Cancer Eradication in a preclinical model. PMID: 31937346
Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. PMID: 16785889
[Epidermotropic T cell lymphomas as models for tumor progression]. PMID: 16457762
IL-7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum-infected mice. PMID: 29566311
Combination immunotherapy with clinical-scale enriched human gammadelta T cells, hu14.18 antibody, and the immunocytokine Fc-IL7 in disseminated neuroblastoma. PMID: 16322312
Anti-IL-7 receptor-alpha reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function. PMID: 22733769
IL-7 Mediated Homeostatic Expansion of Human CD4+CD25+FOXP3+ Regulatory T Cells After Depletion With Anti-CD25 Monoclonal Antibody. PMID: 27306531
Multiple sclerosis treatment effects on plasma cytokine receptor levels. PMID: 28941836
IL-2/IL-2 antibody immune complex regulates HSV-induced inflammation through induction of IL-2 receptor alpha, beta, and gamma in a mouse model. PMID: 26213097
Decidual CD4+CD25+CD127dim/- regulatory T cells in patients with unexplained recurrent spontaneous miscarriage. PMID: 21130556
Tolerance-induced receptor selection: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection. PMID: 14962198
TGF-beta(1) and contact mediated suppression by CD4(+)CD25(+)CD127(-) T regulatory cells of patients with self-limiting hepatitis E. PMID: 27720959
Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation. PMID: 23301543
B cell development and its deregulation to transformed states at the pre-B cell receptor-expressing pre-BII cell stage. PMID: 16323425
[Chromatin dynamics in gene rearrangement]. PMID: 16613168
Diphtheria toxin-based receptor-specific chimaeric toxins as targeted therapies. PMID: 8822152
Peripheral imbalanced TFH/TFR ratio correlates with intrathecal IgG synthesis in multiple sclerosis at clinical onset. PMID: 29882478
Engagement of IL-1 receptor accessory protein (IL-1RAcP) with the monoclonal antibody AY19 provides co-activating signals and prolongs the CD2-induced proliferation of peripheral blood lymphocytes. PMID: 21600927
Cooperation between IL-7 and the pre-B cell receptor: a key to B cell selection. PMID: 12457615
Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera. PMID: 18589435
In-vitro inhibition of IFNgamma+ iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function. PMID: 22905732
Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells. PMID: 23280063
Therapy with anti-TNFalpha antibody enhances number and function of Foxp3(+) regulatory T cells in inflammatory bowel diseases. PMID: 20848510
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage. PMID: 31628339
Oncogenic basic amino acid insertions at the extracellular juxtamembrane region of IL7RA cause receptor hypersensitivity. PMID: 30670441
Alemtuzumab mediates the CD39+ T-regulatory cell response via CD23+ macrophages. PMID: 33306219
Decline of programmed death-1-positive circulating T regulatory cells predicts more favourable clinical outcome of patients with melanoma under immune checkpoint blockade. PMID: 31361026
The role of the preBCR, the interleukin-7 receptor, and homotypic interactions during B-cell development. PMID: 10933590
[Role of circulating T follicular helper subsets and T follicular helper effector memory cells in systemic lupus erythematosus]. PMID: 30669756
Autosomal primary immunodeficiencies affecting human bone marrow B-cell differentiation. PMID: 11213811
Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition. PMID: 31061414
IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates. PMID: 30367166
Accumulation of memory precursor CD8 T cells in regressing tumors following combination therapy with vaccine and anti-PD-1 antibody. PMID: 24728077
Pre-B and pre-T-cell receptors: conservation of strategies in regulating early lymphocyte development. PMID: 10933593
IgH DJ rearrangements within T-ALL correlate with cCD79a expression, an immature/TCRgammadelta phenotype and absence of IL7Ralpha/CD127 expression. PMID: 15483677
Elevated IFN-alpha/beta levels in a streptozotocin-induced type I diabetic mouse model promote oxidative stress and mediate depletion of spleen-homing CD8+ T cells by apoptosis through impaired CCL21/CCR7 axis and IL-7/CD127 signaling. PMID: 26192098
Dysregulation of Circulating Tfr/Tfh Ratio in Primary biliary cholangitis. PMID: 28941291
Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation. PMID: 31406267
Expression of the IL-7 receptor alpha-chain is down regulated on the surface of CD4 T-cells by the HIV-1 Tat protein. PMID: 25333710
Lack of antigen-specific immune responses in anti-IL-7 receptor alpha chain antibody-treated Peyer's patch-null mice following intestinal immunization with microencapsulated antigen. PMID: 12209648
IL-7 Induces an Epitope Masking of gammac Protein in IL-7 Receptor Signaling Complex. PMID: 28127156
Co-transplantation of human fetal thymus, bone and CD34(+) cells into young adult immunodeficient NOD/SCID IL2Rgamma(null) mice optimizes humanized mice that mount adaptive antibody responses. PMID: 25725428
Frequency and stability of populations of CD4+ and CD4+CD25+Foxp3+CD127lo Treg in healthy adults defined by cytometry using monoclonal antibodies to T cell associated molecules., PMID:40464367
Postnatal epigenetic differences in calves following transient fetal infection with bovine viral diarrhea virus., PMID:40316897
Functional insights of an uncommon hypomorphic variant in IL2RG as a monogenic cause of CVID-like disease with antibody deficiency and T CD4 lymphopenia., PMID:40170851
Humanized Mouse Model of Graft-Versus-Host Disease Utilizing Nonirradiated NOD-scid-IL-2Rγnull Mice., PMID:40100599
T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells., PMID:40092978
Pre-B-cell leukemia transcription factor 1 contributes to liver fibrosis by enabling IL-7 signaling in HSC., PMID:40080840
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors., PMID:40074330
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
Flexible deformation and special interface structure in nanoparticle-stabilized Pickering bubbles strengthen the immunological response as adjuvant., PMID:39851034
Direct Inhibitory Effect of HTLV-1-Infected T Cells on the Production of Anti-Ro/SS-A Antibody by B Cells from Patients with Sjögren's Syndrome., PMID:39775490
Combining anti-checkpoint immunotherapies and cancer vaccines as a novel strategy in oncological therapy: A review., PMID:39662393
IQGAP1 promotes early B cell development, is essential for the development of marginal zone (MZ) B cells, and is critical for both T-dependent and T-independent antibody responses., PMID:39585462
Rescue immune tolerance induction with a recombinant factor Fc-fused VIII: prospective ReITIrate study of clinical, humoral and cellular immune responses., PMID:39583653
Neutralizing the IL-7Rα limits injury in experimental ANCA-associated glomerulonephritis., PMID:39572086
Pro-inflammatory NK-like T cells are expanded in the blood and inflamed intestine in Crohn's disease., PMID:39521274
Molecular Hydrogen Therapy in Sjögren's Syndrome With Pulmonary Arterial Hypertension and Right-sided Heart Failure: A Case Report of Improved Immune Markers Including Treg, B Cells and Plasma Cell., PMID:39477378
Markers of T-cell dysfunction and not inflammaging predict the waning of humoral responses to SARS-CoV-2 mRNA booster vaccination in people with HIV., PMID:39474654
Flow Cytometric Immunophenotyping: Minimal Differences in Fresh and Cryopreserved Peripheral Blood Mononuclear Cells versus Whole Blood., PMID:39457632
Visnagin alleviates rheumatoid arthritis via its potential inhibitory impact on malate dehydrogenase enzyme: in silico, in vitro, and in vivo studies., PMID:39390383
Surface Immune Checkpoints as Potential Biomarkers in Physiological Pregnancy and Recurrent Pregnancy Loss., PMID:39273326
Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at risk for type 1 diabetes., PMID:39137044
A human autoimmune organoid model reveals IL-7 function in coeliac disease., PMID:39048815
rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors., PMID:39043602
Changing Characteristics of Treg/Th17 Cells in the Nasal Mucosa of a Mouse Model of Allergic Rhinitis and the Effect of Intervention with Anti-IL-17 Antibody., PMID:38926112
A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice., PMID:38670234
Regulation of the Function of T Follicular Helper Cells and B Cells in Type 1 Diabetes Mellitus by the OX40/OX40L Axis., PMID:38625053
Choosing T-cell sources determines CAR-T cell activity in neuroblastoma., PMID:38601159
The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis., PMID:38518105
OMIP-101: 27-color flow cytometry panel for immunophenotyping of major leukocyte populations in fixed whole blood., PMID:38343094
[Establishment of a 21-color Panel for the Detection of Immune Cell Subsets
in Human Non-small Cell Lung Cancer Tumor Tissues with Flow Cytometry]., PMID:38296626
Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer., PMID:38290769
[Efficacy and safety of fourth-generation CD19 CAR-T expressing IL7 and CCL19 along with PD-1 monoclonal antibody for relapsed or refractory large B-cell lymphoma]., PMID:38049333
Single-cell mass cytometric analysis of peripheral immunity and multiplex plasma marker profiling of non-small cell lung cancer patients receiving PD-1 targeting immune checkpoint inhibitors in comparison with platinum-based chemotherapy., PMID:37901220
A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy., PMID:37874823
[Study the involvement of Langerin in mediating epicutaneous sensitization of atopic dermatitis-like mouse model]., PMID:37813655
Flow cytometric analysis of innate lymphoid cells: challenges and solutions., PMID:37809100
Natalizumab Treatment of Relapsing Remitting Multiple Sclerosis Has No Long-Term Effects on the Proportion of Circulating Regulatory T Cells., PMID:37715885
Vitamin D3 mitigates autoimmune inflammation caused by activation of myeloid dendritic cells in SLE., PMID:37702410
Effect of thymectomy on the frequencies of peripheral regulatory B and T lymphocytes in patients with Myasthenia gravis-a pilot study., PMID:37668142
Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases., PMID:37586773
Toll-like receptors and IL-7 as potential biomarkers for immune-mediated necrotizing myopathies., PMID:37562045
Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis., PMID:37506196
Association of NK Cells with the Severity of Fibrosis in Patients with Chronic Hepatitis C., PMID:37443584
Clinical and immune-related factors associated with exacerbation in adults with well-controlled generalized myasthenia gravis., PMID:37266422
Expression Improvement of Recombinant Plasmids of the Interleukin-7 Gene in Chitosan-Derived Nanoparticles and Their Elevation of Mice Immunity., PMID:37237481
Is peripheral blood immunophenotyping useful to understand the etiology of Idiopathic Granulomatous?, PMID:37202243
Circulating Regulatory T Cell Subsets in Patients with Sarcoidosis., PMID:37189479
CD4+CD25+CD127loFOXP3+ cell in food allergy: Does it predict anaphylaxis?, PMID:37169554
Dynamics of CD4+ T-Cells and Neutralizing Antibody Responses to Three Consecutive Doses of Inactivated COVID-19 Vaccines in PLWH., PMID:37168513
Role of MXRA8 in Ross River Virus Disease Pathogenesis., PMID:37036079
For research use only. Not for human or drug use.
